4-Chloro-6-Iodoquinazoline CAS 98556-31-1 Purity >98.0% (HPLC) Isithombe Esifakiwe

I-4-Chloro-6-Iodoquinazoline CAS 98556-31-1 Ubumsulwa >98.0% (HPLC)

Incazelo emfushane:

Igama Lekhemikhali: 4-Chloro-6-Iodoquinazoline

I-CAS: 98556-31-1

Ubumsulwa: >98.0% (HPLC)

Ukubukeka: Umhlaba Ophuzi ukuya Kokuphuzi-Onsundu

Iphakathi kweLapatinib / Lapatinib Ditosylate Monohydrate

Thintana: UDkt. Alvin Huang

Iselula/Wechat/WhatsApp: +86-15026746401

E-Mail: alvin@ruifuchem.com

Thumela i-imeyili kithi

Imininingwane Yomkhiqizo

Imikhiqizo Ehlobene

Omaka bomkhiqizo

Incazelo:

I-Shanghai Ruifu Chemical Co., Ltd. ingumkhiqizi ohamba phambili we-4-Chloro-6-Iodoquinazoline (CAS: 98556-31-1) enekhwalithi ephezulu.I-Ruifu Chemical inganikeza ukulethwa komhlaba wonke, intengo encintisanayo, isevisi enhle kakhulu, amanani amancane kanye nenqwaba etholakalayo.Thenga i-4-Chloro-6-Iodoquinazoline,Please contact: alvin@ruifuchem.com

I-Lapatinib Intermediates:

I-Lapatinib Base	I-CAS 231277-92-2
I-Lapatinib Ditosylate Monohydrate	I-CAS 388082-78-8
I-Sodium Methanesulfinate	I-CAS 20277-69-4
3-Chloro-4-(3-Fluorobenzyloxy)aniline	I-CAS 202197-26-0
2-Aminoethyl Methyl Sulfone Hydrochloride	I-CAS 104458-24-4
4-Chloro-6-Iodoquinazoline	I-CAS 98556-31-1
6-Iodo-4-Hydroxyquinazoline	I-CAS 16064-08-7
I-5-Formyl-2-Furanboronic Acid	I-CAS 27329-70-0
5-[4-[3-Chloro-4-(3-Fluorobenzyloxy)anilino]-6-Quinazolinyl]furan-2-Carboxaldehyde	I-CAS 231278-84-5

Chemical Properties:

Igama Lekhemikhali	4-Chloro-6-Iodoquinazoline
Omqondofana	6-Iodo-4-Chloroquinazoline
Isimo Sesitoko	Ku-Stock, Commercial Production
Inombolo ye-CAS	98556-31-1
I-Molecular Formula	I-C8H4ClIN2
Isisindo samangqamuzana	290.49 g/mol
I-Melting Point	175.0 ukuze 179.0 ℃
Ukuminyana	2.017±0.06 g/cm3
I-Refractive Index n20/D	1.739
Kuyazwela	Kuyazwela emoyeni
I-COA ne-MSDS	Iyatholakala
Umsuka	Shanghai, China
Ibhrendi	I-Ruifu Chemical

Imininingwane:

Izinto	Amazinga Wokuhlola	Imiphumela
Ukubukeka	Umhlaba Ophuzi Ukuya Kokuphuzi Okunsundu	Umhlaba Ophuzi Oyimpushana
I-Melting Point	175.0 ukuze 179.0 ℃	177.2℃
Ukulahlekelwa Ekumisweni	<1.00%	0.15%
Ukuhlanzeka / Indlela Yokuhlaziya	>98.0% (HPLC)	98.43%
1H NMR Spectrum	Ihambisana Nesakhiwo	Iyahambisana
Isiphetho	Umkhiqizo uhloliwe futhi uthobela imininingwane enikeziwe
Isicelo	Iphakathi kweLapatinib / Lapatinib Ditosylate Monohydrate

Iphakheji/Isitoreji/Ukuthumela ngomkhumbi:

Iphakheji:Ibhodlela eliFluorinated, isikhwama se-Aluminium foil, 25kg/Cardboard Drum, noma ngokwezidingo zekhasimende.
Isimo Sesitoreji:Gcina isitsha sivalwe ngokuqinile futhi usigcine endaweni epholile, eyomile futhi enomoya omuhle kude nezinto ezingahambelani.Vikela ekukhanyeni nakumswakama.
Ukuthumela:Zilethe emhlabeni wonke ngendiza, yi-FedEx/DHL Express.Nikeza ukulethwa okusheshayo nokuthembekile.

