I-α-Cyclodextrin (α-CD) I-CAS 10016-20-3 I-Excipients Yemithi
I-Ruifu Chemical ingumkhiqizi ohamba phambili we-α-Cyclodextrin (α-CD) (CAS: 10016-20-3) enekhwalithi ephezulu.I-Ruifu Chemical ihlinzeka nge-pharma grade cyclodextrins, izithasiselo zemithi.I-Ruifu Chemical inganikeza ukulethwa komhlaba wonke, amanani amancane futhi ngobuningi atholakalayo.Thenga i-α-Cyclodextrin,Please contact: alvin@ruifuchem.com
Igama Lekhemikhali | I-α-Cyclodextrin |
Omqondofana | α-CD;C;I-Alfadex;i-alpha-Dextrin;i-α-Dextrin;I-Cyclohexapentylose;I-Cavamax W6;I-Schardinger α-Dextrin;α-Schardinger Dextrin;Schardinger alpha-Dextrin;I-Cyclomaltohexaose;I-Cyclohexaamylose |
Isimo Sesitoko | Ku-Stock, Commercial Production |
Inombolo ye-CAS | 10016-20-3 |
I-Molecular Formula | C |
Isisindo samangqamuzana | g/mol |
I-Melting Point | >278℃(dec.) (lit.) |
Iphuzu elibilayo | ℃ |
I-Flash Point | ℃ |
Ukuminyana | |
I-Refractive Index n20/D | 1 |
Kuyazwela | I-Hygroscopic.Izwela Umoya, Izwela Ukukhanya, Izwela Umswakama |
Ukuncibilika kwamanzi | Incibilika Emanzini |
Ukuncibilika | Incibilika phakathi |
Ukuzinza | Izinzile.Okuvuthayo.Akuhambisani Ne-Ejenti Ye-oxidizing Eqinile. |
I-COA ne-MSDS | Iyatholakala |
Isampula yamahhala | Iyatholakala |
Umsuka | Shanghai, China |
Isigaba | Ama-Excipients Ezemithi;Izithasiselo Zokudla |
Ibhrendi | I-Ruifu Chemical |
Izinto | Imininingwane | Imiphumela |
Ukubukeka | Impushana emhlophe noma ecishe ibe mhlophe noma eyiCrystalline Powder | Kuyavumelana |
Ukuncibilika | Incibilika Ngokukhululekile Emanzini naku-Propylene Glycol, Ayincibiliki ku-Ethanol naku-Methylene Chloride | Kuyavumelana |
ukuthuthukiswa kwe-HPLC | Isikhathi sokugcina sesiqongo esikhulu sesixazululo sesampula sihambisana nesixazululo esijwayelekile. | Kuyavumelana |
Isixazululo Sokuhlola I-Iodine | Imvula Ephuzi Ngokunsundu Kwakhiwe | Kuyavumelana |
Isivivinyo | 98.0%~101.0% (Ibalwe Ngesisekelo Esomile) | 100.0% |
Ukuzungezisa Okuthile [a]20/D | +147.0° ukuya ku-+152.0°(C=1 ku-H2O) (Calcd. ku-Anh. Substance) | +148.2° |
Ukucaca Nombala Wesixazululo | Isixazululo samanzi esingu-10mg/ml sicacile futhi asinambala | Kuyavumelana |
Umkhawulo Wezinto Ezimunca Ukukhanya | ≤0.10 (230 nm~350 nm) ≤0.05 (350 nm~750 nm) | Kuyavumelana |
Ukunqunywa kwamanzi | ≤11.0% | 9.9% |
Izinsalela ekushiseni | ≤0.10% | 0.07% |
Izinsimbi Ezisindayo | ≤5ppm | <5ppm |
Usawoti we-Arsenic (As) | ≤1.3ppm | <1.3ppm |
Ukunciphisa Ushukela | ≤0.20% | 0.16% |
Izinto Ezihlobene | ||
I-Betadex Cyclodextrin | ≤0.25% | N/D |
I-Gamma Cyclodextrin | ≤0.25% | N/D |
Ezinye Izinto Ezihlobene | ≤0.50% | N/D |
pH | 5.0~8.0 | 6.2 |
Ukuhlolwa kweMicrobiological | ||
Isamba sezibalo ze-Aerobic Microbial | ≤1000cfu/g | 30cfu/g |
Isamba Sesikhunta & Imvubelo Ibala | ≤50cfu/g | <50cfu/g |
Escherichia Coli | Akekho | Akekho |
I-Salmonella | Akekho | Akekho |
I-Infrared Spectrum | Ivumelana Nesakhiwo | Kuyavumelana |
Izinga Lokuhlola | I-USP41-NF36 |
Iphakheji:0.5kg//bag, 1kg/bag, 2kg/bag, 10kg/bag, 25kg/Drum, noma ngokuvumelana nemfuneko yekhasimende.
