I-Docetaxel CAS 114977-28-5 Assay 98.0%~102.0%
I-Shanghai Ruifu Chemical Co., Ltd. ingumkhiqizi ohamba phambili we-Docetaxel (Taxotere) (CAS: 114977-28-5) enekhwalithi ephezulu.I-Ruifu Chemical inganikeza ukulethwa komhlaba wonke, intengo encintisanayo, isevisi enhle kakhulu, amanani amancane kanye nenqwaba etholakalayo.Thenga i-Docetaxel,Please contact: alvin@ruifuchem.com
| Igama Lekhemikhali | I-Docetaxel |
| Omqondofana | Taxotere;I-Taxotere Anhydrous;I-Docetaxel Anhydrous;I-N-Debenzoyl-N-tert-Butoxycarbonyl-10-Deacetyltaxol;RP-56976 |
| Isimo Sesitoko | Ku-Stock, Commercial Production |
| Inombolo ye-CAS | 114977-28-5 |
| I-Molecular Formula | I-C43H53NO14 |
| Isisindo samangqamuzana | 807.89 g/mol |
| I-Melting Point | 186.0~192.0℃(dec.) |
| Ukuminyana | 1.38 |
| Ukuncibilika | Incibilika kakhulu ku-Acetone, i-Dimethylformamide.Incibilika ku-Ethanol, Dichloromethane, Methanol.Ayincibiliki Emanzini |
| I-COA ne-MSDS | Iyatholakala |
| Umsuka | Shanghai, China |
| Ibhrendi | I-Ruifu Chemical |
| Izinto | Imininingwane | Imiphumela |
| Ukubukeka | I-Crystalline Powder Emhlophe | I-Crystalline Powder Emhlophe |
| Ukuhlonza | I-IR ne-HPLC | Kuyavumelana |
| Ukuzungezisa Okuthile [a]20/D | -42.0° ukuya -45.0° (C=1 ku-EtOH) | -43.1° |
| Ukulahlekelwa Ekumisweni | <3.00% | 2.05% |
| Izinsalela ekushiseni | <0.10% | 0.04% |
| Izinsimbi Ezisindayo (Pb) | ≤20ppm | <20ppm |
| I-Arsenic (As) | ≤1.5ppm | <1.5ppm |
| Izinto Ezihlobene | ||
| Ukungcola Okukodwa Okukhulu | <0.50% | <0.50% |
| Ukungcola Okuphelele | <1.00% | <1.00% |
| Ukuhlolwa Komkhawulo We-Microbial | ||
| I-TAMC | ≤100cfu/g | <100cfu/g |
| I-TYMC | ≤10cfu/g | <10cfu/g |
| Ama-bacterium Endotoxins | ≤0.3IU/mg | <0.3IU/mg |
| Indlela Yokuhlola / Yokuhlaziya | 98.0%~102.0% (Ngesisekelo Esingenayo I-Anhydrous kanye Ne-Solvent-Free) | 100.9% |
| Isiphetho | Umkhiqizo uhloliwe futhi uthobela imininingwane enikeziwe | |
Iphakheji:Ibhodlela eliFluorinated, isikhwama se-Aluminium foil, 25kg/Cardboard Drum, noma ngokwezidingo zekhasimende.
Isitoreji:Gcina isiqukathi sivalwe ngokuqinile futhi usigcine endaweni epholile, eyomile (2~8℃) nengena umoya omuhle kude nezinto ezingahambelani.Vikela ekukhanyeni nakumswakama.Akuhambisani nama-oxidizing agents aqinile.
Ukuthumela:Zilethe emhlabeni wonke ngendiza, yi-FedEx/DHL Express.Nikeza ukulethwa okusheshayo nokuthembekile.
Indlela Yokuthenga?Sicela uxhumaneDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
Iminyaka engu-15 Yokuhlangenwe nakho?Sinesipiliyoni seminyaka engaphezu kwe-15 ekwakhiweni nasekuthumeleni kwamanye amazwe uhla olubanzi lwezinga eliphezulu lokuxhumanisa imithi noma amakhemikhali amahle.
Izimakethe Eziyinhloko?Thengisa emakethe yasekhaya, eNyakatho Melika, eYurophu, eNdiya, eKorea, eJapane, e-Australia, njll.
Izinzuzo?Ikhwalithi ephezulu, intengo ethengekayo, izinsizakalo ezichwepheshile nokusekelwa kobuchwepheshe, ukulethwa okusheshayo.
IkhwalithiIsiqiniseko?Isistimu yokulawula ikhwalithi eqinile.Imishini yobuchwepheshe yokuhlaziya ifaka i-NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, NOMA, KF, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, njll.
Amasampula?Imikhiqizo eminingi inikeza amasampula wamahhala wokuhlolwa kwekhwalithi, izindleko zokuthumela kufanele zikhokhelwe amakhasimende.
Ukuhlolwa Kwemboni?Wamukelekile ekucwaningweni kwemboni.Sicela wenze i-aphoyintimenti kusengaphambili.
