I-Diethyl(3-pyridyl)borane CAS 89878-14-8 Ubumsulwa >99.0% (HPLC) I-Abiraterone Acetate Intermediate Factory
Ukunikezwa Komkhiqizi, Ukuhlanzeka Okuphezulu, Ukukhiqizwa Kwezohwebo
Igama Lekhemikhali: Diethyl(3-pyridyl)borane
I-CAS: 89878-14-8
Igama Lekhemikhali | I-Diethyl (3-pyridyl) borane |
Omqondofana | 3-(Diethylboryl)pyridine |
Inombolo ye-CAS | 89878-14-8 |
Inombolo yeCAT | I-RF-PI674 |
Isimo Sesitoko | Esitokweni, Isikali Sokukhiqiza Sifinyelela Kumathani |
I-Molecular Formula | I-C9H14BN |
Isisindo samangqamuzana | 147.03 |
I-Melting Point | 159.0~164.0℃ (okhanyisiwe) |
Ibhrendi | I-Ruifu Chemical |
Into | Imininingwane |
Ukubukeka | Impushana Emhlophe |
I-Infrared Spectrum | Ivumelana Nesakhiwo |
Ukuhlanzeka / Indlela Yokuhlaziya | >99.0% (HPLC) |
Ukulahlekelwa Ekumisweni | ≤0.50% |
Izinsalela Ekushiseni | ≤0.50% |
Ukungcola Okukodwa | ≤0.50% |
Ukungcola Okuphelele | <1.00% |
Izinsimbi Ezisindayo (njenge-Pb) | ≤20ppm |
Izinga Lokuhlola | I-Enterprise Standard |
Ukusetshenziswa | I-Intermediate ye-Abiraterone Acetate (CAS: 154229-18-2) |
Iphakheji: Ibhodlela, isikhwama se-Aluminium foil, 25kg/Cardboard Drum, noma ngokwezidingo zekhasimende.
Isimo Sesitoreji:Gcina ezitsheni ezivaliwe endaweni epholile neyomile;Vikela ekukhanyeni nakumswakama.
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I-Diethyl(3-pyridyl)borane (CAS: 89878-14-8) iphakathi kwe-Abiraterone Acetate (CAS: 154229-18-2).Ngo-April 2011, i-United States FDA igunyaze i-Abiraterone Acetate ngokuhambisana ne-steroid prednisone yokwelapha umdlavuza wendlala yesinye we-metastatic castration-resistant (mCRPC) ezigulini ezake zelashwa nge-docetaxel equkethe uhlobo lwesifo sesigaba sekwephuzile.Umuthi, owamakethwa ngaphansi kwegama lokuhweba elithi Zytiga, ekuqaleni watholwa abacwaningi baseCancer Research UK Center for Cancer Therapeutics ngo-1990, wathuthukiswa yiCougar Biotechnology, futhi wagcina uthengiswa uJohnson & Johnson ngemuva kokutholwa kwawo kweCougar ngo-2009.