Izinzuzo:

Amandla Anele: Izinsiza ezanele kanye nochwepheshe

Isevisi Yobuchwepheshe: Isevisi yokuthenga yokuma eyodwa

Iphakheji le-OEM: Iphakheji yangokwezifiso kanye nelebula iyatholakala

Ukulethwa Okusheshayo: Uma kungaphakathi kwesitoko, ukulethwa kwezinsuku ezintathu kuqinisekisiwe

Impahla Ezinzile: Gcina isitoko esinengqondo

Ukusekelwa Kwezobuchwepheshe: Isixazululo sezobuchwepheshe siyatholakala

Isevisi Yokuhlanganisa Ngokwezifiso: Isukela kumagremu kuye kumakhilo

Ikhwalithi Ephezulu: Kusungulwe uhlelo oluphelele lokuqinisekisa ikhwalithi

I-FAQ:

Indlela Yokuthenga?Sicela uxhumaneDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
Iminyaka engu-15 Yokuhlangenwe nakho?Sinesipiliyoni seminyaka engaphezu kwe-15 ekwakhiweni nasekuthumeleni kwamanye amazwe uhla olubanzi lwezinga eliphezulu lokuxhumanisa imithi noma amakhemikhali amahle.
Izimakethe Eziyinhloko?Thengisa emakethe yasekhaya, eNyakatho Melika, eYurophu, eNdiya, eKorea, eJapane, e-Australia, njll.
Izinzuzo?Ikhwalithi ephezulu, intengo ethengekayo, izinsizakalo ezichwepheshile nokusekelwa kobuchwepheshe, ukulethwa okusheshayo.
IkhwalithiIsiqiniseko?Isistimu yokulawula ikhwalithi eqinile.Imishini yobuchwepheshe yokuhlaziya ifaka i-NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, NOMA, KF, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, njll.
Amasampula?Imikhiqizo eminingi inikeza amasampula wamahhala wokuhlolwa kwekhwalithi, izindleko zokuthumela kufanele zikhokhelwe amakhasimende.
Ukuhlolwa Kwemboni?Wamukelekile ekucwaningweni kwemboni.Sicela wenze i-aphoyintimenti kusengaphambili.
I-MOQ?Ayikho i-MOQ.I-oda elincane liyamukeleka.
Isikhathi sokuthumela? Uma kungaphakathi kwesitoko, ukulethwa kwezinsuku ezintathu kuqinisekisiwe.
Ezokuthutha?By Express (FedEx, DHL), by Air, by Sea.
Amadokhumenti?Ngemuva kwenkonzo yokuthengisa: I-COA, i-MOA, i-ROS, i-MSDS, njll.
Custom Synthesis?Ingahlinzeka ngezinsizakalo zokwenziwa ngokwezifiso ukuze zilingane kangcono nezidingo zakho zocwaningo.
Imigomo Yokukhokha?I-invoyisi ye-Proforma izothunyelwa kuqala ngemva kokuqinisekiswa kwe-oda, kufakwe nemininingwane yethu yasebhange.Inkokhelo nge-T/T (Telex Transfer), PayPal, Western Union, njll.

98556-31-1 - Isicelo:

I-4-Chloro-6-Iodoquinazoline (i-CAS: 98556-31-1) iphakathi ekuhlanganiseni kwe-Lapatinib (CAS: 231277-92-2) / Lapatinib Ditosylate Monohydrate (CAS: 388082-78-8).
I-Lapatinib isidakamizwa esisha esihloselwe ukwelapha umdlavuza webele esakhiwe futhi sakhiqizwa yi-GlaxoSmithKline, esigunyazwe yi-US Food and Drug Administration ngo-March 13, 2007. Inkomba evunyelwe okwamanje ihlanganiswe ne-capecitabine yomdlavuza webele othuthukile noma we-metastatic, kanye neziguli zomdlavuza webele. kumele zelashwe ngeminye imithi yomugqa wokuqala.Igama layo lokuhweba e-United States yiTykerb.Ngomhla ziyi-14 kuZibandlela wezi-2007, i-European Medicines Agency (EMEA) yagunyaza ukufakwa kuhlu kweLapatinib eYurophu ngaphansi kwegama lokuhweba elithi Tyverb.Ukwelashwa okuhloswe ngamangqamuzana omdlavuza webele kubhekisela ekwelapheni ama-oncogenes kanye nemikhiqizo yokukhuluma ehlobene ehlobene nokuvela nokukhula komdlavuza webele.Izidakamizwa eziqondiswe kumamolekyuli zivimbela noma zibulale amaseli wesimila ngokuvimbela ukudluliselwa kwesignali kumaseli wesimila noma amaseli ahlobene ukuze alawule izinguquko ekukhulumeni kofuzo lweseli.I-Lapatinib iyi-molecule yomlomo encane ye-epidermal growth factor tyrosine kinase inhibitor.Ukuhlolwa komtholampilo kubonise ukuthi ezigulini zomdlavuza webele we-HER2 eziye zaqala ukumelana ne-Roche's Herceptin (Herceptin), i-Lapatinib inomphumela omuhle womtholampilo.Ukuhlolwa kwe-in vitro, i-Lapatinib ibe nomthelela omkhulu wokuvimbela ukukhula emigqeni yamaseli omdlavuza webele we-Her-2.Ezivivinyweni zeSigaba I zomdlavuza webele othuthukisiwe one-Her-2 overexpression, i-Lapatinib nayo inezinga eliphezulu elisebenzayo futhi ayinakho ukumelana ne-Herceptin (trastuzumab).Ngenxa yokuthi ukwakheka kwayo kuyi-molecule encane, ngokungafani ne-Herceptin (trastuzumab), ingangena kumgoqo wegazi nobuchopho futhi ibe nomthelela othile wokwelapha kumetastasis yobuchopho yomdlavuza webele.