I-Cyano-Irbesartan CAS 138401-24-8 Ubumsulwa >98.0% (HPLC) I-Irbesartan Intermediate Factory

Incazelo emfushane:

Igama Lekhemikhali: I-Cyano-Irbesartan

I-CAS: 138401-24-8

Ubumsulwa: >98.0% (HPLC)

Ukubukeka: Impushana Emhlophe Ukuya Kucishe Emhlophe kuya kuCrystal

I-Irbesartan emaphakathi (CAS: 138402-11-6)

Ikhwalithi Ephezulu, Ukukhiqizwa Kwezohwebo

E-Mail: alvin@ruifuchem.com


Imininingwane Yomkhiqizo

Imikhiqizo Ehlobene

Omaka bomkhiqizo

Incazelo:

Chemical Properties:

Igama Lekhemikhali I-Cyano-Irbesartan
Omqondofana I-Cyano-Irbesartan;I-Irbesartan Cyano Ukungcola;I-Irbesartan Hydrocarbon;Ukungcola kwe-Irbesartan 6;2-Butyl-3-[[2'-cyano-[1,1'-biphenyl]-4-yl]methyl]-1,3-diazaspiro[4,4]non-1-en-4-one;4'-[(2-Butyl-4-oxo-1,3-diazaspiro[4,4]non-1-en-3-yl)methyl]-[1,1'-biphenyl]-2-carbonitrile
Inombolo ye-CAS 138401-24-8
Inombolo yeCAT I-RF-PI1892
Isimo Sesitoko Esitokweni, Isikali Sokukhiqiza Sifinyelela Kumathani
I-Molecular Formula I-C25H27N3O
Isisindo samangqamuzana 385.51
Ukuminyana 1.15
I-Solubility (I-Soluble in) I-Methanol
Ibhrendi I-Ruifu Chemical

Imininingwane:

Into Imininingwane
Ukubukeka Impushana Emhlophe Kuya Kucishe Emhlophe kuya kuCrystal
Ukuhlanzeka / Indlela Yokuhlaziya >98.0% (HPLC)
Ubumsulwa >97.0% (Ngenani leNitrojeni)
I-Melting Point 91.0 ukuze 95.0℃
Ukulahlekelwa Ekumisweni <1.00%
Ukungcola Okukodwa <1.00%
Izinsimbi Ezisindayo <20ppm
I-Infrared Spectrum Ivumelana Nesakhiwo
Izinga Lokuhlola I-Enterprise Standard
Ukusetshenziswa Okumaphakathi / Ukungcola kwe-Irbesartan (CAS: 138402-11-6)

Iphakheji nesitoreji:

Iphakheji: Ibhodlela, isikhwama se-Aluminium foil, 25kg/Cardboard Drum, noma ngokwemfuneko yekhasimende

Isimo Sesitoreji:Gcina ezitsheni ezivaliwe endaweni epholile neyomile;Vikela ekukhanyeni nakumswakama

Izinzuzo:

1

I-FAQ:

Isicelo:

I-Cyano-Irbesartan (i-CAS: 138401-24-8) iwukungcola okumaphakathi noma okuphakathi kwe-Irbesartan (CAS: 138402-11-6).I-Irbesartan iyi-angiotensin II (i-Angiotensin II, i-Ang II) inhibitor yama-receptor.I-Angiotensin II receptors ihlukaniswe yaba izinhlobo ezimbili: i-AT1 ne-AT2.I-Irbesartan ivimba ngokukhetha isamukeli se-AT1 se-AnglI.Ingavimbela ukuguqulwa kwe-Ang ibe yi-Ang, ingaphikisa ngokukhethekile i-angiotensin-converting enzyme 1 receptor (AT1).Umthelela ophikisayo ku-AT1 uphindwe izikhathi ezingama-8500 kune-AT2.Ingavimbela ngokukhetha ukubopha kwe-Ang ne-AT1 receptor ngokusebenzisa i-Inhibit vasoconstriction kanye nokukhululwa kwe-aldosterone, okuholela kumphumela we-hypotensive.Lo mkhiqizo awuvimbeli i-angiotensin converting enzyme (ACE), i-renin, amanye ama-hormone receptors, futhi awuvimbeli iziteshi ze-ion ezihlobene nokulawulwa komfutho wegazi kanye nebhalansi ye-sodium.I-Irbesartan inganciphisa nokulungiswa kabusha kukagesi kwe-myocardium, ngaleyo ndlela yehlise izinga lokufa kweziguli ezinomfutho wegazi ophakeme.Njengamanje isidakamizwa esisebenza kahle kakhulu ekwelapheni umfutho wegazi ophakeme kanye nezifo zenhliziyo.

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