I-Epalrestat CAS 82159-09-9 Purity >99.5% (HPLC) Factory
I-Shanghai Ruifu Chemical Co., Ltd. ingumkhiqizi ohamba phambili we-Epalrestat (CAS: 82159-09-9) enekhwalithi ephezulu.I-Ruifu Chemical ingahlinzeka ngokulethwa komhlaba wonke, amanani ancintisanayo, amanani amancane nayinqwaba atholakalayo.Thenga i-Epalrestat,Please contact: alvin@ruifuchem.com
| Igama Lekhemikhali | Epalrestat |
| Omqondofana | Epalrest;I-ONO-2235;U-Eabeth;Kinedak;I-Sorbistat;(5Z)-5-[(2E)-2-Methyl-3-phenyl-2-propen-1-ylidene]-4-oxo-2-thioxo-3-Thiazolidineacetic Acid;2--[(5Z)-5-[(E)-3-Phenyl-2-methylprop-2-enylidene]- 4-oxo-2-thioxo-3-thiazolidinyl]acetic Acid;(E,E) -2-[5-(2-Methyl-3-phenyl-prop-2-enylidene)-4-oxo-2-sulfanylidene-thiazolidin-3-yl]acetic Acid |
| Isimo Sesitoko | In Stock, Mass Production |
| Inombolo ye-CAS | 82159-09-9 |
| I-Molecular Formula | I-C15H13NO3S2 |
| Isisindo samangqamuzana | 319.39 g/mol |
| I-Melting Point | 222.0 ukuze 226.0 ℃ |
| Ukuminyana | 1.43±0.10 g/cm3 |
| Ukuncibilika | I-DMSO 2 mg/mL Amanzi <1 mg/mL I-Ethanol <1 mg/mL |
| Isikhathi Sokugcina. | Indawo Epholile Neyomile (-20℃) |
| I-COA ne-MSDS | Iyatholakala |
| Isigaba | I-API |
| Ibhrendi | I-Ruifu Chemical |
| Izinto | Amazinga Wokuhlola | Imiphumela |
| Ukubukeka | I-Orenji ukuya ku-Orenji I-Crystalline Powder Ebomvu | Iyahambisana |
| Ukuhlonza | Ifana nesikhathi sokugcina se-HPLC esijwayelekile | Dlula |
| I-Melting Point | 222.0 ukuze 226.0 ℃ | 222.4~224.3℃ |
| Ukulahlekelwa Ekumisweni | <0.50% | 0.04% |
| Izinsalela ekushiseni | <0.20% | 0.03% |
| Izinsimbi Ezisindayo (Pb) | ≤20ppm | <20ppm |
| Ukungcola Okuphelele | ≤0.50% | 0.20% |
| Ukuhlanzeka / Indlela Yokuhlaziya | >99.5% (HPLC) | 99.8% |
| I-Infrared Spectrum | Ivumelana Nesakhiwo | Iyahambisana |
| Isiphetho | Umkhiqizo uhloliwe futhi uthobelana nemibandela enikeziwe | |
Iphakheji:Ibhodlela, isikhwama se-Aluminium foil, 25kg/Cardboard Drum, noma ngokwezidingo zekhasimende.
Isimo Sesitoreji:Gcina ezitsheni ezivaliwe endaweni epholile futhi eyomile (-20℃) kude nezinto ezingahambelani.Vikela ekukhanyeni nakumswakama.
Ukuthumela:Thumela emhlabeni wonke nge-FedEx / DHL Express.Nikeza ukulethwa okusheshayo nokuthembekile.
Indlela Yokuthenga?Sicela uxhumaneDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
Iminyaka engu-15 Yokuhlangenwe nakho?Sinesipiliyoni seminyaka engaphezu kwe-15 ekwakhiweni nasekuthumeleni kwamanye amazwe uhla olubanzi lwezinga eliphezulu lokuxhumanisa imithi noma amakhemikhali amahle.
Izimakethe Eziyinhloko?Thengisa emakethe yasekhaya, eNyakatho Melika, eYurophu, eNdiya, eKorea, eJapane, e-Australia, njll.