Isimo Sesitoreji:Gcina isitsha sivalwe ngokuqinile futhi usigcine endaweni epholile, eyomile futhi enomoya omuhle kude nezinto ezingahambelani.Vikela ekukhanyeni nakumswakama.Akuhambisani nama-oxidizing agents aqinile.
Ukuthumela:Zilethe emhlabeni wonke ngendiza, yi-FedEx/DHL Express.Nikeza ukulethwa okusheshayo nokuthembekile.
Indlela Yokuthenga?Sicela uxhumaneDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
Iminyaka engu-15 Yokuhlangenwe nakho?Sinesipiliyoni seminyaka engaphezu kwe-15 ekwakhiweni nasekuthumeleni kwamanye amazwe uhla olubanzi lwezinga eliphezulu lokuxhumanisa imithi noma amakhemikhali amahle.
Izimakethe Eziyinhloko?Thengisa emakethe yasekhaya, eNyakatho Melika, eYurophu, eNdiya, eKorea, eJapane, e-Australia, njll.
Izinzuzo?Ikhwalithi ephezulu, intengo ethengekayo, izinsizakalo ezichwepheshile nokusekelwa kobuchwepheshe, ukulethwa okusheshayo.
IkhwalithiIsiqiniseko?Isistimu yokulawula ikhwalithi eqinile.Imishini yobuchwepheshe yokuhlaziya ifaka i-NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, NOMA, KF, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, njll.
Amasampula?Imikhiqizo eminingi inikeza amasampula wamahhala wokuhlolwa kwekhwalithi, izindleko zokuthumela kufanele zikhokhelwe amakhasimende.
Ukuhlolwa Kwemboni?Wamukelekile ekucwaningweni kwemboni.Sicela wenze i-aphoyintimenti kusengaphambili.
I-MOQ?Ayikho i-MOQ.I-oda elincane liyamukeleka.
Isikhathi sokuthumela? Uma kungaphakathi kwesitoko, ukulethwa kwezinsuku ezintathu kuqinisekisiwe.
Ezokuthutha?By Express (FedEx, DHL), by Air, by Sea.
Amadokhumenti?Ngemuva kwenkonzo yokuthengisa: I-COA, i-MOA, i-ROS, i-MSDS, njll.
Custom Synthesis?Ingahlinzeka ngezinsizakalo zokwenziwa ngokwezifiso ukuze zilingane kangcono nezidingo zakho zocwaningo.
Imigomo Yokukhokha?I-invoyisi ye-Proforma izothunyelwa kuqala ngemva kokuqinisekiswa kwe-oda, kufakwe nemininingwane yethu yasebhange.Inkokhelo nge-T/T (Telex Transfer), PayPal, Western Union, njll.
Izimpawu Zengozi Xi - Iyacasula
Amakhodi Engozi R36 - Ukucasula emehlweni
R36/37/38 - Ukucasula amehlo, uhlelo lokuphefumula kanye nesikhumba.
Incazelo Yezokuphepha S26 - Uma uthintana namehlo, geza ngokushesha ngamanzi amaningi futhi ufune iseluleko sezokwelapha.
I-S36 - Gqoka izingubo ezifanele zokuzivikela.
I-WGK Germany 3
I-RTECS GU2292000
TSCA Yebo
I-HS Code 3505100000
I-α-Cyclodextrin (α-CD) (CAS: 10016-20-3)iyi-saccharide enganciphisi ehlanganisa amayunithi eglucose ayisithupha axhunywe amabhondi e-alpha-1.4.Ikhiqizwa isenzo se-cyclodextrin glucosyl transferase kumasyrups e-starch e-hydrolysed.I-cavity ye-alpha-Cyclodextrin ingaphansi kwe-beta-Cyclodextrin, ngakho-ke isetshenziselwa ukuvumela ukwakheka kwama-inclusion complexes anama-molecule amancane.Idigri ye-solubility ye-Alpha-Cyclodextrin emanzini ngu-14.5 g/100ml @25°C, ngakho-ke isimo esidinga ukunyibilika okuphezulu kwe-cyclodextrin.
