I-Hydroxypropyl-β-Cyclodextrin CAS 128446-35-5 (HP-β-CD) I-Pharmaceutical Excipients Isithombe Esifakiwe

I-Hydroxypropyl-β-Cyclodextrin CAS 128446-35-5 (HP-β-CD) Ama-Excipients Emithi

Incazelo emfushane:

Igama Lekhemikhali: Hydroxypropyl-β-Cyclodextrin

Synonym: Cyclodextrin HPB;I-HPBCD;I-HP-β-CD

I-CAS: 128446-35-5

Impushana emhlophe noma ecishe ibe mhlophe noma eyiCrystalline Powder

Thintana: UDkt. Alvin Huang

Iselula/Wechat/WhatsApp: +86-15026746401

E-Mail: alvin@ruifuchem.com

Thumela i-imeyili kithi

Imininingwane Yomkhiqizo

Imikhiqizo Ehlobene

Omaka bomkhiqizo

Incazelo:

I-Ruifu Chemical ingumkhiqizi ohamba phambili we-Hydroxypropyl-β-Cyclodextrin (HPBCD; HP-β-CD) (CAS: 128446-35-5) enekhwalithi ephezulu.I-Ruifu Chemical inganikeza ukulethwa komhlaba wonke, intengo encintisanayo, isevisi enhle kakhulu, amanani amancane kanye nenqwaba etholakalayo.Thenga i-Hydroxypropyl-β-Cyclodextrin,Please contact: alvin@ruifuchem.com

Chemical Properties:

Igama Lekhemikhali	IHydroxypropyl-β-Cyclodextrin
Omqondofana	Cyclodextrin HPB;I-Hydroxypropyl-Beta-Cyclodextrin;(2-Hydroxypropyl)-β-Cyclodextrin;(2-Hydroxypropyl)-beta-Cyclodextrin;i-beta-Hydroxypropylcyclodextrin;HBC;I-HPBCD;I-HP-β-CD
Isimo Sesitoko	Ku-Stock, Commercial Production
Inombolo ye-CAS	128446-35-5
I-Molecular Formula	I-C63H112O42
Isisindo samangqamuzana	1541.54 g/mol
I-Melting Point	262.0~269.0℃
Ukuminyana	1.05
Ukuzungezisa Okuthile [a]20/D	+120° ukuya +135° (C=1, H2O)
Ukuncibilika kwamanzi	Incibilika Emanzini
I-COA ne-MSDS	Iyatholakala
Isampula yamahhala	Iyatholakala
Umsuka	Shanghai, China
Ibhrendi	I-Ruifu Chemical

Imininingwane:

Izinto	Imininingwane	Imiphumela
Ukubukeka	Impushana Emhlophe, Engenacala, Emsulwa	Kuyavumelana
I-IR Spectrum	Amabhendi Okumuncwa afanayo ane-USP Hydroxypropyl Betadex RS	Kuyavumelana
pH	5.0~7.5	6.57
Ukucaca Kwesixazululo	Isixazululo Esicacile Nesingenambala	Kuyavumelana
Ukulahlekelwa Ekumisweni	≤10.0%	3.5%
Izinsalela ekushiseni	≤0.20%	0.09%
Izinsimbi Ezisindayo	≤20ppm	<10ppm
I-Chloride	≤0.05%	<0.05%
Ukushintshwa kwe-Molar	0.4~1.5	0.63
I-Conductivity	10% (w/v) Isixazululo samanzi ≤200μS/cm	154µS/cm
Izinga Lokushintsha	2.8~10.5	5.3
I-Betadex esele	≤1.50%	0.12%
Ipropylene Glycol	≤2.50%	0.29%
I-Propylene oxide	≤1ppm	<1ppm
Noma Ikuphi Okunye Ukungcola Okukodwa	≤0.25%	<0.25%
Isamba Sokunye Ukungcola	≤1.00% (Ngaphandle kwe-Betadex ne-Propylen Glycol)	0.51%
I-TAMC	≤1000cfu/g	30cfu/g
I-TYMC	≤100cfu/g	10cfu/g
Escherichia Coli	Ayitholakali	Kuyavumelana
I-Salmonella	Akekho	Akekho
Ama-bacterium Endotoxins	<10IU/g	<10IU/g
Isiphetho	Ihloliwe futhi Ihambisana Nezinga le-USP35

Iphakheji/Isitoreji/Ukuthumela ngomkhumbi:

Iphakheji:Ibhodlela eliFluorinated, isikhwama se-Aluminium foil, 25kg/Cardboard Drum, noma ngokwezidingo zekhasimende.
Isimo Sesitoreji:Gcina isitsha sivalwe ngokuqinile futhi usigcine endaweni epholile, eyomile futhi enomoya omuhle kude nezinto ezingahambelani.Vikela ekukhanyeni nakumswakama.Akuhambisani nama-oxidizing agents aqinile.
Ukuthumela:Zilethe emhlabeni wonke ngendiza, yi-FedEx/DHL Express.Nikeza ukulethwa okusheshayo nokuthembekile.