I-MOQ?Ayikho i-MOQ.I-oda elincane liyamukeleka.
Isikhathi sokuthumela? Uma kungaphakathi kwesitoko, ukulethwa kwezinsuku ezintathu kuqinisekisiwe.
Ezokuthutha?By Express (FedEx, DHL), by Air, by Sea.
Amadokhumenti?Ngemuva kwenkonzo yokuthengisa: I-COA, i-MOA, i-ROS, i-MSDS, njll.
Custom Synthesis?Ingahlinzeka ngezinsizakalo zokwenziwa ngokwezifiso ukuze zilingane kangcono nezidingo zakho zocwaningo.
Imigomo Yokukhokha?I-invoyisi ye-Proforma izothunyelwa kuqala ngemva kokuqinisekiswa kwe-oda, kufakwe nemininingwane yethu yasebhange.Inkokhelo nge-T/T (Telex Transfer), PayPal, Western Union, njll.
Izimpawu Zengozi Xi - Iyacasula
Amakhodi Engozi
R36/37/38 - Ukucasula amehlo, uhlelo lokuphefumula kanye nesikhumba.
I-R61 - Ingabangela ukulimala enganeni engakazalwa
Incazelo Yokuphepha
S26 - Uma uthintana namehlo, geza ngokushesha ngamanzi amaningi futhi ufune iseluleko sezokwelapha.
I-S36/37 - Gqoka izingubo zokuzivikela ezifanele namagilavu.
I-S53 - Gwema ukuchayeka - thola imiyalelo ekhethekile ngaphambi kokusetshenziswa.
S45 - Uma kwenzeka ingozi noma uzizwa ungaphilile, funa iseluleko sezokwelapha ngokushesha (bonisa ilebula noma nini lapho kunokwenzeka.)
Ama-ID e-UN 1544
I-WGK Germany 3
I-RTECS DA4172750
I-HS Code 2932999029
I-Hazard Class 6.1(b)
Ukupakisha Iqembu III
Ubuthi be-LD50 obufakwe enjeni: 2500ug/kg
I-Docetaxel (Taxotere) (CAS: 114977-28-5) ethengiswa njenge-Taxotere noma i-Docecad, imithi esungulwe kahle ye-anti-mitotic chemotherapy esebenza ngokuphazamisa ukuhlukaniswa kwamaseli.I-Docetaxel igunyazwe yi-FDA ukuze zelashwe umdlavuza webele osuthuthuke kakhulu noma ometastatic, umdlavuza wekhanda nentamo, umdlavuza wesisu, umdlavuza wendlala yesinye i-hormone-refractory kanye nomdlavuza wamaphaphu ongewona wamaseli amancane.I-Docetaxel ingasetshenziswa njenge-ejenti eyodwa noma ihlanganiswe nezinye izidakamizwa ze-chemotherapeutic njengoba kukhonjisiwe kuye ngohlobo oluthile lomdlavuza kanye nesiteji.I-Docetaxel iyilungu lesigaba semithi ye-taxane, ehlanganisa nemithi ye-chemotherapeutic paclitaxel.Nakuba i-docetaxel ihlala inamandla ngokuphindwe kabili njenge-paclitaxel (ngenxa yomphumela we-docetaxel ku-centrosome ye-mitotic spindle), ama-taxane amabili abonwe esebenza ngokulinganayo.Izindatshana ezimbalwa zakamuva zithole "abukho ubufakazi bokuthi izinhlobo zemithi eziqukethe i-docetaxel ziletha izinzuzo ezinkulu kunalezo ezifaka i-paclitaxel."Ngenkathi ukusebenza kahle phakathi kwama-ejenti amabili kuye kwaqashelwa ukuthi kuyalingana, i-paclitaxel ingabangela imiphumela emibi embalwa.Ukwengeza, kuye kwaphawulwa ukuthi i-docetaxel ijwayele ukumelana nezidakamizwa zeselula ngokusebenzisa izindlela ezihlukahlukene ezahlukene.
1. I-Docetaxel umuthi osungulwe kahle ngokomtholampilo we-anti mitotic chemotherapy (okungukuthi, uphazamisa ukuhlukana kwamaseli).
2. I-Docetaxel isetshenziswa kakhulukazi ekwelapheni umdlavuza webele, wesibeletho, kanye noweseli ongewona omncane wamaphaphu.
3. I-Docetaxel inesimangalo esigunyazwe yi-FDA sokwelashwa kweziguli ezinomdlavuza wamaphaphu othuthuke kakhulu endaweni, noma we-metastatic noma ongewona wamaseli amancane eziye zathola ukwelashwa ngamakhemikhali okusekelwe ku-anthracycline futhi ezihlulekile ukumisa ukuqhubeka komdlavuza noma ezibuye zabuyela emuva.I-European doce-taxel egunyaza ukusetshenziswa kumdlavuza wendlala yesinye we-hormone-refractory.
4. I-Docetaxel ibhekwa njengengcono kune-, njenge-antimicrotubule eyi-cytotoxic.
