I-Deoxycholic Acid CAS 83-44-3 Purity >98.0% (T) (HPLC)
I-Shanghai Ruifu Chemical Co., Ltd. ingumkhiqizi ohamba phambili we-Deoxycholic Acid (CAS: 83-44-3) enekhwalithi ephezulu.I-Ruifu Chemical inganikeza ukulethwa komhlaba wonke, intengo encintisanayo, isevisi enhle kakhulu, amanani amancane kanye nenqwaba etholakalayo.Thenga i-Deoxycholic Acid,Please contact: alvin@ruifuchem.com
Igama Lekhemikhali | I-Deoxycholic Acid |
Omqondofana | I-Choleic Acid;I-DCA;I-3α,12α-Dihydroxy-5β-Cholanic Acid;7-Deoxycholic acid;I-Desoxycholic Acid;I-Cholanoic Acid;Ukungcola kwe-Ursodeoxycholic Acid |
Isimo Sesitoko | Ku-Stock, Commercial Production |
Inombolo ye-CAS | 83-44-3 |
I-Molecular Formula | I-C24H40O4 |
Isisindo samangqamuzana | 392.58 g/mol |
I-Melting Point | 172.0~178.0℃ |
Ukuncibilika kwamanzi | Incibilika Kancane Emanzini |
I-Solubility ku-Methanol | Cishe Ukungafihli |
Ukuzinza | Izinzile.Okuvuthayo.Akuhambisani nama-Ejenti Oxidizing Aqinile. |
I-COA ne-MSDS | Iyatholakala |
Isampula | Iyatholakala |
Umsuka | Shanghai, China |
Ibhrendi | I-Ruifu Chemical |
Izinto | Imininingwane | Imiphumela |
Ukubukeka | I-Crystal Powder Emhlophe | I-Crystal Powder Emhlophe |
I-Melting Point | 172.0~178.0℃ | 175.2℃ |
Ukuzungezisa Okuthile [a]20/D | +53.0° ukuya +57.0° (C=1 ku-EtOH) | +54.5° |
Ukulahlekelwa Ekumisweni | <0.50% | 0.07% |
Izinsalela ekushiseni | <0.20% | 0.1% |
I-Cholic Acid (TLC) | <0.50% | 0.3% |
Izinsimbi Ezisindayo (njenge-Pb) | ≤20ppm | <10ppm |
Ukuhlanzeka / Indlela Yokuhlaziya | >98.0% (HPLC) | 98.56% |
I-Infrared Spectrum | Ihambisana Nesakhiwo | Iyahambisana |
Isiphetho | Umkhiqizo uhloliwe futhi uthobela imininingwane enikeziwe | |
I-Shelf Life | Iminyaka engu-2 Lapho Igcinwe Ngokufanele |
Iphakheji:Ibhodlela eliFluorinated, isikhwama se-Aluminium foil, 25kg/Cardboard Drum, noma ngokwezidingo zekhasimende.
Isimo Sesitoreji:Gcina isitsha sivalwe ngokuqinile futhi usigcine endaweni epholile, eyomile futhi enomoya omuhle kude nezinto ezingahambelani.Vikela ekukhanyeni nakumswakama.Gcina kude nama-oxidizing agents.
Ukuthumela:Zilethe emhlabeni wonke ngendiza, yi-FedEx/DHL Express.Nikeza ukulethwa okusheshayo nokuthembekile.
Indlela Yokuthenga?Sicela uxhumaneDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
Iminyaka engu-15 Yokuhlangenwe nakho?Sinesipiliyoni seminyaka engaphezu kwe-15 ekwakhiweni nasekuthumeleni kwamanye amazwe uhla olubanzi lwezinga eliphezulu lokuxhumanisa imithi noma amakhemikhali amahle.
Izimakethe Eziyinhloko?Thengisa emakethe yasekhaya, eNyakatho Melika, eYurophu, eNdiya, eKorea, eJapane, e-Australia, njll.
Izinzuzo?Ikhwalithi ephezulu, intengo ethengekayo, izinsizakalo ezichwepheshile nokusekelwa kobuchwepheshe, ukulethwa okusheshayo.
IkhwalithiIsiqiniseko?Isistimu yokulawula ikhwalithi eqinile.Imishini yobuchwepheshe yokuhlaziya ifaka i-NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, NOMA, KF, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, njll.
Amasampula?Imikhiqizo eminingi inikeza amasampula wamahhala wokuhlolwa kwekhwalithi, izindleko zokuthumela kufanele zikhokhelwe amakhasimende.
Ukuhlolwa Kwemboni?Wamukelekile ekucwaningweni kwemboni.Sicela wenze i-aphoyintimenti kusengaphambili.
I-MOQ?Ayikho i-MOQ.I-oda elincane liyamukeleka.
