I-Darifenacin Hydrobromide Darifenacin HBr CAS 133099-07-7 Assay ≥99.0% API Factory High Quality
Ukunikezela Komkhiqizi Ngokuhlanzeka Okuphezulu kanye Nekhwalithi Ezinzile
Igama Lekhemikhali: I-Darifenacin Hydrobromide
I-CAS: 133099-07-7
I-Darifenacin hydrobromide iyimbangi ekhethiwe ye-M3 muscarinic receptor esetshenziselwa ukwelapha ukungakwazi ukuzithiba komchamo kanye nesifo sesinye esisebenza ngokweqile.
Ikhwalithi ephezulu ye-API, Ukukhiqiza Kwezentengiso
Igama Lekhemikhali | I-Darifenacin Hydrobromide |
Omqondofana | I-Darifenacin HBr;UK-88525;Nika amandlax |
Inombolo ye-CAS | 133099-07-7 |
Inombolo yeCAT | I-RF-API94 |
Isimo Sesitoko | Esitokweni, Isikali Sokukhiqiza Sifika Emakhulwini Amakhilogremu |
I-Molecular Formula | I-C28H30N2O2.HBr |
Isisindo samangqamuzana | 507.46 |
I-Melting Point | 228.0~230.0℃ |
Ukuncibilika | I-DMSO: I-Soluble 20mg/ml, Icacile |
Izinga Lokushisa Lesitoreji | Gcina Isikhathi Eside ku -20 ℃ |
Ibhrendi | I-Ruifu Chemical |
Into | Imininingwane |
Ukubukeka | I-Crystalline Powder Emhlophe |
Ukuncibilika | Incibilika Kancane ku-Methanol, Incibilika Kancane Emanzini Futhi Ayincibiliki ku-Chloroform |
Ukuhlonza IR | I-Spectrum yesampula ihambisana naleyo yezinga lereferensi |
Ukuhlonza HPLC | Isikhathi sokugcina sesiqongo esikhulu sesixazululo sesampula sihambisana naleso sesixazululo esijwayelekile |
Izinto Ezihlobene | |
Ubukhulu.Ukungcola Okukodwa | ≤0.50% |
Ukungcola Okuphelele | ≤1.0% |
Isomer ye-Optical | ≤0.50% |
Izincibilikisi Ezisele | |
I-Ethyl Acetate | ≤0.50% |
I-Ethanol | ≤0.50% |
I-Methanol | ≤0.30% |
I-acetone | ≤0.50% |
1-Butanol | ≤0.50% |
Ukulahlekelwa Ekumisweni | ≤1.0% (Yoma ku-105℃ kumshini wokomisa womoya kagesi kuze kube nesisindo esingashintshi) |
Izinsalela ekushiseni | ≤0.10% |
Izinsimbi Ezisindayo | ≤20ppm |
Isivivinyo | ≥99.0% (komisiwe) |
I-Shelf Life | Izinyanga ezingama-24 |
Izinga Lokuhlola | I-Enterprise Standard |
Ukusetshenziswa | I-API, Isinye Esisebenza Kakhulu |
Iphakheji: Ibhodlela, isikhwama se-Aluminium foil, isigubhu seCardboard, 25kg/Drum, noma ngokwezidingo zekhasimende.
Isimo Sesitoreji:Gcina ezitsheni ezivaliwe endaweni epholile neyomile;Vikela ekukhanyeni, umswakama kanye nezinambuzane.
I-Darifenacin Hydrobromide, i-Darifenacin HBr (i-CAS 133099-07-7), esebenza ngomlomo, i-M3 receptor antagonist ekhethiwe kanye ngosuku, yethulwa ukuze zelashwe esinyeni esisebenza ngokweqile ezigulini ezinezimpawu zokuthi ukungakwazi ukuzibamba komchamo, ukuphuthuma kanye nemvamisa.Umuthi uvimbela ngokukhethekile i-M3 receptor ku-muscle detrusor ngenkathi usindisa i-M1 ne-M2 receptors okukholelwa ukuthi ihileleke ohlelweni lwezinzwa oluphakathi nokusebenza kwenhliziyo ngokulandelana.Ikhompiyutha ekuqaleni yasungulwa ngabakwaPfizer futhi yanikezwa ilayisense kwaNovartis naseBayer.