4,4′-Bis(2-Bromoacetyl)biphenyl CAS 4072-67-7 I-Daclatasvir Dihydrochloride Ubumsulwa obuphakathi >98.0% (HPLC)
I-Shanghai Ruifu Chemical Co., Ltd. ingumkhiqizi ohamba phambili we-4,4'-Bis(2-Bromoacetyl)biphenyl (CAS: 4072-67-7) enekhwalithi ephezulu.I-Ruifu Chemical inganikeza ukulethwa komhlaba wonke, intengo encintisanayo, isevisi enhle kakhulu, amanani amancane kanye nenqwaba etholakalayo.Thenga i-4,4'-Bis(2-Bromoacetyl)biphenyl,Please contact: alvin@ruifuchem.com
| Igama Lekhemikhali | 4,4'-Bis(2-Bromoacetyl)biphenyl |
| Omqondofana | 4,4'-Bis(Bromoacetyl)biphenyl;1,1'-[1,1'-Biphenyl]-4,4'-diylbis[2-Bromoethan-1-one];I-Daclatasvir Ukungcola 7 |
| Isimo Sesitoko | Ku-Stock, Commercial Production |
| Inombolo ye-CAS | 4072-67-7 |
| I-Molecular Formula | I-C16H12Br2O2 |
| Isisindo samangqamuzana | 396.07 g/mol |
| I-Melting Point | 226.0~227.0℃ |
| Ukuminyana | 1.622±0.06 g/cm3 |
| I-COA ne-MSDS | Iyatholakala |
| Umsuka | Shanghai, China |
| Isigaba | Okumaphakathi kwe-Daclatasvir Dihydrochloride (CAS: 1009119-65-6) |
| Ibhrendi | I-Ruifu Chemical |
| Izinto | Imininingwane | Imiphumela |
| Ukubukeka | Okuqinile | Okuqinile |
| Ukuhlanzeka / Indlela Yokuhlaziya | >98.0% (HPLC) | 98.5% |
| I-Infrared Spectrum | Ihambisana Nesakhiwo | Iyahambisana |
| 1H NMR Spectrum | Ihambisana Nesakhiwo | Iyahambisana |
| Isiphetho | Umkhiqizo uhloliwe futhi uthobela imininingwane enikeziwe | |
| Isicelo | Okumaphakathi kwe-Daclatasvir Dihydrochloride (CAS: 1009119-65-6) | |
Iphakheji:Ibhodlela eliFluorinated, isikhwama se-Aluminium foil, 25kg/Cardboard Drum, noma ngokwezidingo zekhasimende.
Isimo Sesitoreji:Gcina isitsha sivalwe ngokuqinile futhi usigcine endaweni epholile, eyomile futhi enomoya omuhle kude nezinto ezingahambelani.Vikela ekukhanyeni nakumswakama.
Ukuthumela:Zilethe emhlabeni wonke ngendiza, yi-FedEx/DHL Express.Nikeza ukulethwa okusheshayo nokuthembekile.
Indlela Yokuthenga?Sicela uxhumaneDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
Iminyaka engu-15 Yokuhlangenwe nakho?Sinesipiliyoni seminyaka engaphezu kwe-15 ekwakhiweni nasekuthumeleni kwamanye amazwe uhla olubanzi lwezinga eliphezulu lokuxhumanisa imithi noma amakhemikhali amahle.
Izimakethe Eziyinhloko?Thengisa emakethe yasekhaya, eNyakatho Melika, eYurophu, eNdiya, eKorea, eJapane, e-Australia, njll.
Izinzuzo?Ikhwalithi ephezulu, intengo ethengekayo, izinsizakalo ezichwepheshile nokusekelwa kobuchwepheshe, ukulethwa okusheshayo.
IkhwalithiIsiqiniseko?Isistimu yokulawula ikhwalithi eqinile.Imishini yobuchwepheshe yokuhlaziya ifaka i-NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, NOMA, KF, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, njll.
