I-Caspofungin Acetate Cancidas CAS 179463-17-3 API Factory High Purity
Umkhiqizi onokuhlanzeka Okuphezulu kanye Nekhwalithi Ezinzile
Igama Lekhemikhali: I-Caspofungin Acetate
I-CAS: 179463-17-3
Ikhwalithi ephezulu ye-API, Ukukhiqiza Kwezentengiso
Igama Lekhemikhali | I-Caspofungin Acetate |
Omqondofana | I-Cancidas;I-MK-0991 Acetate;L-743872 Acetate |
Inombolo ye-CAS | 179463-17-3 |
Inombolo yeCAT | I-RF-API58 |
Isimo Sesitoko | Esitokweni, Isikali Sokukhiqiza Sifika Emakhulwini Amakhilogremu |
I-Molecular Formula | C52H88N10O15·2C2H4O2 |
Isisindo samangqamuzana | 1213.42 |
I-Melting Point | > 197℃ |
Ibhrendi | I-Ruifu Chemical |
Into | Imininingwane |
Ukubukeka | Impushana Emhlophe noma Ecishe Emhlophe |
Ukuhlonza IR | IR: I-Spectrum Yesampula Yokuhlola kufanele ihambisane naleyo Yezinga Lereferensi ye-Caspofungin Acetate |
Ukuhlonza HPLC | I-HPLC: Isikhathi sokugcina sesiqongo esiphezulu esitholwa esixazululweni sokuhlola kufanele sihambisane nalesi esitholwe esixazululweni esijwayelekile, njengokuhlola ku-Assay. |
Ukucaca Nombala | Isixazululo kufanele sicace futhi singabi nombala |
Ukuzungezisa okuqondile | -102.0° ~ -108.0° |
pH | 5.0~7.0 |
Amanzi | ≤10.0% |
Izinto Ezihlobene I | (Kusisekelo samahhala se-Anhydrous ne-Acetic) |
Ukungcola A | ≤0.10% |
Ukungcola B | ≤0.10% |
Ukungcola D | ≤0.30% |
Ukungcola E | ≤0.10% |
Ukungcola Okungashiwongo F | ≤0.10% |
Ukungcola Okungashiwongo G | ≤0.10% |
I-Pneumocandin B0 | ≤0.10% |
Ukungcola Okungaziwa Okukodwa | ≤0.10% |
Ukungcola Okuphelele | ≤1.0% |
Izinto Ezihlobene II | ≤0.10% |
Izincibilikisi Ezisele | |
I-Ethyl Acetate | ≤5000ppm |
I-Ethanol | ≤5000ppm |
I-Methanol | ≤5000ppm |
I-acetonitrile | ≤410ppm |
I-Tetrahydrofuran | ≤720ppm |
Okuqukethwe kwe-Acetic Acid | 9.0%~11.0% (Ibalwe Ngokusekelwe I-Anhydrous) |
I-Ethylendiamine | ≤0.10% |
Izinsalela ekushiseni | ≤0.10% |
Izinsimbi Ezisindayo (njenge-Pb) | ≤10ppm |
Indlela Yokuhlola / Yokuhlaziya | 97.0%~102.0% (Kusisekelo Esingenayo I-Anhydrous kanye Ne-Solvent) |
Izinga Lokuhlola | I-Enterprise Standard |
Ukusetshenziswa | I-Active Pharmaceutical Ingredient (API) |
Iphakheji: Ibhodlela, isikhwama se-Aluminium foil, isigubhu seCardboard, 25kg/Drum, noma ngokwezidingo zekhasimende.
Isimo Sesitoreji:Gcina ezitsheni ezivaliwe endaweni epholile neyomile;Vikela ekukhanyeni, umswakama kanye nezinambuzane.
I-Caspofungin Acetate (i-CAS: 179463-17-3) iyisidakamizwa se-lipopeptide antifungal.I-Caspofungin acetate yomjovo yavunywa ekuqaleni i-FDA e-USA, kanye ne-EMEA e-Europe, ngo-2001. I-Caspofungin Acetate iwuketshezi oluncibilikayo lwamanzi, oluzinzile, lwe-aza-substituted semisynthetic lwe-Pneumocandin B, umkhiqizo wokuvutshelwa wesikhunta i-Zalerion arboricola.I-lipopeptide caspofungin, ivimbela ukuhlanganiswa kwe-1,3-beta- D-glucans ekhona kuphela odongeni lwamaseli we-fungal, okuholela ekuhlaziyweni okuqondile kwamaseli e-pathogenic.Inhlanganisela iyi-fungicidal esikhundleni se-fungistatic, isici esingajwayelekile phakathi kwama-antifungal agents.I-Caspofungin yayivame ukusebenza kakhulu kune-amphotericin B, i-flucytosine, i-fluconazole ne-itraconazole ngokumelene nezinhlobo ze-Candida.