I-DCC CAS 538-75-0 Dicyclohexylcarbodiimide Purity >99.0% (GC) I-Peptide Coupling Reagent Factory
I-Shanghai Ruifu Chemical Co., Ltd. ingumkhiqizi ohamba phambili we-N,N'-Dicyclohexylcarbodiimide (DCC) (CAS: 538-75-0) enekhwalithi ephezulu.I-Ruifu Chemical ihlinzeka ngochungechunge lwama-reagents avikelayo kanye nama-reagents ahlanganisayo.I-Ruifu inganikeza ukulethwa komhlaba wonke, intengo encintisanayo, amanani amancane nayinqwaba atholakalayo.Thenga i-DCC,Please contact: alvin@ruifuchem.com
Igama Lekhemikhali | N,N'-Dicyclohexylcarbodiimide |
Omqondofana | I-DCC;I-Dicyclohexylcarbodiimide |
Inombolo ye-CAS | 538-75-0 |
Isimo Sesitoko | Esitokweni, Isikali Sokukhiqiza Sifinyelela Kumathani |
I-Molecular Formula | I-C13H22N2 |
Isisindo samangqamuzana | 206.33 |
I-Melting Point | 32.0 ~ 36.0℃ |
Iphuzu elibilayo | 122.0~124.0℃/6 mm Hg(lit.) |
Ukuminyana | 1.247 g/mL ku-25℃ |
Kuyazwela | Kuyazwela Umswakama |
Ukuncibilika Emanzini | Ayincibiliki Emanzini |
Ukuncibilika | I-Soluble ku-Methanol |
Isikhathi Sokugcina. | Indawo epholile neyomile (2~8℃) |
I-COA ne-MSDS | Iyatholakala |
Isigaba | Ama-Reagents wokuhlanganisa |
Ibhrendi | I-Ruifu Chemical |
Into | Imininingwane |
Ukubukeka | I-Crystal Emhlophe noma Uketshezi Oluphuzi Olukhanyayo |
Ukuhlanzeka / Indlela Yokuhlaziya | >99.0% (GC) |
I-Melting Point | 32.0℃~36.0℃ |
Ukulahlekelwa Ekumisweni | <0.50% |
Ukuhlolwa Kwesixazululo (Ku-Acetone) | Kucacile futhi Kusobala |
I-Insoluble Matter Ku-acetone | Lutho |
Ukungcola Okuphelele | <1.00% |
Isitoreji | Vikela ukwakha ukukhanya bese ugcine endaweni epholile neyomile |
Izinga Lokuhlola | I-Enterprise Standard |
Ukusetshenziswa | I-Peptide Coupling Reagents |
Iphakheji:Ibhodlela, 25kg/Drum, noma ngokwezidingo zekhasimende.
Isimo Sesitoreji:Umswakama Uyazwela, gcina kude namanzi/umswakama.Gcina ezitsheni ezivaliwe endaweni epholile neyomile (2~8℃) kude nezinto ezingahambelani.
Ukuthumela:Thumela emhlabeni wonke nge-FedEx / DHL Express.Nikeza ukulethwa okusheshayo nokuthembekile.
1 Inhloso
Cacisa inqubo yokuhlolwa kwe-DCC.
2 Ibanga
Isebenza ekuhlolweni kwe-DCC enkampanini yaseRuifu.
3 Isisekelo
I-Chinese Pharmacopoeia 2005 edition, indinganiso yokulawula yangaphakathi yebhizinisi.
4. Isibopho
4.1 UMnyango Wekhwalithi unomthwalo wemfanelo wokuqeqesha nokuqondisa.
4.2 Umhlaziyi uzoba nesibopho sokusebenza okuqondile kanye nokunemba kwemiphumela yokuhlolwa.
5 Izinqubo Zokusebenza
5.1 Izici: Lo mkhiqizo uyikristalu emhlophe noma uketshezi oluphuzi olukhanyayo.
Thatha amagremu ayi-100 wesampula ulibeke ebhekhani, ulipholise lifike ezingeni lokushisa eliqandayo, bese ulishisa ukuze lincibilike.Qaphela umbala nekristalu ngokwehlukana
5.2 Indawo yokubanda
Faka isampula engu-15ml kushubhu yokuhlola engu-20ml.Isampula lincibilike ngokuphelele lapho lishisisa ku-45℃.Dlulisa ishubhu lokuhlola endaweni yokugeza yamanzi engu-25 ℃
Faka, gxuma bese ufaka uphawu lwe-thermometer.Njalo ngemizuzwana engama-30 kuze kube yilapho uketshezi luqina, bese kuthi njalo ngemizuzwana eyi-15,
Izinga lokushisa elibonisiwe yindawo yokuqandisa kuze kube yilapho izinga lokushisa lihlala lingashintshile cishe iminithi elingu-1.
5.3 Ukunqunywa kokuqukethwe
Ukunqunywa nge-chromatography yegesi (Isithasiselo se-Chinese Pharmacopoeia Edition 2005).
Ithuluzi: Kexiao GC1690 ikholomu yegesi yeChromatograph: ATSE-54
Izinga lokushisa lekholomu: 230℃ Igesi elithwala: i-nitrogen
Izinga lokushisa lokubona: 300 ℃ izinga lokushisa lomjovo: 280 ℃
Isilinganiso se-Shunt: 50:1 Umtshina: FID
Jova u-0.2ul wesixazululo sokuhlola ku-chromatograph imizuzu engu-15.Ilinganiswe ngendlela yendawo evamile.
5.4 Imiphumela
Ibalwa ngendlela yokwejwayelekile kwendawo, i-DCC akufanele ibe ngaphansi kwama-99.0%.
