(Dimethylamino)i-acetaldehyde I-Diethyl Acetal CAS 3616-56-6 Ubumsulwa >99.0% (GC) I-Afatinib Dimaleate Intermediate Factory

Incazelo emfushane:

Igama: (i-Dimethylamino) i-acetaldehyde i-Diethyl Acetal

Synonimes: 2,2-Diethoxy-N,N-Dimethylethylamine

I-CAS: 3616-56-6

Ubumsulwa: >99.0% (GC)

Ukubukeka: Uketshezi Olucacile Olungenambala

I-Intermediate ye-Afatinib Dimaleate (CAS: 850140-73-7)

Ikhwalithi Ephezulu, Ukukhiqizwa Kwezohwebo

E-Mail: alvin@ruifuchem.com


Imininingwane Yomkhiqizo

Imikhiqizo Ehlobene

Omaka bomkhiqizo

Incazelo:

Chemical Properties:

Igama Lekhemikhali (I-Dimethylamino) i-acetaldehyde i-Diethyl Acetal
Omqondofana 2,2-Diethoxy-N,N-Dimethylethylamine;N-(2,2-Diethoxyethyl)dimethylamine;2,2-Diethoxy-N,N-Dimethylethhan-1-Amine
Inombolo ye-CAS 3616-56-6
Inombolo yeCAT I-RF-PI2031
Isimo Sesitoko Esitokweni, Isikali Sokukhiqiza Sifinyelela Kumathani
I-Molecular Formula I-C8H19NO2
Isisindo samangqamuzana 161.25
Ukuzwela Kuyazwela Umswakama
Iphuzu elibilayo 60℃/5 mmHg
I-Flash Point 45℃
Ibhrendi I-Ruifu Chemical

Imininingwane:

Into Imininingwane
Ukubukeka Uketshezi Olucacile Olungenambala
Ukuhlanzeka / Indlela Yokuhlaziya >99.0% (GC)
I-Refractive Index N20/D 1.410~1.414
I-Gravity ethize (20/20℃) 0.865~0.870
I-Proton NMR Spectrum Ivumelana Nesakhiwo
Ukungcola Okuphelele <1.00%
Izinsimbi Ezisindayo (njenge-Pb) ≤20ppm
Izinga Lokuhlola I-Enterprise Standard
Ukusetshenziswa Abalamuli Bezemithi;I-Afatinib Dimaleate;I-Sumatriptan

Iphakheji nesitoreji:

Iphakheji: Ibhodlela Elifakwe Fluorinated, 25kg/Drum, noma ngokwezidingo zekhasimende

Isimo Sesitoreji:Gcina ezitsheni ezivaliwe endaweni epholile neyomile;Vikela ekukhanyeni nakumswakama

Izinzuzo:

1

I-FAQ:

Isicelo:

(I-Dimethylamino) i-acetaldehyde i-Diethyl Acetal (i-CAS: i-3616-56-6) isetshenziswa njengabaphakathi kwezemithi.(I-Dimethylamino) i-acetaldehyde I-Diethyl Acetal ingasetshenziswa ekuhlanganiseni kwe-Afatinib Dimaleate (CAS: 850140-73-7), i-Sumatriptan (CAS: 103628-46-2).I-Afatinib (igama lokuhweba elithi Gilotrif e-US kanye ne-Giotrif eYurophu, ngaphambili eyayiyi-Tomtovok ne-Tovok) iyisidakamizwa esigunyazwe e-United States, e-Europe, e-Taiwan, e-Mexico, e-Chile nase-Japan kanye nakwamanye amazwe ukuze zelashwe umugqa wokuqala weziguli ezihlukile. izinhlobo ze-metastatic (EGFR mutation positive) non-small cell lung carcinoma (NSCLC), eyakhiwe ngu-Boehringer Ingelheim.I-Afatinib isebenza njenge-covalent inhibitor engaphenduki ye-receptor tyrosine kinases epidermal growth factor receptor (EGFR) kanye ne-erbB-2 (HER2).I-Sumatriptan yayiyi-triptan yokuqala evunyelwe (1991) yokwelashwa okunamandla kwekhanda le-migraine.Ine-lowstoral bioavailability phakathi kwawo wonke ama-triptan ngenxa ye-lowlipophilicity yayo.Ukutholakala kwezinhlobo eziningi zemithamo ehlukene (okungukuthi, ithebhulethi yomlomo, umjovo we-SC, ukubunjwa kwesifutho samakhala, kanye ne-suppository) kuvumela ukuguquguquka kokwelashwa okuthungayo ngokwezidingo zesiguli ngasinye, okwenza ama-sumatriptans abe umuthi owusizo kakhulu ekwelapheni okukhulu kwe-migraine. ikhanda.I-Sumatriptan futhi ine-fastonset yesenzo esheshayo ngomjovo we-SC noma ukuphathwa kwesifutho samakhala.

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