Amasampula?Imikhiqizo eminingi inikeza amasampula wamahhala wokuhlolwa kwekhwalithi, izindleko zokuthumela kufanele zikhokhelwe amakhasimende.
Ukuhlolwa Kwemboni?Wamukelekile ekucwaningweni kwemboni.Sicela wenze i-aphoyintimenti kusengaphambili.
I-MOQ?Ayikho i-MOQ.I-oda elincane liyamukeleka.
Isikhathi sokuthumela? Uma kungaphakathi kwesitoko, ukulethwa kwezinsuku ezintathu kuqinisekisiwe.
Ezokuthutha?By Express (FedEx, DHL), by Air, by Sea.
Amadokhumenti?Ngemuva kwenkonzo yokuthengisa: I-COA, i-MOA, i-ROS, i-MSDS, njll.
Custom Synthesis?Ingahlinzeka ngezinsizakalo zokwenziwa ngokwezifiso ukuze zilingane kangcono nezidingo zakho zocwaningo.
Imigomo Yokukhokha?I-invoyisi ye-Proforma izothunyelwa kuqala ngemva kokuqinisekiswa kwe-oda, kufakwe nemininingwane yethu yasebhange.Inkokhelo nge-T/T (Telex Transfer), PayPal, Western Union, njll.
I-4,4'-Bis(2-Bromoacetyl)biphenyl (CAS: 4072-67-7) iphakathi kwe-Daclatasvir Dihydrochloride (CAS: 1009119-65-6).
I-Daclatasvir Dihydrochloride (i-Daklinza) iyi-inhibitor ye-hepatitis C virus (HCV) NS5A ewusizo ekwelapheni i-genotype 3 ukutheleleka okungapheli kwe-hepatitis C.
Ngomhla zingama-24 kuJulayi, 2015, i-FDA yagunyaza umuthi ongalapheki we-hepatitis C (Bristol-Myers Squibb) ukuthi ukhangise.
Inqubo yokugunyaza i-FDA ye-Daklinza (Bristol-Myers Squibb) iye yashintshashintsha.Ike yenqatshwa yi-FDA, kodwa yagcina ivunyiwe maphakathi no-2015.I-FDA igunyaze inhlanganisela ye-Daklinza ne-Sofosbuvir yokwelapha iziguli ze-hepatitis C zohlobo 3.
Eqinisweni, ngaphambi nje kokugunyazwa kwe-FDA, i-Daklinza yayivunyelwe ukumakethwa eJapane, e-European Union naseNingizimu Korea nakwamanye amazwe.Ngo-2014, umkhakha wezempilo wase-Japan wagunyaza ukusetshenziswa kwe-Daklinza ne-Asunaprevir (Sunvepra) yokwelapha ukutheleleka kwe-genotype 1.I-European Union iphinde yagunyaza ukuthi i-Daclatasvir isetshenziswe ngokuhambisana neminye imithi ekwelapheni i-HCV genotypes 1, 2, 3 kanye no-4 ngo-2014. I-Daclatasvir iyi-complex inhibitor yokuqala ye-NS5A egunyazwe yi-European Union (EU).Uma isetshenziswa ngokuhlanganiswa nezinye izidakamizwa, uma iqhathaniswa nenhlanganisela yokwelapha ye-interferon ne-ribavirin ethatha amasonto angama-48, iba nesikhathi esifushane sokwelashwa (amaviki ayi-12 noma amaviki angama-24).
I-Daclathavir monotherapy ayinconyiwe, umthetho olandelwayo wamanje ojwayelekile uwukwelapha okuhlangene kwe-Dacastavir+ Sofosbuvir, okubonakala ngokusebenza kahle, i-SVR ephezulu, imiphumela engemihle emincane kanye nomjikelezo wokwelashwa omfushane omfushane kunezinye izinketho.