Izinzuzo?Ikhwalithi ephezulu, intengo ethengekayo, izinsizakalo ezichwepheshile nokusekelwa kobuchwepheshe, ukulethwa okusheshayo.
IkhwalithiIsiqiniseko?Isistimu yokulawula ikhwalithi eqinile.Imishini yobuchwepheshe yokuhlaziya ifaka i-NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, NOMA, KF, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, njll.
Amasampula?Imikhiqizo eminingi inikeza amasampula wamahhala wokuhlolwa kwekhwalithi, izindleko zokuthumela kufanele zikhokhelwe amakhasimende.
Ukuhlolwa Kwemboni?Wamukelekile ekucwaningweni kwemboni.Sicela wenze i-aphoyintimenti kusengaphambili.
I-MOQ?Ayikho i-MOQ.I-oda elincane liyamukeleka.
Isikhathi sokuthumela? Uma kungaphakathi kwesitoko, ukulethwa kwezinsuku ezintathu kuqinisekisiwe.
Ezokuthutha?By Express (FedEx, DHL), by Air, by Sea.
Amadokhumenti?Ngemuva kwenkonzo yokuthengisa: I-COA, i-MOA, i-ROS, i-MSDS, njll.
Custom Synthesis?Ingahlinzeka ngezinsizakalo zokwenziwa ngokwezifiso ukuze zilingane kangcono nezidingo zakho zocwaningo.
Imigomo Yokukhokha?I-invoyisi ye-Proforma izothunyelwa kuqala ngemva kokuqinisekiswa kwe-oda, kufakwe nemininingwane yethu yasebhange.Inkokhelo nge-T/T (Telex Transfer), PayPal, Western Union, njll.
Ama-ID we-UN 2811
I-WGK Germany 3
I-RTECS XJ5131855
I-Hazard Class 6.1
Ukupakisha Iqembu II
I-Epalrestat (CAS: 82159-09-9) iyi-aldose reductase inhibitor yesibili ezokwethulwa emhlabeni wonke futhi eyokuqala yethulwa e-Japan.I-Epalrestat iboniswa ekwelapheni i-neuropathy yesifo sikashukela.Kuyaphenywa futhi nge-retinopathy yesifo sikashukela kanye ne-nephropathy.I-Epalrestat iyi-aldose reductase inhibitor ene-IC50 yama-72 nM.
I-Epalrestat inhibits i-Aldose Reductase (AR) ehilelekile esinyathelweni somkhawulo wezinga ekuguquleni i-glucose ibe yi-sorbitol ngaphansi kwezimo ze-hyperglycemic.I-Aldose reductase bekuyimpoqo yabaphenyi abaningi bemitholampilo ukuze belaphe i-neuropathy yesifo sikashukela kanye ne-retinopathy.I-Epalrestat iyisidakamizwa esivunyiwe e-Japan nase-India, esisetshenziselwa ukwelapha i-neuropathy yesifo sikashukela.
I-Epalrestat isetshenziselwa ukuvimbela, ukuthambisa, nokwelapha i-peripheral neuropathy (ukuba ndikindiki, ubuhlungu), i-vibrational paresthesia, kanye nokungajwayelekile kwenhliziyo okuhambisana nesifo sikashukela.
I-Epalrestat njengomuthi wayo omele inciphisa ukuqoqwa kwe-intracellular ye-fructose ne-sorbitol ngokuvimbela ngokuphindiselayo umsebenzi we-aldose reductase, ibuyisela umsebenzi we-Na+-K+-ATPase kanye ne-inositol, ikhuphule ukwakheka KOKUNGEKHO kumaseli e-endothelial, ivimbele indlela yokubonisa i-protein kinase C, i-endothelial cell-adhesion. i-mediated neutrophil kanye ne-endothelial adhesion factor expression futhi kunciphisa imikhiqizo ye-carboxymethyl lysine ezigulini ezinesifo sikashukela, ngaleyo ndlela zelaphe izifo ezifana nesifo sikashukela kanye nezinkinga zaso.
