I-D-Histidine CAS 351-50-8 HD-His-OH Assay 98.5~101.0% Factory
I-Shanghai Ruifu Chemical Co., Ltd. ingumkhiqizi ohamba phambili we-D-Histidine (HD-His-OH) (CAS: 351-50-8) enekhwalithi ephezulu.I-Ruifu Chemical ihlinzeka ngochungechunge lwama-amino acid nokuphuma kokunye.Singahlinzeka ngezidingo zomhlaba wonke, amanani ancintisanayo, amanani amancane kanye nenqwaba etholakalayo.Thenga i-D-Histidine,Please contact: alvin@ruifuchem.com
Igama Lekhemikhali | I-D-Histidine |
Omqondofana | I-HD-His-OH;D-His-OH;I-Dextro-Histidine;(R)-Histidine;(R)-2-Amino-3-(4-Imidazolyl)i-propionic Acid |
Isimo Sesitoko | Esitokweni, Amandla Okukhiqiza Amathani angama-30 ngenyanga |
Inombolo ye-CAS | 351-50-8 |
I-Molecular Formula | I-C6H9N3O2 |
Isisindo samangqamuzana | 155.16 g/mol |
I-Melting Point | 280.0~288.0℃ |
Ukuminyana | 1.423 |
Ukuncibilika kwamanzi | Incibilika Emanzini, 42 g/L (25℃) |
Ukuncibilika | 1 M HCl: I-Soluble (50 mg/ml) |
Isikhathi Sokugcina. | Indawo epholile neyomile (2~8℃) |
I-COA ne-MSDS | Iyatholakala |
Isigaba | Ama-Amino Acids kanye Neziqephu |
Ibhrendi | I-Ruifu Chemical |
Izinto | Amazinga Wokuhlola | Imiphumela |
Ukubukeka | I-Crystalline Powder Emhlophe | Iyahambisana |
Ukuhlonza | Ihlangabezana Nemfuneko | Iyahambisana |
Ukuzungezisa Okuthile [α]20/D | +36.5° ukuya +40.5° (C=2, H2O) | +38.2° |
I-Chloride (Cl) | ≤0.020% | <0.020% |
I-Sulfate (SO4) | ≤0.020% | <0.020% |
I-Ammonium (NH4) | ≤0.020% | <0.020% |
Izinsimbi Ezisindayo (Pb) | ≤10ppm | <10ppm |
Insimbi (Fe) | ≤10ppm | <10ppm |
I-Arsenic (As2O3) | ≤1ppm | <1ppm |
Ukulahlekelwa Ekumisweni | ≤0.20% | 0.15% |
Izinsalela ekushiseni | ≤0.10% | 0.06% |
Amanye ama-Amino Acids | ≤0.50% | <0.50% |
Isivivinyo | 98.5%~101.0% | 99.54% |
pH | 7.0~8.5 | 7.6 |
Isiphetho | Umkhiqizo uhloliwe futhi uthobelana nezicaciso |
Iphakheji: Ibhodlela eliFluorinated, isikhwama se-Aluminium foil, 25kg/Cardboard Drum, noma ngokwezidingo zekhasimende.
Isimo Sesitoreji:Gcina ezitsheni ezivaliwe endaweni epholile neyomile (2~8℃) kude nezinto ezingahambelani.Vikela ekukhanyeni nakumswakama.
pH
thatha u-1.0g walo mkhiqizo, ungeze u-50ml wamanzi ukuze uwancibilikise, futhi uwalinganise ngokomthetho (Umthetho ojwayelekile 0631).Inani le-pH kufanele libe ngu-7.0~8.5.
Ukudluliswa Kwesixazululo
Thatha u-0.60g walo mkhiqizo, engeza amanzi angu-20ml ukuze uncibilike, ngokusho kwe-UV-visible spectrophotometry (Umthetho ojwayelekile 0401), ulinganise ukudluliselwa ku-430nm wavelength, hhayi ngaphansi kuka-98.0%.
I-Chloride
Thatha u-0.25g walo mkhiqizo futhi uwuhlole ngokomthetho (Umthetho ojwayelekile 0801).Uma kuqhathaniswa nesisombululo sokulawula esenziwe nge-0.02% yesisombululo esijwayelekile se-sodium chloride, akufanele sigxile kakhulu ().
I-sulfate
Thatha u-1.0g walo mkhiqizo futhi uwuhlole ngokomthetho (Umthetho ojwayelekile 0802).Uma kuqhathaniswa nesisombululo sokulawula esenziwe nge-0.02% yesisombululo esijwayelekile se-potassium sulfate, akufanele sigxile kakhulu ().
Usawoti we-ammonium
thatha u-0.10g walo mkhiqizo futhi uwuhlole ngokomthetho (Umthetho ojwayelekile 0808).Uma kuqhathaniswa nesixazululo sokulawula esenziwe ngo-0.02% wesisombululo esijwayelekile se-ammonium chloride, akufanele sijule ().
