I-CAS 928672-86-0 Purity ≥99.0% (HPLC) API
Inombolo ye-CAS | 928672-86-0 |
Inombolo yeCAT | I-RF-API22 |
Isimo Sesitoko | Esitokweni, Isikali Sokukhiqiza Sifika Emakhulwini Amakhilogremu |
I-Molecular Formula | I-C24H27FO6S |
Isisindo samangqamuzana | 462.53 |
Ibhrendi | I-Ruifu Chemical |
Into | Imininingwane |
Ukubukeka | Impushana Emhlophe |
Ukuhlonza | I-HPLC/NMR |
Ukuncibilika | I-Soluble Kakhulu ku-Methanol;Incibilika ku-Ethanol, i-Acetonitrile;Incibilika Kancane Emanzini |
Ukuhlanzeka / Indlela Yokuhlaziya | ≥99.0% (HPLC) |
Ukungcola Ngamunye | ≤0.10% |
Ukungcola Okuphelele | ≤0.50% |
Izincibilikisi Ezisele | |
I-Methanol | ≤3000ppm |
I-Ethanol | ≤5000ppm |
I-acetonitrile | ≤400ppm |
I-Dichloromethane | ≤600ppm |
I-Ethyl Acetate | ≤5000ppm |
I-THF | ≤720ppm |
I-Toluene | ≤890ppm |
Izinga Lokuhlola | I-Chinese Pharmacopoeia (CP);I-Enterprise Standard |
Ukusetshenziswa | I-Active Pharmaceutical Ingredient (API);I-SGLT-2 inhibitors Type 2 Diabetes |
Iphakheji: Ibhodlela, isikhwama se-Aluminium foil, 25kg/Cardboard Drum, noma ngokwemfuneko yekhasimende
Isimo Sesitoreji:Gcina ezitsheni ezivaliwe endaweni epholile neyomile;Vikela ekukhanyeni, umswakama
Kuwumuthi wesigaba se-gliflozin noma i-subtype 2 sodium-glucose transport inhibitors (SGLT2) esetshenziselwa ukwelapha uhlobo lwesifo sikashukela sohlobo 2.Yasungulwa ngabakwaMitsubishi Tanabe Pharma futhi imakethwa ngaphansi kwelayisensi ngu-Janssen, ingxenye ye-Johnson & Johnson.Inesibopho okungenani esingu-90% sokumuncwa kabusha kweglucose ezinso.Ukuvimba lesi sithuthi kubangela ukuthi i-glucose yegazi iphume ngomchamo.NgoMashi 2013, ibe inhibitor yokuqala ye-SGLT2 ukuvunywa e-United States.To ukusho inzuzo, lesi sidakamizwa sisiza iziguli ukuba zinciphise ushukela wegazi ngaphandle kokwandisa amathuba okuthola isisindo inqobo nje uma kulandelwa ukudla okunempilo, okulinganiselayo nokuzivocavoca okuvamile.Ngaphezu kwalokho, Inethemba elibanzi ngenxa yemiphumela yayo ebalulekile ye-antiobesity kanye nemicimbi embalwa ye-hypoglycemic.