Isikhathi sokuthumela? Uma kungaphakathi kwesitoko, ukulethwa kwezinsuku ezintathu kuqinisekisiwe.
Ezokuthutha?By Express (FedEx, DHL), by Air, by Sea.
Amadokhumenti?Ngemuva kwenkonzo yokuthengisa: I-COA, i-MOA, i-ROS, i-MSDS, njll.
Custom Synthesis?Ingahlinzeka ngezinsizakalo zokwenziwa ngokwezifiso ukuze zilingane kangcono nezidingo zakho zocwaningo.
Imigomo Yokukhokha?I-invoyisi ye-Proforma izothunyelwa kuqala ngemva kokuqinisekiswa kwe-oda, kufakwe nemininingwane yethu yasebhange.Inkokhelo nge-T/T (Telex Transfer), PayPal, Western Union, njll.
Izimpawu Zengozi Xn - Ziyingozi
Amakhodi Engozi R22 - Ayingozi uma uwagwinyile
R36/37/38 - Ukucasula amehlo, uhlelo lokuphefumula kanye nesikhumba.
R37 - Ukucasula uhlelo lokuphefumula
R20/21/22 - Kuyingozi ngokuhogela, ukuthintana nesikhumba futhi uma ukugwinyile.
Incazelo Yezokuphepha S26 - Uma uthintana namehlo, geza ngokushesha ngamanzi amaningi futhi ufune iseluleko sezokwelapha.
I-S36 - Gqoka izingubo ezifanele zokuzivikela.
I-S37/39 - Gqoka amagilavu afanelekile kanye nokuvikela iso/ubuso
S22 - Ungaphefumuli uthuli.
Omazisi be-UN UN1230 - isigaba 3 - PG 2 - Methanol, isisombululo
I-WGK Germany 3
I-RTECS FZ2100000
TSCA Yebo
I-HS Code 2918190090
Ubuthi be-LD50 bomlomo kumagundane: 1gm/kg
I-Deoxycholic Acid (CAS: 83-44-3) ivamise ukuhlanganiswa ne-glycine noma i-taurine futhi isebenze njengesihlanzi emulsification yamafutha ukuze amunce amathumbu.
I-Deoxycholic Acid yathuthukiswa yi-Kythera biopharpharmaceuticals, Inc., ngo-April 2015 yi-US Food and Drug Administration (FDA).Kugunyazwe njengomuthi wokuqala wendawo oncibilikisa i-lipid emhlabeni.I-Deoxycholic acid iwuhlobo lwe-bile acid yamahhala ekhona ku-bile, enomsebenzi oqinile wangaphezulu, ingabhubhisa futhi incibilikise ulwelwesi lwamangqamuzana, futhi yehlise ukuncibilika kwamafutha amancane endawo angaphansi kwesikhumba.Ezivivinyweni zomtholampilo, i-deoxycholic acid yayisebenza kahle ekuqedeni amafutha angaphansi futhi ithuthukise ukubukeka okuphelele uma kuqhathaniswa ne-placebo.
I-Deoxycholic Acid iyi-asidi yesibili ye-bile ehilelekile emulsification nase-solubilization yamafutha okudla.Isixazululo esijovwayo esingu-10 mg/mL se-Deoxycholic Acid eyenziwe ngamakhemikhali siboniswa emazweni ahlukahlukene, kuhlanganise ne-USA (Kybella TM) [9] kanye nambalwa ngaphakathi kwe-Europe/EU (Belkyra TM) ukuze kuthuthukiswe ukubukeka kwe-convexity ephansi noma eqinile ehambisanayo. nge-SMF kubantu abadala, lapho okwamanje kuwukuphela kwendlela yokwelapha evunyelwe kancane yokukhonkwane okungaphansi.
I-sodium Deoxycholate, usawoti we-sodium we-Deoxycholic Acid, uvame ukusetshenziswa njengesihlanzi sebhayoloji ukuze kuhlanjululwe amaseli kanye ne-solubilise izingxenye zamaselula kanye ne-membrane.
Njenge-bile acid, i-Deoxycholic Acid ifaka amafutha emathunjini.I-deoxycholic acid eyenziwe ngokwenziwa, lapho ijova, ivuselela ukuwohloka okuhlosiwe kwamangqamuzana e-adipose ngokuphazamisa ulwelwesi lwamaseli futhi kubangele i-adipocytolysis.Lokhu kubangela ukusabela kokuvuvukala nokususwa kwezinsalela zezicubu ze-adipose ngama-macrophages.Izenzo ze-Deoxycholic Acid zincishiswa yi-albumin kanye namaprotheni ahlobene nezicubu, ngakho-ke umphumela wawo ukhawulelwe kuzicubu zamafutha angaphansi kwamaprotheni ampofu.Izicubu ezicebile ngamaprotheni njengemisipha nesikhumba azithintwa yi-deoxycholic acid, okunomthelela ekuphepheni kwayo.