Amanye ama-Amino Acids
thatha inani elifanele lalo mkhiqizo, engeza amanzi azowancibilikisa futhi ahlanjululwe ukwenza isixazululo esiqukethe cishe u-10 mg nge-lml ngayinye njengesixazululo sokuhlola;Thatha i-1ml yesilinganiso esinembile bese uyibeka ku-flask yokulinganisa engu-200ml, hlanza ukuze ulinganise ngamanzi, unyakazise kahle, njengesixazululo sokulawula;Thatha inani elifanele lereferensi ye-histidine kanye nereferensi ye-proline ngokulandelanayo, bese ubeka kuflask yokulinganisa efanayo, amanzi ayengezwa ukuze ahlakazeke futhi ahlanjululwe ukuze kulungiswe isixazululo esiqukethe cishe i-0.4mg ngayinye nge-1ml njengesisombululo esifanele uhlelo.Ngokokuhlolwa kongqimba oluncane lwe-chromatography (Okujwayelekile 0502), Dweba u-5 u1 wesixazululo ngasinye kwezithathu ezingenhla, ngokulandelana ukhombe kupuleti longqimba olufanayo lwe-silica G, elinesisombululo se-ammonia esigxilwe yi-N-propanol (67:33) njenge ukukhiqiza isincibilikisi, khulisa, somile, fafaza nge-ninhydrin kusisombululo se-acetone (1-50), shisa ku-80°C kuze kuvele amachashaza, bese uhlola ngokushesha.Isixazululo sokulawula kufanele sibonise indawo ecacile, futhi isisombululo esisebenzayo sesistimu kufanele sibonise izindawo ezimbili ezihlukene ngokuphelele.Uma isisombululo sokuhlola sibonisa izindawo zokungcola, umbala akufanele ujule (0.5%) kunendawo eyinhloko yesisombululo sokulawula.
Ukulahlekelwa Ekumisweni
thatha lo mkhiqizo, wome ku-105℃ amahora angu-3, ukulahlekelwa isisindo akufanele kudlule u-0.2% (Umthetho ojwayelekile 0831).
Izinsalela ekushiseni
Angabi ngaphezu kuka-0.1% (Umthetho ojwayelekile 0841).
Usawoti Wensimbi
thatha u-1.0g walo mkhiqizo futhi uwuhlole ngokomthetho (Umthetho ojwayelekile 0807).Uma kuqhathaniswa nesixazululo sokulawula esenziwe nge-0.001% yesisombululo sensimbi esijwayelekile, ngeke sijule ().
Izinsimbi ezinzima
Lo mkhiqizo 1.0g, ukuhlolwa ngokomthetho (General Principles 0821 Umthetho wokuqala), oqukethe izinsimbi ezisindayo ngeke kweqe izingxenye 10 esigidini ngasinye.
I-Arsenic Usawoti
thatha u-2.0g walo mkhiqizo, engeza u-23ml wamanzi ukuze uhlakaze, engeza u-5ml we-hydrochloric acid, hlola ngokomthetho (Umthetho ojwayelekile 0822 umthetho wokuqala), kufanele uhambisane nezinhlinzeko (0.0001%).
I-Endotoxin yebhaktheriya
Thatha lo mkhiqizo, hlola ngokomthetho (Umthetho ojwayelekile 1143), i-lg histidine ngayinye equkethe i-endotoxin kufanele ibe ngaphansi kuka-6.0EU.(Okomjovo)
351-50-8 - Ukuzimisela okuqukethwe
Thatha lo mkhiqizo cishe u-0.15g, isisindo esinembile, engeza i-anhydrous formic acid engu-2ml ukuze incibilike, engeza i-glacial acetic acid engu-50ml, ngokuya ngendlela engase ibe khona ye-titration (Umthetho ojwayelekile 0701), ne-perchloric acid titration solution (0.1 mol/L) titration, kanye imiphumela ye-titration yalungiswa ngokuhlolwa okungenalutho.Isixazululo ngasinye esingu-1 ml se-perchloric acid titration (0.1 mol/L) sihambisana no-15.52mg we-C6H9N302.
Indlela Yokuthenga?Sicela uxhumaneDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
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IkhwalithiIsiqiniseko?Isistimu yokulawula ikhwalithi eqinile.Imishini yobuchwepheshe yokuhlaziya ifaka i-NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, NOMA, KF, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, njll.
Amasampula?Imikhiqizo eminingi inikeza amasampula wamahhala wokuhlolwa kwekhwalithi, izindleko zokuthumela kufanele zikhokhelwe amakhasimende.
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I-S36/37 - Gqoka izingubo zokuzivikela ezifanele namagilavu.
S26 - Uma uthintana namehlo, geza ngokushesha ngamanzi amaningi futhi ufune iseluleko sezokwelapha.
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I-HS Code 2922491990
I-D-Histidine (HD-His-OH) (CAS: 351-50-8) i-isomer engeyona eyemvelo, engasebenzi ngokwebhayoloji ye-L-Histidine.I-D-Histidine yaziwa ngokuvimbela ukuhlukana kwamaseli, futhi isetshenziswa nezinhlobo ezithile zamagciwane (njenge-Escherichia coli) njengomthombo we-L-Histidine.Ifomu elisebenzayo le-histidine eline-D-configuration.
Ama-amino acid kanye nokuphuma kokunye, asetshenziswa ku-peptide synthesis, asetshenziswa njenge-organic synthesis intermediate, pharmaceutical intermediate, angasetshenziswa njenge-chiral intermediate, i-biochemical reagent noma i-chemical reagent.
I-D-Histidine ingasetshenziswa ekwakhiweni kwezidakamizwa ze-peptide, ama-peptide e-cationic, njengama-analogues e-carnosine.I-D-Histidine ingase futhi isetshenziswe njenge-ejenti yokuthunjwa kwensimbi esindayo.