I-Cisatracurium Besylate CAS 96946-42-8 Assay 95.0%~102.0% Ikhwalithi ephezulu ye-API Factory

Incazelo emfushane:

Igama Lekhemikhali: Cisatracurium Besylate

I-CAS: 96946-42-8

Ukubukeka: Impushana Emhlophe noma Cishe Emhlophe, Ayinaphunga

I-Assay: 95.0%~102.0% (C65H82N2O18S2 ngokomisiwe)

I-Synthetic Non-Depolarizing Muscle Relaxants

I-API, Ikhwalithi Ephezulu, Ukukhiqizwa Kwezohwebo

Inquiry: alvin@ruifuchem.com


Imininingwane Yomkhiqizo

Imikhiqizo Ehlobene

Omaka bomkhiqizo

Incazelo:

Umkhiqizi onokuhlanzeka Okuphezulu kanye Nekhwalithi Ezinzile
Igama Lekhemikhali: Cisatracurium Besylate
I-CAS: 96946-42-8
Ikhwalithi ephezulu ye-API, Ukukhiqiza Kwezentengiso

Chemical Properties:

Igama Lekhemikhali I-Cisatracurium Besylate
Inombolo ye-CAS 96946-42-8
Inombolo yeCAT I-RF-API13
Isimo Sesitoko Esitokweni, Isikali Sokukhiqiza Sifinyelela Kumathani
I-Molecular Formula I-C53H72N2O12.2C6H5O3S
Isisindo samangqamuzana 1243.49
I-Melting Point 90.0~93.0℃
Isimo Sokuthumela Ngaphansi Kwezinga Lokushisa Le-Ambient
Ibhrendi I-Ruifu Chemical

Imininingwane:

Into Imininingwane
Ukubukeka Impushana Emhlophe noma Ecishe Emhlophe, Ayinaphunga, I-Hygroscopic Kancane
Ukuncibilika Incibilika ngokukhululekile ku-dichloromethane, i-acetonitrile, inyibilika kancane emanzini
Ukuzungezisa okuqondile -35.0° ukuya -45.0° (C=10mg/ml, 0.1mg/ml benzene sulfonic acid)
Ukuhlonza Chaza nge-dilute hydrochoric acid, i-dropwise dilute bismuth potassium iodide TS, imvula ephuzi izokhiqizwa
Ukuhlonza 1. I-HPLC ;2. I-IR
Isivivinyo 95.0~102.0% (C65H82N2O18S2 ngokomisiwe)
pH 3.5 kuye ku-5.0
Ukucaca Nombala Wesixazululo Kufanele Icace futhi Ingabi Nambala
Ukulahlekelwa Ekumisweni ≤2.0%
Insalela ekushiseni ≤0.20%
Izinsimbi Ezisindayo ≤20ppm
I-Trans-Trans Isomer ≤0.50%
I-Cis-Trans Isomer ≤0.50%
Ama-mono-quaternaries ≤1.50%
Noma yikuphi Ukungcola Komuntu Ngamunye ≤1.50%
Ukungcola Okuphelele ≤5.0%
I-Optical Isomer SS-Isomer ≤1.50%
I-Optical Isomer RS- Isomer ≤1.00%
I-sulfate ≤50ppm
I-Ethyl ≤0.50%
I-acetone ≤0.50%
I-Methanol ≤0.3%
I-Dichloromethane ≤0.06%
I-acetonitrile ≤0.041%
I-methylbenzene ≤0.089%
I-Residual Solvents i-Acetonitrile ≤410ppm
Izinga Lokuhlola I-Chinese Pharmacopoeia (CP)
Ukusetshenziswa I-Active Pharmaceutical Ingredient (API)

Iphakheji nesitoreji:

Iphakheji: Ibhodlela, isikhwama se-Aluminium foil, isigubhu seCardboard, 25kg/Drum, noma ngokwezidingo zekhasimende.

Isimo Sesitoreji:Gcina ezitsheni ezivaliwe endaweni epholile neyomile;Vikela ekukhanyeni, umswakama kanye nezinambuzane.

Izinzuzo:

1

I-FAQ:

12

Isicelo:

I-Cisatracurium Besylate (i-CAS 96946-42-8) iwuhlobo lwe-benzene sulfonate usawoti we-atracurium.Iwuhlobo lweziphumuli zokwenziwa zokwenziwa ezingezona-depolarizing ezinendima yazo efana ne-tubocurarine.Umthamo wokwelapha awuthinti inhliziyo, isibindi kanye nokusebenza kwezinso.Futhi ayinayo impahla yokuqongelela.Kungase futhi kubangele ukukhululwa kwe-histamine uma isetshenziswa ngemithamo emikhulu.Ukuze uthole ukuphumula kwemisipha noma ukulawula ukuphefumula okudingekayo ekuhlinzeni, uma kuqhathaniswa nezidakamizwa zamanje zomtholampilo ezinkulu eziphumuza imisipha, i-cisatracurium besylate ayifakwanga i-metabolized ngesibindi noma izinso, futhi inokusimama kwenhliziyo;umphumela wawo wokuphumula kwemisipha unamandla izikhathi ezingu-3 njenge-atracurium ngaphandle kwemiphumela emibi yenhliziyo.I-Cisatracurium besylate isetshenziswa ngokuyinhloko ku-anesthesia ejwayelekile, futhi ingasetshenziswa kabanzi ekungeneni, ekwelapheni ukungasebenzi kahle kwesibindi nezinso, okusetshenziselwa ukuhlinzwa kwenhliziyo nemithambo yegazi kanye neziguli ezikhulile nezezingane.Uma kuqhathaniswa ne-atracurium, lo mkhiqizo awunayo imiphumela emibi encike kumthamo wokukhishwa kwe-histamine;Nokho, okubi ukuthi iziguli ezinokukhubazeka kwesibindi nezinso kufanele zilawule ngokuqapha.Kusukela ngo-1996 ngokokuqala ngqa lapho lesi sidakamizwa singena emakethe e-UK, amazwe angaphandle asebenzise kancane kancane ukuze athathe indawo ye-vecuronium ne-atracurium njengendlela evamile yokuphumula kwemisipha yomtholampilo.

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