I-Alpha-cyclodextrin isetshenziswa kabanzi emithini, ukudla, ukunambitheka nezimonyo.I-Alpha-cyclodextrin iphinde isetshenziswe kabanzi emkhakheni wokubulala izinambuzane kanye nokulungisa i-metabolization yezitshalo nokwandisa inani lesitshalo.Ikakhulukazi i-cyclodextrin kanye ne-ramification yayo eyathuthukiswa yile minyaka, ezinye zazo ziyi-solutizer ebalulekile, i-stablizer, isikhiphi noma izinto ezisizayo zezidakamizwa ze-Entericoated, ezinye zazo ziyizinto zezinto eziphilayo zokwenziwa ze-macromolecular.
Ibanga lokudla i-Alpha cyclodextrin enamayunithi angu-6 eglucose inesikhala esincane kakhulu se-cyclodextrins engumzali.Iwusizo ekuncibilikiseni, ekuqiniseni noma ekuletheni amangqamuzana amancane, isb. Isisindo esiphansi samangqamuzana, ukunambitheka noma iphunga elimnandi. Ibanga lokudla I-Alpha cyclodextrin yethulwa embonini yokudla njengefayibha yokudla encibilikayo enezici ezikholisayo.
I-Cyclodextrin inembobo enkabeni yesakhiwo sendandatho, kanye ne-athomu yomoya-mpilo lapho -CH- ibophezela ku-glucoside.Ine-sulphur-aqueous, futhi amaqembu e-hydroxyl asendaweni engu-2, 3 kanye ne-6 ye-glucose ayi-hydrophilic.Ingasetshenziselwa ukuhlanganisa amanye ama-molecule abe yizinhlanganisela ezifakiwe ngamandla abuthakathaka e-van der Waals.Izinto eziningi zingagqunywa ngama-cyclodextrins, okuhlanganisa amagesi ahloniphekile, ama-halogen, odayi, amakha, imithi, ukudla, izibulala-zinambuzane nezivimbelakuvunda.Ngemuva kwe-encapsulation, ukuzinza kwayo, ukuguquguquka, ukuncibilika kanye nokusebenza kabusha kuyathuthukiswa.Umphumela okhethekile we-Cyclodextrin wenza kube yinto esetshenziswa kabanzi ye-encapsulation.
1. Ukusetshenziswa kwe-Cyclodextrin embonini yezemithi kungenza i-encapsulation (encapsulation) nezidakamizwa, ezingenza (1) Izidakamizwa ezingazinzile zizinze;(2) I-Deliquescence, adhesion noma i-liquid drug powderization;(3) Izidakamizwa ezingancibiliki noma ezingancibiliki zingancibilika (zincibilikisiwe), njll.
2. Ukusetshenziswa embonini yezibulala-zinambuzane i-cyclodextrin encapsulation stabilization, ezinye izibulala-zinambuzane zingagcinwa futhi zithuthukise ukusebenza kahle kwezinambuzane.
3. Ukusetshenziswa embonini yokudla i-cyclodextrin isetshenziswa embonini yokudla, inemiphumela elandelayo: (1) Ukuqedwa nokuvala iphunga elikhethekile;(2) Ukuthuthukiswa kanye nokuthuthukiswa kwesakhiwo sezicubu zokudla;(3) ukudambisa nokususwa kokunambitha okubabayo;(4) Umphumela we-Antioxidant;(5) Ukulondoloza kanye nokwenza kahle ukunambitheka.
4. Ukusetshenziswa kwe-Cyclodextrin embonini yamakhemikhali yansuku zonke ekukhiqizeni izimonyo kungasetshenziswa futhi njenge-emulsifier kanye nesithuthukisi sekhwalithi.Iphinde ibe ne-deodorization (njengokwengeza i-halitosis) kanye nemiphumela ye-antiseptic, ingasetshenziselwa umuthi wokuxubha, ukukhiqiza impushana yezinyo.
5. Okunye ukusetshenziswa ekuvikelweni kwemvelo kungasetshenziswa njenge-ejenti yokwelapha indle enamafutha.Isixazululo esinamanzi se-Cyclodextrin sisetshenziselwa ukuhlanza ithangi likawoyela, futhi uketshezi olubi lungatholwa futhi luphathwe ukuze kutholwe uwoyela wokubasa.
