I-Entecavir CAS 142217-69-4 API Factory High Quality Anti-HBV

Incazelo emfushane:

Igama: Entecavir

I-CAS: 142217-69-4

Ukubukeka: I-Crystalline Powder Emhlophe

I-antiviral esetshenziswa ekwelapheni i-Hepatitis B Infection

Ikhwalithi ephezulu ye-API, Ukukhiqiza Kwezentengiso

Inquiry: alvin@ruifuchem.com

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Incazelo:

Ukunikezela Komkhiqizi Ngokuhlanzeka Okuphezulu kanye Nekhwalithi Ezinzile
Igama Lekhemikhali: I-Entecavir
I-CAS: 142217-69-4
I-antiviral esetshenziswa ekwelapheni i-Hepatitis B Infection
Ikhwalithi ephezulu ye-API, Ukukhiqiza Kwezentengiso

Chemical Properties:

Igama Lekhemikhali	I-Entecavir
Omqondofana	2-Amino-1,9-dihydro-9-[(1S,3R,4S)-4-hydroxy-3-(hydroxymethyl)-2-methylenecyclopenyl]-6H-purin-6-one
Inombolo ye-CAS	142217-69-4
Inombolo yeCAT	I-RF-API80
Isimo Sesitoko	Esitokweni, Isikali Sokukhiqiza Sifika Emakhulwini Amakhilogremu
I-Molecular Formula	I-C12H15N5O3
Isisindo samangqamuzana	277.28
I-Melting Point	249.0~252.0℃
Ibhrendi	I-Ruifu Chemical

Imininingwane:

Into	Imininingwane
Ukubukeka	I-Crystalline Powder Emhlophe
Ukuhlonza IR	I-spectrum yokumuncwa kwe-infraed yesampula yokuhlola kufanele ihambisane nezinga lereferensi
Ukuhlonza HPLC	Isikhathi sokugcinwa kwesampula yokuhlola sihambisana naleso sezinga lesithenjwa
pH	5.5~7.5
I-Specific Optical Rotation	+24.0°-+28.0° (DMF: MeOH=1:1 C=1%)
Izinto Ezihlobene
Ukungcola Okuphelele	≤0.30%
Ukungcola Okukodwa Okukhulu	≤0.10%
I-Enantiomer	≤0.20%
Izincibilikisi Ezisele
I-Methanol	≤0.30%
I-Dichloromethane	≤0.06%
n-Hexane	≤0.029%
I-Tetrahydrofuran	≤0.072%
I-N, N-Dimethylformamide	≤0.088%
I-Toluene	≤0.089%
Okuqukethwe Amanzi	5.8%~6.5%
Izinsalela ekushiseni	≤0.10%
Izinsimbi Ezisindayo	≤20ppm
Isivivinyo	98.0%~102.0% (C12H15N5O3 ibalwa ngesisekelo se-anhydrous)
Usayizi Wezinhlayiyana	I-D90: ≤100µm
Izinga Lokuhlola	I-Enterprise Standard
Ukusetshenziswa	I-API, isidakamizwa esilwa namagciwane esisetshenziswa ekwelapheni i-Hepatitis B Infection

Iphakheji nesitoreji:

Iphakheji: Ibhodlela, isikhwama se-Aluminium foil, isigubhu seCardboard, 25kg/Drum, noma ngokwezidingo zekhasimende.

Isimo Sesitoreji:Gcina ezitsheni ezivaliwe endaweni epholile neyomile;Vikela ekukhanyeni, umswakama kanye nezinambuzane.

Izinzuzo:

I-FAQ:

Isicelo:

I-Entecavir isizukulwane esisha se-guanine nucleoside analogues imithi yomlomo yokwelashwa kwe-Hepatitis B Virus (HBV) ukutheleleka, ikakhulukazi ekwelapheni iziguli ezikhulile ezinomsebenzi wokuphindaphinda kwegciwane kanye ne-serum transaminase yaqhubeka nokukhula, noma izicubu zesibindi zomsebenzi we-pathological we-hepatitis B engapheli. , okwamanje igciwane eliphansi lishesha kakhulu futhi linamandla kakhulu, izinga lokuguqulwa kwama-nucleoside analogue eliphansi kakhulu.Idatha ibonisa ukuthi okuhlukile ezigulini ezine-hepatitis B engapheli, kuhlanganise ne-nucleoside naive kanye ne-nucleoside ephathwayo kanye neziguli ze-cirrhosis yesibindi, ukusebenzisa amaphilisi e-entecavir kahle ekwelapheni kungalawula lesi sifo ngokushesha futhi kufinyelele kalula ukwelashwa kokuphela kweqiniso, okuyigciwane le-hepatitis B elingenakulinganiswa;ngokubambelela ekwelashweni, ingxenye enkulu yeziguli ingafika ekupheleni kokwaneliseka kokwelashwa, okungukuthi ukuguqulwa kwe-antigen serology, ezinye iziguli zingakwazi ngisho nokufinyelela ekahle yokwelashwa kokuphela, okungukuthi i-surface antigen negative.