Amakhodi Engozi
R23/24/25 - Ubuthi ngokuhogela, ukuthintana nesikhumba futhi uma ugwinyiwe.
R34 - Ibangela ukusha
R40 - Ubufakazi obulinganiselwe bomphumela we-carcinogenic
R43 - Ingabangela ukuzwela ngokuthinta isikhumba
R41 - Ingozi yokulimala okubi emehlweni
R36/38 - Ukucasula emehlweni nasesikhumbeni.
R21 - Kuyingozi ukuthintana nesikhumba
R24 - Ubuthi uma uthinta isikhumba
R22 - Iyingozi uma igwinywe
I-R62 - Ingozi engaba khona yokukhubazeka kokuzala
R37/38 - Ukucasula uhlelo lokuphefumula kanye nesikhumba.
I-R10 - Iyavutha
I-R61 - Ingabangela ukulimala enganeni engakazalwa
R26 - Ubuthi Kakhulu ngokuhogela
R38 - Ukucasuka esikhumbeni
R20/22 - Kuyingozi ngokuhogela umoya futhi uma ugwinywe.
Incazelo Yokuphepha
S26 - Uma uthintana namehlo, geza ngokushesha ngamanzi amaningi futhi ufune iseluleko sezokwelapha.
I-S36/37/39 - Gqoka izingubo zokuzivikela ezifanele, amagilavu nokuvikela iso/ubuso.
S45 - Uma kwenzeka ingozi noma uzizwa ungaphilile, funa iseluleko sezokwelapha ngokushesha (bonisa ilebula noma nini lapho kunokwenzeka.)
S41 - Uma kuba nomlilo kanye / noma ukuqhuma ungawuphefumuli umusi.
I-S24 - Gwema ukuthintana nesikhumba.
I-S37/39 - Gqoka amagilavu afanelekile kanye nokuvikela iso/ubuso
I-S24/25 - Gwema ukuthintana nesikhumba namehlo.
I-S36 - Gqoka izingubo ezifanele zokuzivikela.
S16 - Gcina kude nemithombo yokuthungela.
I-S53 - Gwema ukuchayeka - thola imiyalelo ekhethekile ngaphambi kokusetshenziswa.
I-S28 - Ngemva kokuthinta isikhumba, geza ngokushesha ngensipho eningi.
Ama-ID e-UN UN 2922 8/PG 2
I-WGK Germany 3
I-RTECS FF2160000
I-FLUKA BRAND F AMAKHODI 3-8-10-21
TSCA Yebo
I-HS Code 2925290090
I-Hazard Class 6.1
Ukupakisha Iqembu II
Ubuthi be-LD50 ngomlomo kuNogwaja: 1110 mg/kg LD50 Igundane lesikhumba 71 mg/kg
I-DCC (N,N'-Dicyclohexylcarbodiimide, CAS: 538-75-0) isetshenziswa kukhemikhali ye-peptide njengento ehlanganisayo.Ikakhulukazi esetshenziselwa ukwakheka kokwenziwa kwama-peptides Ukufiphala kwama-amino acid.Isibonelo, ku-Fmoc-solid phase synthesis, iqembu le-carboxyl le-amino acid lakha isibopho se-amide neqembu le-amino lenye i-amino acid.Ukuze wenze iqembu le-carboxyl likwazi ukwamukela ukuhlaselwa kwama-nucleophiles, i-athomu ye-oksijini ekhokhiswe kabi idinga ukwenziwa isebenze ibe yiqembu elingcono elishiyayo, futhi i-DCC idlala le ndima.I-athomu ye-oxygen yeqembu le-carboxyl ku-amino acid isebenza njenge-nucleophile ukuhlasela i-athomu ye-carbon phakathi ne-molecule ye-DCC ukuze i-DCC ihlangane neqembu le-carboxyl yakhe isakhiwo se-ester, okwenza ukuhlasela kwe-nucleophilic kweqembu le-amino. kulula ukwenza i-coupling reagent.
I-DCC isetshenziselwa ukuhlanganiswa nokuqeda amanzi emzimbeni we-amikacin nama-amino acid.iyi-agent enhle yokushisa ephansi ye-biochemical dehydrating futhi isetshenziselwa ukuhlanganiswa kwama-acids, ama-anhydrides, ama-aldehydes, ama-ketones, njll. E-Japan, ama-dehydrating agents asetshenziselwa i-akhawunti ye-glutathione ye-90% yokusetshenziswa okuphelele.Uma umkhiqizo usetshenziswa njenge-ejenti yokuqeda amanzi emzimbeni kanye ne-condensing, ungasabela ngesikhathi esifushane ekamelweni lokushisa, futhi umkhiqizo ngemva kokusabela yi-dicyclohexylurea.Njengoba ukuncibilika komkhiqizo ku-solvent ye-organic kuncane kakhulu, umkhiqizo wokusabela kulula ukuwuhlukanisa;ngesikhathi esifanayo, ngoba umkhiqizo unzima ukuncibilika emanzini, ukusabela kusengaqhubeka ngisho nesisombululo esinamanzi.Umkhiqizo usetshenziselwa ukuhlanganiswa kwama-peptides nama-nucleic acid.Ukusetshenziswa kwalo mkhiqizo kungahlanganisa kalula ama-peptide avela kumakhompiyutha anamaqembu e-carboxyl yamahhala futhi ahlanganiswe namaqembu amahhala we-amino ekamelweni lokushisa, futhi isivuno siphezulu kakhulu.Isetshenziselwa ukukhiqizwa kwe-hypertensives kanye ne-cyclic adenosine monophosphate.esetshenziswa njenge-biochemical reagent kanye ne-organic synthesis dehydration condensing agent.