I-Cyano-Irbesartan CAS 138401-24-8 Ubumsulwa >98.0% (HPLC) I-Irbesartan Intermediate Factory
I-Ruifu Chemical Supply Irbesartan Intermediates:
I-Irbesartan CAS 138402-11-6
I-Cyano-Irbesartan CAS 138401-24-8
I-Trityl Irbesartan CAS 138402-10-5
I-TTBB CAS 124750-51-2
I-Irbesartan Side Chain Hydrochloride CAS 151257-01-1
Igama Lekhemikhali | I-Cyano-Irbesartan |
Omqondofana | I-Cyano-Irbesartan;I-Irbesartan Cyano Ukungcola;I-Irbesartan Hydrocarbon;Ukungcola kwe-Irbesartan 6;2-Butyl-3-[[2'-cyano-[1,1'-biphenyl]-4-yl]methyl]-1,3-diazaspiro[4,4]non-1-en-4-one;4'-[(2-Butyl-4-oxo-1,3-diazaspiro[4,4]non-1-en-3-yl)methyl]-[1,1'-biphenyl]-2-carbonitrile |
Inombolo ye-CAS | 138401-24-8 |
Inombolo yeCAT | I-RF-PI1892 |
Isimo Sesitoko | Esitokweni, Isikali Sokukhiqiza Sifinyelela Kumathani |
I-Molecular Formula | I-C25H27N3O |
Isisindo samangqamuzana | 385.51 |
Ukuminyana | 1.15 |
I-Solubility (I-Soluble in) | I-Methanol |
Ibhrendi | I-Ruifu Chemical |
Into | Imininingwane |
Ukubukeka | Impushana Emhlophe Kuya Kucishe Emhlophe kuya kuCrystal |
Ukuhlanzeka / Indlela Yokuhlaziya | >98.0% (HPLC) |
Ubumsulwa | >97.0% (Ngenani leNitrojeni) |
I-Melting Point | 91.0 ukuze 95.0℃ |
Ukulahlekelwa Ekumisweni | <1.00% |
Ukungcola Okukodwa | <1.00% |
Izinsimbi Ezisindayo | <20ppm |
I-Infrared Spectrum | Ivumelana Nesakhiwo |
Izinga Lokuhlola | I-Enterprise Standard |
Ukusetshenziswa | Okumaphakathi / Ukungcola kwe-Irbesartan (CAS: 138402-11-6) |
Iphakheji: Ibhodlela, isikhwama se-Aluminium foil, 25kg/Cardboard Drum, noma ngokwemfuneko yekhasimende
Isimo Sesitoreji:Gcina ezitsheni ezivaliwe endaweni epholile neyomile;Vikela ekukhanyeni nakumswakama
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I-Cyano-Irbesartan (i-CAS: 138401-24-8) iwukungcola okumaphakathi noma okuphakathi kwe-Irbesartan (CAS: 138402-11-6).I-Irbesartan iyi-angiotensin II (i-Angiotensin II, i-Ang II) inhibitor yama-receptor.I-Angiotensin II receptors ihlukaniswe yaba izinhlobo ezimbili: i-AT1 ne-AT2.I-Irbesartan ivimba ngokukhetha isamukeli se-AT1 se-AnglI.Ingavimbela ukuguqulwa kwe-Ang ibe yi-Ang, ingaphikisa ngokukhethekile i-angiotensin-converting enzyme 1 receptor (AT1).Umthelela ophikisayo ku-AT1 uphindwe izikhathi ezingama-8500 kune-AT2.Ingavimbela ngokukhetha ukubopha kwe-Ang ne-AT1 receptor ngokusebenzisa i-Inhibit vasoconstriction kanye nokukhululwa kwe-aldosterone, okuholela kumphumela we-hypotensive.Lo mkhiqizo awuvimbeli i-angiotensin converting enzyme (ACE), i-renin, amanye ama-hormone receptors, futhi awuvimbeli iziteshi ze-ion ezihlobene nokulawulwa komfutho wegazi kanye nebhalansi ye-sodium.I-Irbesartan inganciphisa nokulungiswa kabusha kukagesi kwe-myocardium, ngaleyo ndlela yehlise izinga lokufa kweziguli ezinomfutho wegazi ophakeme.Njengamanje isidakamizwa esisebenza kahle kakhulu ekwelapheni umfutho wegazi ophakeme kanye nezifo zenhliziyo.
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