I-Enzalutamide CAS 915087-33-1 Ubumsulwa >99.0% (HPLC)
I-Shanghai Ruifu Chemical Co., Ltd. ingumkhiqizi ohamba phambili we-Enzalutamide (CAS: 915087-33-1) enekhwalithi ephezulu.I-Ruifu Chemical inganikeza ukulethwa komhlaba wonke, intengo encintisanayo, isevisi enhle kakhulu, amanani amancane kanye nenqwaba etholakalayo.Thenga i-Enzalutamide (CAS: 915087-33-1),Please contact: alvin@ruifuchem.com
| Igama Lekhemikhali | I-Enzalutamide |
| Omqondofana | I-MDV-3100;I-MDV 3100;4--[3-[4-Cyano-3-(Trifluoromethyl))phenyl]-5,5-Dimethyl-4-Oxo-2-Thioxo-1-Imidazolidinyl]-2-Fluoro-N-Methylbenzamide |
| Isimo Sesitoko | Esitokweni, Amandla Okukhiqiza ama-50 kgs Ngenyanga |
| Inombolo ye-CAS | 915087-33-1 |
| I-Molecular Formula | I-C21H16F4N4O2S |
| Isisindo samangqamuzana | 464.44 g/mol |
| I-Melting Point | 198.0 ~ 200.0 ℃ |
| Ukuminyana | 1.49 |
| I-COA ne-MSDS | Iyatholakala |
| Umsuka | Shanghai, China |
| Ibhrendi | I-Ruifu Chemical |
| Izinto | Imininingwane | Imiphumela |
| Ukubukeka | Impushana Eqinile Emhlophe ukuya Kokumhlophe | Iyahambisana |
| Ukuhlanzeka / Indlela Yokuhlaziya | >99.0% (HPLC) | 99.57% |
| Amanzi nguKarl Fischer | <0.50% | 0.23% |
| Izinsalela ekushiseni | <0.10% | 0.06% |
| Izinsimbi Ezisindayo (Pb) | ≤20ppm | <10ppm |
| Izinto Ezihlobene | ||
| Ubukhulu.Ukungcola Okukodwa | <0.50% | <0.50% |
| Ukungcola Okuphelele | <1.00% | 0.43% |
| I-Infrared Spectrum | Ihambisana Nesakhiwo | Iyahambisana |
| 1H NMR Spectrum | Ihambisana Nesakhiwo | Iyahambisana |
| Isiphetho | Umkhiqizo uhloliwe futhi uthobela imininingwane enikeziwe | |
Iphakheji:Ibhodlela, isikhwama se-Aluminium foil, 25kg/Cardboard Drum, noma ngokwezidingo zekhasimende.
Isimo Sesitoreji:Gcina isiqukathi sivalwe ngokuqinile futhi usigcine endaweni epholile, eyomile (2~8℃) nengena umoya omuhle kude nezinto ezingahambelani.Vikela ekukhanyeni nakumswakama.
Ukuthumela:Zilethe emhlabeni wonke ngendiza, yi-FedEx/DHL Express.Nikeza ukulethwa okusheshayo nokuthembekile.
Indlela Yokuthenga?Sicela uxhumaneDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
Iminyaka engu-15 Yokuhlangenwe nakho?Sinesipiliyoni seminyaka engaphezu kwe-15 ekwakhiweni nasekuthumeleni kwamanye amazwe uhla olubanzi lwezinga eliphezulu lokuxhumanisa imithi noma amakhemikhali amahle.
Izimakethe Eziyinhloko?Thengisa emakethe yasekhaya, eNyakatho Melika, eYurophu, eNdiya, eKorea, eJapane, e-Australia, njll.
Izinzuzo?Ikhwalithi ephezulu, intengo ethengekayo, izinsizakalo ezichwepheshile nokusekelwa kobuchwepheshe, ukulethwa okusheshayo.
IkhwalithiIsiqiniseko?Isistimu yokulawula ikhwalithi eqinile.Imishini yobuchwepheshe yokuhlaziya ifaka i-NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, NOMA, KF, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, njll.
Amasampula?Imikhiqizo eminingi inikeza amasampula wamahhala wokuhlolwa kwekhwalithi, izindleko zokuthumela kufanele zikhokhelwe amakhasimende.
Ukuhlolwa Kwemboni?Wamukelekile ekucwaningweni kwemboni.Sicela wenze i-aphoyintimenti kusengaphambili.
I-MOQ?Ayikho i-MOQ.I-oda elincane liyamukeleka.
Isikhathi sokuthumela? Uma kungaphakathi kwesitoko, ukulethwa kwezinsuku ezintathu kuqinisekisiwe.
Ezokuthutha?By Express (FedEx, DHL), by Air, by Sea.
Amadokhumenti?Ngemuva kwenkonzo yokuthengisa: I-COA, i-MOA, i-ROS, i-MSDS, njll.
Custom Synthesis?Ingahlinzeka ngezinsizakalo zokwenziwa ngokwezifiso ukuze zilingane kangcono nezidingo zakho zocwaningo.
Imigomo Yokukhokha?I-invoyisi ye-Proforma izothunyelwa kuqala ngemva kokuqinisekiswa kwe-oda, kufakwe nemininingwane yethu yasebhange.Inkokhelo nge-T/T (Telex Transfer), PayPal, Western Union, njll.
I-Enzalutamide (i-CAS: 915087-33-1) iphikisana ne-androgen-receptor (AR) ene-IC50 ye-36 nM, evimbela i-androgens ekubopheni i-androgen receptor futhi ivimbele ukudluliselwa kwe-nuclear kanye nokuqashwa kwe-co-activator ye-ligand-receptor complex.I-Enzalutamide ikhonjisiwe futhi ukuthi yenza i-tumor cell apoptosis, futhi ayinawo umsebenzi we-agonist.I-Enzalutamide ikhandidethi ekwelapheni umdlavuza wendlala yesinye.I-Enzalutamide, iyisivimbeli sokusayina se-androgen receptor (AR) sesizukulwane sesibili.Iyakwazi ukuvimbela ukuboshwa kwama-androgens ku-AR, ukudluliselwa kwe-nuclear ye-AR, kanye nokuhlangana kwe-AR ne-DNA.Ngo-Agasti 2012, i-FDA yagunyaza i-Enzalutamide, imakethwa yi-Medivation kanye ne-Astellas Pharma US ukuze yolaphe umdlavuza wendlala yesinye we-metastatic castration-resistant (CRPC), ikakhulukazi lezo ziguli ezake zathola i-Docetaxel ngaphambilini.