6. Ukusetshenziswa kwe-cyclodextrin ku-chemistry Cyclodextrin iyi-reagent yamakhemikhali ebalulekile.Uma ikhona, amandla e-fluorescence e-fluorochrome azokhula kakhulu, ngakho-ke ingasetshenziselwa ukuhlaziya amaprotheni nama-amino acid.Ingasetshenziswa futhi ukuhlukanisa ama-organic chain compounds, ama-racemes, njll.
Ngaphezu kwalokho, i-adsorbent eyenziwe nge-Cyclodextrin ingasetshenziselwa i-chromatographic adsorption.
Umsebenzi
1. I-α-Cyclodextrin Khulisa ukuzinza kwezinto: Vimbela ukuguquguquka, vimbela ukufakwa kwe-sublimation;I-Anti-oxidation;Vimbela ukubola kwe-optothermal;Ukubola kwamakhemikhali okulwa;Nweba isikhathi sokufaneleka kwento.
2. I-α-Cyclodextrin Khulisa ukuncibilika kwezinto ezibonakalayo kanye nokutholakala kwe-bioavailability.
3. I-α-Cyclodextrin ngokwakhiwa kwenkimbinkimbi yokuhlanganisa ukuze kuzuzwe ikhava ephunga elimnandi.
4. Umuthi we-α-Cyclodextrin Liquid ube esimweni esiqinile.
5. I-α-Cyclodextrin Ukuvimbela izidakamizwa - izidakamizwa, izidakamizwa - ukusebenzisana phakathi kwesithasiselo.
6. I-α-Cyclodextrin Yehlisa imiphumela emibi.
Isicelo
I-1. I-α-Cyclodextrin isetshenziselwa ukukhulisa ukuzinza kwezinto:Vimbela ukuguquguquka, ukuvimbela i-sublimation;I-Anti-oxidation;
2. I-α-Cyclodextrin isetshenziselwa ukuvimbela ukubola kwe-optothermal;Ukubola kwamakhemikhali okulwa;Nweba isikhathi sokufaneleka kwento.
3. I-α-Cyclodextrin isetshenziselwa ukwandisa ukuncibilika kwezinto ezibonakalayo kanye nokutholakala kwe-bioavailability.
4. Ngokwakhiwa kwe-inclusion complex ukuze kutholakale ikhava ephumelelayo iphunga elimnandi.Isidakamizwa esiwuketshezi sibe sesimeni esiqinile.
5. I-α-Cyclodextrin isetshenziselwa ukuvimbela izidakamizwa - izidakamizwa, izidakamizwa - ukusebenzisana phakathi kokuhlanganisa.
6. I-α-Cyclodextrin isetshenziselwa ukunciphisa imiphumela emibi.
Ezemithi:
1. Ukwandisa ukuncibilika kokutholakala kwezinto eziphilayo
2. Ukwenza ngcono i-bioavailability
3. Ukulungisa noma ukulawula ukukhishwa
4. Ukunciphisa ubuthi
5. Ukwenza ngcono ukuzinza
Izimonyo:
1. Ukuze ivumelane encapsulation of ezishintshashintshayo compounds.
2. Ukwandisa impilo yeshalofu yezinambitheka ezibizayo.
Ukudla:
1.Ukuvimbela ukuhwamuka kwezinto eziguquguqukayo.
2.Ukuqeda iphunga elibi.
3.Ukuthuthukisa kakhulu imiphumela ye-emulsification
I-α-Cyclodextrin itholakala ukwenza inkimbinkimbi eqinile ngamafutha okudla.Ngale ndlela kunciphisa i-bioavailability kanye nokumuncwa kwamafutha.Kuyaziwa ukuthi ilawula amazinga e-triglyceride ne-leptin ku-serum.Kumamodeli wamagundane, i-α-Cyclodextrin iboniswa ukuthi ibangele ukuzwela kwe-insulin kanye nokuphuma kwamafutha e-fecal.Ngakho-ke, i-α-Cyclodextrin ibhekwa njengesebenzayo ekwelapheni ukukhuluphala kanye ne-metabolic syndromes.
Kufakwe ku-FDA Inactive Ingredients Database: α-Cyclodextrin (amalungiselelo omjovo);β-Cyclodextrin (amaphilisi omlomo, ama-topical gels);γ-Cyclodextrin (IV imijovo).Kufakwe ohlwini lwe-Canada Lwezithako Ezingezona Ezokwelapha Ezamukelekayo (i-ejenti yokuzinzisa; i-ejenti e-solubilizing);kanye nasemikhiqizweni yemithi yomlomo nengamarectal enelayisensi e-Europe, Japan, nase-USA.