I-Fingolimod Hydrochloride CAS 162359-56-0 Purity ≥99.0% (HPLC) API Factory High Purity
Umkhiqizi onokuhlanzeka Okuphezulu kanye Nekhwalithi Ezinzile
Igama Lekhemikhali: Fingolimod Hydrochloride
I-CAS: 162359-56-0
I-Fingolimod Hydrochloride umuthi ogunyazwe yi-FDA wokwelashwa kwe-Multiple Sclerosis.
Ikhwalithi ephezulu ye-API, Ukukhiqiza Kwezentengiso
Igama Lekhemikhali | I-Fingolimod Hydrochloride |
Omqondofana | I-Fingolimod HCl;FTY 720 |
Inombolo ye-CAS | 162359-56-0 |
Inombolo yeCAT | I-RF-API39 |
Isimo Sesitoko | Esitokweni, Isikali Sokukhiqiza Sifika Emakhulwini Amakhilogremu |
I-Molecular Formula | I-C19H34ClNO2 |
Isisindo samangqamuzana | 343.93 |
I-Melting Point | 102.0~107.0°C |
Ibhrendi | I-Ruifu Chemical |
Into | Imininingwane |
Ukubukeka | Impushana Emhlophe Kuya Kumhlophe |
Ukuhlonza | I-HPLC |
I-Melting Point | 102.0~106.0℃ |
Ukuncibilika | