I-Citicoline Sodium Salt Hydrate CAS 33818-15-4 Assay ≥98.0% High Purity
Umkhiqizi onokuhlanzeka Okuphezulu kanye Nekhwalithi Ezinzile
Igama Lekhemikhali: I-Citicoline Sodium
CAS: 33818-15-4
Ikhwalithi Ephezulu, Ukukhiqizwa Kwezohwebo
Igama Lekhemikhali | I-Citicoline sodium |
Omqondofana | I-CDPC;I-CDP-Choline;I-Cytidine 5'-Diphosphocholine Sodium Salt |
Inombolo ye-CAS | 33818-15-4 |
Inombolo yeCAT | I-RF-API09 |
Isimo Sesitoko | Esitokweni, Isikali Sokukhiqiza Sifinyelela Kumathani |
I-Molecular Formula | I-C14H27N4NaO11P2 |
Isisindo samangqamuzana | 512.32 |
I-Melting Point | 259.0~268.0℃ (dec.) |
Ukuncibilika kwamanzi | Incibilika Emanzini |
Isimo Sokuthumela | Ngaphansi Kwezinga Lokushisa Le-Ambient |
Ibhrendi | I-Ruifu Chemical |
Into | Imininingwane |
Ukubukeka | I-Crystalline Emhlophe noma I-Crystalline Powder, Ayinaphunga |
Ukuncibilika | Incibilika Ngokukhululekile emanzini, ayincibiliki ku-ethanol, ku-acetone naku-chloroform |
Ukuhlonza | Umbala wokusabela kwesixazululo ubuwukusabela okuhle |
Ukuhlonza | Isikhathi sokugcinwa kwesilinganiso esiphezulu sesixazululo sesampula kufanele sihambisane naleso sezinga lesithenjwa. |
Ukuhlonza | I-spectrum yokumuncwa kwe-infrared ihambisana ne-spectrum yereferensi |
Ukuhlonza | Isixazululo se-aquous siveza isici sokusabela sosawoti we-sodium |
Ukucaca kanye Nombala Wesixazululo | Kufanele Icace futhi Ingabi Nambala |
Ama-Chloride | ≤0.05% |
Usawoti we-ammonium | ≤0.05% |
Insimbi | ≤0.01% |
I-Phosphate | ≤0.10% |
Ukulahlekelwa Ekumisweni | ≤6.0% |
Izinsimbi Ezisindayo | ≤0.0005% |
I-Arsenic | ≤0.0001% |
Ama-bacterium Endotoxins | ≤0.30 EU/mg |
Isamba Sesibalo Samagciwane | ≤1000cfu/g |
Yeast & Molds | ≤100cfu/g |
E.Coli | Akutholwanga |
5'-CMP | ≤0.30% |
Okunye ukungcola Okulula | ≤0.20% |
Okunye Ukungcola Okuphelele | ≤0.70% |
I-Residual Solvent Methanol | ≤0.30% |
I-Residual Solvent Ethanol | ≤0.50% |
I-Residual Solvent Acetone | ≤0.50% |
Ubumsulwa | ≥99.5% (I-Citicoline Sodium, Ibalwa ngesisekelo esomisiwe) |
Izinga Lokuhlola | I-Chinese Pharmacopoeia (None-Sterile APIS) |
Ukusetshenziswa | I-API;Pharmaceutical Intermediates |
Iphakheji: Ibhodlela, isikhwama se-Aluminium foil, isigubhu seCardboard, 25kg/Drum, noma ngokwezidingo zekhasimende.
Isimo Sesitoreji:Gcina ezitsheni ezivaliwe endaweni epholile neyomile;Vikela ekukhanyeni, umswakama kanye nezinambuzane.
I-Citicoline iyi-nucleic acid derivatives, uGeiger wathola ukuthi i-citicoline ingabuyisela ukulimala kobuchopho ekuhlolweni kwezilwane ngo-1956. Ucwaningo lukaKennedy lwaqinisekisa ukuthi i-citicoline ingenza ukululama kokulimala kobuchopho ngo-1957. Yabhaliswa e-China ngo-1988, futhi okwamanje iyona ethengiswa kakhulu. izidakamizwa phakathi kwezifo zobuchopho zomtholampilo.Idlala indima ebalulekile ekwakhiweni kwe-lecithin, ngokukhuthaza ukuhlanganiswa kwe-lecithin nokwenza ngcono ukusebenza kobuchopho.Ukuhlola kubonisa ukuthi i-citicoline ingathuthukisa amazinga e-norepinephrine ne-dopamine ohlelweni lwezinzwa olumaphakathi, ngaleyo ndlela ingakwazi ukwelapha isifo sobuchopho, ukulimala kobuchopho okubuhlungu kanye nokukhubazeka kwengqondo okubangelwa izizathu ezihlukahlukene, futhi ayikho imiphumela emibi esobala.
I-Citicoline sodium ingathuthukisa umsebenzi wokubunjwa kwe-reticular stem reticular, ikakhulukazi uhlelo olukhulayo lwe-reticular activating oluhlotshaniswa nokuqaphela komuntu;ukuthuthukisa umsebenzi we-pyramidal system;vimbela umsebenzi wesistimu yangaphandle ye-cone, futhi ikhuthaza ukubuyiswa komsebenzi wesistimu.Ukuze ukwelashwa kwe-sequelae yokulimala kobuchopho okubuhlungu kanye nengozi ye-cerebral vascular ebangelwa isimiso sezinzwa, ingasetshenziswa futhi ekwelapheni isifo sika-Parkinson, ukuwohloka komqondo we-senile kunomphumela othile;ekwelapheni izifo zenhliziyo kanye ne-cerebrovascular;ibuye ibe nomthelela othile wokulwa nokuguga, ukuthuthukisa ukufunda nokukhumbula.