I-Edaravone CAS 89-25-8;I-1-Pheny-3-Methyl-5-Pyrazolone (PMP) Ukuhlanzeka Okuphezulu
Nikeza Ngokuhlanzeka Okuphezulu kanye Nekhwalithi Ezinzile
Igama: Edaravone
CAS: 89-25-8
Igama | Edaravone |
Omqondofana | I-1-Pheny-3-Methyl-5-Pyrazolone (PMP);I-MCI-186 |
Inombolo ye-CAS | 89-25-8 |
Inombolo yeCAT | I-RF-PI237 |
Isimo Sesitoko | Esitokweni, Isikali Sokukhiqiza Sifinyelela Kumathani |
I-Molecular Formula | I-C10H10N2O |
Isisindo samangqamuzana | 174.2 |
Ukuminyana | 1.12 g/cm3 |
Ibhrendi | I-Ruifu Chemical |
Into | Imininingwane |
Ukubukeka | I-Crystal Ephuzi Ekhanyayo noma I-Powder |
Ubumsulwa | ≥99.0% |
I-Melting Point | 127.0 ~ 130.0℃ |
Ukulahlekelwa Ekumisweni | ≤0.50% |
Izinsalela ekushiseni | ≤0.30% |
Ukungcola Okukodwa | ≤0.50% |
Ukungcola Okuphelele | ≤1.0% |
Izinsimbi Ezisindayo | ≤20ppm |
Ukuncibilika | Incibilika ku-5% Hydrochloric Acid |
Izinga Lokuhlola | I-Enterprise Standard |
Ukusetshenziswa | I-API;Pharmaceutical Intermediates |
Iphakheji: Ibhodlela, isikhwama se-Aluminium foil, isigubhu seCardboard, 25kg/Drum, noma ngokwezidingo zekhasimende.
Isimo Sesitoreji:Gcina ezitsheni ezivaliwe endaweni epholile neyomile;Vikela ekukhanyeni, umswakama kanye nezinambuzane.
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I-Edaravone (i-CAS 89-25-8) iyi-scavenger entsha yamahhala enamandla esetshenziselwa ukwelapha iziguli ezine-acute brain infarction.I-Edaravone iyi-scavenger enamandla kanye ne-antioxidant ekwazi ukuvikela emiphumeleni ye-ischemia, mhlawumbe ngokuvimbela uhlelo lwe-lipoxygenase.Ivikela ku-MPTP-induced neurotoxicity.Ivimbela i-autophagy.I-Edaravone yathengiswa eJapan ukuze kuthuthukiswe ukululama kwe-neurologic kulandela ukuhlaselwa kobuchopho okunamandla.Njengamanje, ama-ejenti amaningana ahlukaniswa njengama-neuroprotectants futhi asebenza ngezindlela ezihlukahlukene (ukuvimbela ukukhululwa kwe-glutamate, ukuvinjelwa kweziteshi ze-calcium, i-lazaroids) adayiswe ukuze aphathe imiphumela yokulimala kobuchopho ngenxa yokuhlukumezeka, ischemia noma ukuboshwa kwenhliziyo.I-Edavarone iyi-antioxidant yokuqala enomsebenzi wokukhipha ama-radical wamahhala ozokwethulwa kule pathology.