Izinzuzo:

Amandla Anele: Izinsiza ezanele kanye nochwepheshe

Isevisi Yobuchwepheshe: Isevisi yokuthenga yokuma eyodwa

Iphakheji le-OEM: Iphakheji yangokwezifiso kanye nelebula iyatholakala

Ukulethwa Okusheshayo: Uma kungaphakathi kwesitoko, ukulethwa kwezinsuku ezintathu kuqinisekisiwe

Impahla Ezinzile: Gcina isitoko esinengqondo

Ukusekelwa Kwezobuchwepheshe: Isixazululo sezobuchwepheshe siyatholakala

Isevisi Yokuhlanganisa Ngokwezifiso: Isukela kumagremu kuye kumakhilo

Ikhwalithi Ephezulu: Kusungulwe uhlelo oluphelele lokuqinisekisa ikhwalithi

I-FAQ:

Indlela Yokuthenga?Sicela uxhumaneDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com

Iminyaka engu-15 Yokuhlangenwe nakho?Sinesipiliyoni seminyaka engaphezu kwe-15 ekwakhiweni nasekuthumeleni kwamanye amazwe uhla olubanzi lwezinga eliphezulu lokuxhumanisa imithi noma amakhemikhali amahle.

Izimakethe Eziyinhloko?Thengisa emakethe yasekhaya, eNyakatho Melika, eYurophu, eNdiya, eKorea, eJapane, e-Australia, njll.

Izinzuzo?Ikhwalithi ephezulu, intengo ethengekayo, izinsizakalo ezichwepheshile nokusekelwa kobuchwepheshe, ukulethwa okusheshayo.

IkhwalithiIsiqiniseko?Isistimu yokulawula ikhwalithi eqinile.Imishini yobuchwepheshe yokuhlaziya ifaka i-NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, NOMA, KF, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, njll.

Amasampula?Imikhiqizo eminingi inikeza amasampula wamahhala wokuhlolwa kwekhwalithi, izindleko zokuthumela kufanele zikhokhelwe amakhasimende.

Ukuhlolwa Kwemboni?Wamukelekile ekucwaningweni kwemboni.Sicela wenze i-aphoyintimenti kusengaphambili.

I-MOQ?Ayikho i-MOQ.I-oda elincane liyamukeleka.

Isikhathi sokuthumela? Uma kungaphakathi kwesitoko, ukulethwa kwezinsuku ezintathu kuqinisekisiwe.

Ezokuthutha?By Express (FedEx, DHL), by Air, by Sea.

Amadokhumenti?Ngemuva kwenkonzo yokuthengisa: I-COA, i-MOA, i-ROS, i-MSDS, njll.

Custom Synthesis?Ingahlinzeka ngezinsizakalo zokwenziwa ngokwezifiso ukuze zilingane kangcono nezidingo zakho zocwaningo.

Imigomo Yokukhokha?I-invoyisi ye-Proforma izothunyelwa kuqala ngemva kokuqinisekiswa kwe-oda, kufakwe nemininingwane yethu yasebhange.Inkokhelo nge-T/T (Telex Transfer), PayPal, Western Union, njll.

128446-35-5 - Ubungozi nokuphepha:

Incazelo Yokuphepha	24/25 - Gwema ukuthintana nesikhumba namehlo.
I-WGK Germany	3
I-RTECS	GU2293332
Ikhodi ye-HS	3505100000

128446-35-5 - Ukusetshenziswa:

I-Hydroxypropyl-β-Cyclodextrin (HPBCD; HP-β-CD) (i-CAS: 128446-35-5) i-cyclodextrin eguquliwe esetshenziswa kabanzi, i-lipophilic cavity eyakhiwe ngamayunithi e-glucose angu-7.Ukunyibilika kwezidakamizwa emanzini kuthuthukiswa kakhulu ngokuhlanganisa ne-HP-β-CD.I-Enteric coating, ukwakheka kokukhululwa okuqhubekayo, ukulethwa kwezidakamizwa ze-buccal kanye ne-transdermal.
I-Hydroxypropyl-β-Cyclodextrin, okuphuma ku-hydroxyalkyl, ithola isicelo njengemoto yokubunjwa esetshenziselwa ukuthuthukisa ukunyibilika kwezidakamizwa ezixazululweni ezinamanzi ukuze kuthunyelwe ngempumelelo ama-ejenti wezokwelapha ezinhlelweni zebhayoloji.Ngokuvamile isetshenziswa esikhundleni se-α-, β- kanye ne-γ-Cyclodextrins.

