I-Ethyl (S)-4-Chloro-3-hydroxybutyrate CAS 86728-85-0 Isithombe Esifakiwe Se-Atorvastatin Calcium Esimaphakathi

I-Ethyl (S)-4-Chloro-3-hydroxybutyrate CAS 86728-85-0 Atorvastatin Calcium Intermediate

Incazelo emfushane:

Igama Lekhemikhali: I-Ethyl (S)-4-Chloro-3-hydroxybutyrate

I-CAS: 86728-85-0

Ukubukeka: Uketshezi Olungenambala ukuya Kuphuzi Oluphuzi

Ubumsulwa: ≥98.0% (GC)

Okumaphakathi kwe-Atorvastatin Calcium (CAS: 134523-03-8)

Inquiry: alvin@ruifuchem.com

Thumela i-imeyili kithi

Imininingwane Yomkhiqizo

Imikhiqizo Ehlobene

Omaka bomkhiqizo

Incazelo:

Chemical Properties:

Igama Lekhemikhali	I-Ethyl (S) -4-Chloro-3-hydroxybutyrate
Omqondofana	(S)-4-Chloro-3-hydroxybutyric Acid Ethyl Ester
Inombolo ye-CAS	86728-85-0
Inombolo yeCAT	I-RF-PI139
Isimo Sesitoko	Esitokweni, Isikali Sokukhiqiza Sifinyelela Kumathani
I-Molecular Formula	I-C6H11ClO3
Isisindo samangqamuzana	166.6
Ukuminyana	1.19 g/mL ku-25℃ (lit.)
I-Refractive Index	n20/D 1.453 (lit.)
Ibhrendi	I-Ruifu Chemical

Imininingwane:

Into	Imininingwane
Ukubukeka	Uketshezi Olungenambala Kuya Kuphuzi Okuphuzi
Ukuhlanzeka / Indlela Yokuhlaziya	≥98.0% (GC)
Umswakama (KF)	≤0.50%
I-Ethyl-4-Chloro Aceto Acetate	≤0.50%
Izinga Lokuhlola	I-Enterprise Standard
Ukusetshenziswa	Pharmaceutical Intermediate;I-Organic Synthesis

I-Ethyl (S)-4-Chloro-3-hydroxybutyrate (CAS: 86728-85-0)
Indlela yokuhlaziya
Incazelo
Thatha cishe isampula ye-10ml epuleti lengilazi elihlanzekile nelomile bese uhlola.
Ukuzungezisa okuqondile
Dlulisa ngokunembile mayelana ne-1.0g yesampula ku-100ml ye-volumetric flask futhi incibilike10 ml we-chloroform, bese uhlanza nge-chloroform ku-100ml bese uxuba.
Linganisa ukujikeleza kokubona kwesampula yokuhlola ku-25ºC naku-589nm wavelengthbala ukuzungezisa okuqondile ngokwefomula enikeziwe.
[α]25D = (v×a)/[w×(1-b)]
[α]25D: ukuzungezisa okuthile kokuhlolwaisampula;α: ukuzungezisa okubonwayoi-angular degree;w: isisindo sesampula (g);
v: umthamo (mL);
b: Okuqukethwe kwamanzi(%)
Purity (by GC)
Izimo zeChromatographic: I-Gas chromatography ifakwe ilangabiumtshina we-ionization
Ikholomu: SE-54, 30m×0.35mm×0.25µm
Izinga lokushisa likahhavini: Izinga lokushisa lokuqala ngu-120 ℃, Bamba isikhathi se-2min
Irempu: 20℃/min
Izinga lokushisa: 250 ℃, Bamba isikhathi 2min
Izinga lokushisa lomjovo: 250 ℃
Izinga lokushisa lomtshina: 250 ℃(FID)
Ivolumu yomjovo: 0.2µl
Isixazululo sesampula: nciphisa i-1ml A4 nge-1ml acetone.
Inqubo: Jova u-0.2µl we-acetone njengengenalutho futhi urekhode i-chromatogram.KweI-chromatogram etholwe ku-diluent akufanele kube khona ukuphazamiseka ku-isikhathi sokugcina sesiqongo esikhulu nesiqongo sokungcola.Kunokujova isisombululo sesampulaphindaphinda ku-chromatograph futhi urekhode i-chromatogram.Bika Ubumsulwa beisampula ngendlela yokujwayela kwendawo.

Iphakheji nesitoreji:

Iphakheji: Ibhodlela, Umgqomo, 25kg/Umgqomo, noma ngokwezidingo zekhasimende.

Isimo Sesitoreji:Gcina ezitsheni ezivaliwe endaweni epholile neyomile;Vikela ekukhanyeni, umswakama kanye nezinambuzane.

Izinzuzo:

I-FAQ:

Isicelo:

I-Shanghai Ruifu Chemical Co., Ltd. ingumkhiqizi oholayo nomphakeli we-Ethyl (S)-4-Chloro-3-hydroxybutyrate (CAS: 86728-85-0) enekhwalithi ephezulu, imaphakathi ngokuvamile ekuhlanganisweni kwe-Atorvastatin. I-calcium (i-CAS: 134523-03-8).

I-Atorvastatin Calcium (CAS: 134523-03-8) [igama lokuhweba: I-Lipitor] ikhonjiswe kakhulu ekwelapheni isifo senhliziyo nemithambo yegazi kanye ne-dyslipidemia ngenxa yomphumela wayo ekwehliseni i-cholesterol egazini.I-Atorvastatin isebenza ngokuyinhloko esibindini.Ukwehliswa kwamazinga e-cholesterol esibindini kwandisa ukumuncwa kwe-cholesterol esibindini futhi kunciphisa amazinga e-cholesterol e-plasma.I-Lipitor, kusukela ngo-1996, isibe umuthi othengwa kakhulu emhlabeni kuze kube yileso sikhathi.