I-Doxorubicin Hydrochloride CAS 25316-40-9 API USP Standard Factory High Purity
Umkhiqizi onokuhlanzeka Okuphezulu kanye Nekhwalithi Ezinzile
Igama Lekhemikhali: Doxorubicin Hydrochloride
I-CAS: 25316-40-9
I-Antitumor Antibiotic Agent.Ivimbela i-DNA Topoisomerase II
Ikhwalithi ephezulu ye-API, Ukukhiqiza Kwezentengiso
Igama Lekhemikhali | I-Doxorubicin Hydrochloride |
Omqondofana | I-Doxorubicin HCl;I-Adriamycin HCL;IHydroxydaunorubicin Hydrochloride |
Inombolo ye-CAS | 25316-40-9 |
Inombolo yeCAT | I-RF-API38 |
Isimo Sesitoko | Esitokweni, Isikali Sokukhiqiza Sifinyelela Kumathani |
I-Molecular Formula | I-C27H30ClNO11 |
Isisindo samangqamuzana | 579.98 |
Ibhrendi | I-Ruifu Chemical |
Into | Imininingwane |
Ukubukeka | I-Orange-Red Crystalline Powder;Abukho ubufakazi obubonakalayo bokungcoliswa yindaba yangaphandle |
Ukuncibilika | Incibilika emanzini kanye ne-methanol;inyibilika kancane ku-ethanol;ayincibiliki ku-acetone |
Ukuhlonza A | I-spectrum ye-IR ihambisana ne-spectrum ye-IR yezinga lesithenjwa |
Ukuhlonza B | Isikhathi sokugcinwa sesiqongo se-doxorubicin ku-chromatogram yokulungiselelwa kwe-Assay sihambisana naleso esiku-chromatogram yokulungiselelwa Okujwayelekile, njengoba kutholwe ku-Assay. |
pH | 4.0~5.5 |
Okuqukethwe Amanzi | ≤4.0% |
Izinto Ezihlobene | |
Ukungcola A (Doxorubicinol) | ≤0.50% |
Noma Ikuphi Okunye Ukungcola Okungaziwa | ≤0.20% |
Ukungcola Okungaziwa Okuphelele | ≤0.50% |
Ukungcola Okuphelele | ≤1.0% |
Isivivinyo | 98.0%~102.0% we-C27H30ClNO11 abalwe ngesisekelo se-anhydrous, i-solvent-free |
Izincibilikisi Ezisele | |
I-acetone | ≤0.50% |
I-Acetone + Ethanol | ≤2.5% |
I-Methanol | ≤0.30% |
I-Dichloromethane | ≤0.06% |
Izinga Lokuhlola | I-United States Pharmacopeia (USP) Reference Standard |
Ukusetshenziswa | I-Active Pharmaceutical Ingredient (API) |
Iphakheji: Ibhodlela, isikhwama se-Aluminium foil, isigubhu seCardboard, 25kg/Drum, noma ngokwezidingo zekhasimende.
Isimo Sesitoreji:Gcina ezitsheni ezivaliwe endaweni epholile neyomile;Vikela ekukhanyeni, umswakama kanye nezinambuzane.
I-Shanghai Ruifu Chemical Co., Ltd. ingumkhiqizi oholayo kanye nomphakeli we-Doxorubicin Hydrochloride (CAS: 25316-40-9) enekhwalithi ephezulu.I-Doxorubicin hydrochloride, i-cytotoxic anthracycline antibiotic, iyi-ejenti ye-anti-cancer chemotherapy.I-Doxorubicin hydrochloride iyi-DNA yomuntu enamandla i-topoisomerase I kanye ne-topoisomerase II inhibitor ene-IC50s ka-0.8 μM no-2.67 μM, ngokulandelana.I-Doxorubicin hydrochloride idala i-apoptosis kanye ne-autophagy.I-Doxorubicin iyi-ejenti enamandla ye-antitumour esebenza ngokumelene nezinhlobo eziningi zezifo ezibulalayo, okuhlanganisa i-leukemia, i-sarcomas, umdlavuza webele, umdlavuza wamaphaphu omncane kanye nomdlavuza wesibeletho.