128446-35-5 - Izicelo Zemithi:

IHydroxypropyl betadex iye yaphenywa kabanzi kwezokwelapha futhi iye yasetshenziswa ngokuyinhloko njenge-solubilizer yama-molecule e-hydrophobic oketshezini lomlomo, okuqinile orals, parenterals, ama-inhaler anemithamo ecindezelweyo, iziphefumula zempushana ezomile, kanye nokwakheka kwezihloko.Kuphinde kwaboniswa ukuthi kusebenza njengesizinzi ngesikhathi sokucubungula nokugcinwa kokwakheka.I-Hydroxypropyl betadex inclusion complexes kubikwe ukuthi ikhombisa izakhiwo zemishini ezihlukile ezintweni ezihlanzekile.Inzuzo ebikiwe ye-hydroxypropyl betadex ngaphezu kwe-b-cyclodextrin engashintshwanga ukuncibilika kwayo okukhulu kwamanzi.

128446-35-5 - Umsebenzi:

1. I-Solubilization kanye ne-solubilization, yenza izidakamizwa ezingancibiliki zincibilike, zithuthukise ukunyibilika kwezingxenye ezisebenzayo zezidakamizwa ezinamafutha, ziqondise ukulethwa kwezidakamizwa futhi zivikele ukusebenza kahle kwezithako zezidakamizwa.
2. Thuthukisa i-bioavailability yomuthi, wandise umphumela wokwelapha womuthi noma wehlise umthamo.
3. Lungisa noma ulawule izinga lokukhululwa kwezidakamizwa ukuze unciphise imiphumela emibi.
4. Gcoba iphunga elibi.

128446-35-5 -Isicelo:

1) Emkhakheni wemithi,
1. I-Hydroxypropyl Beta Cyclodextrin ingakhuphula ukunyibilika komuthi nokutholakala kwezinto eziphilayo, iphinde yengeze umphumela omuhle futhi yehlise umthamo.
2. I-HP-β-CD ingalawula noma ilungise isivinini sokusebenza, yehlise ubuthi bomuthi futhi ithuthukise ukuzinza kwezidakamizwa.
3. I-solubilizer yomjovo efanelekile kanye nezinto ezisiza izidakamizwa ngenxa yomsebenzi ophansi ongaphezulu nomsebenzi we-hemolytic, akukho ukucasuka kwemisipha.
4. I-HP-β-CD ayisetshenziselwa kuphela izidakamizwa zomlomo, umjovo, uhlelo lokulethwa kwezidakamizwa ze-mucosal, uhlelo lokulethwa kwezidakamizwa ze-transdermal, i-lipotropy eqondiswe ophethe izidakamizwa, kodwa futhi ingasetshenziswa njenge-protein protective agent kanye ne-stabilizer.
5. Ukuthuthukisa izakhiwo ze-organoleptic zezinto ezibabayo noma ezingemnandi.
2) Emkhakheni wokudla,
1. I-HP-β-CD ingavimbela ukuhwamuka kwezinto eziguquguqukayo kugcina ukuqina kwemisoco yayo, isuse iphunga elibi futhi ingathuthukisa kakhulu imiphumela ye-emulsification ngokusetshenziswa okuhlangene kwama-emulsifiers okudla.
2. I-HP-β-CD ingenza futhi isivikelo sokuphuma kokudla kancane kancane, inyuse umphumela wokunqanda ukugqwala futhi yandise impilo yeshalofu yokudla.
3) Embonini Yezimonyo
1. Kwezimonyo izinto zokusetshenziswa ezisetshenziswa njenge-stabilizer, emulsifier, solubilizer njll.
2. I-HP-β-CD inganciphisa ukugqugquzelwa esikhumbeni, futhi ithuthukise ukuqina kwezingxenye ezisebenzayo
3. I-HP-β-CD inganciphisa noma imaski iphunga elibi le-nutrition molecular.
4. Vimbela ukwakheka kwezakhi zokuguquguquka, i-oxidation, khulisa ukungakwazi ukusebenza, i-essence, i-perfume encibilikayo emanzini futhi Gcina iphunga liphuma kancane futhi lihlala njalo.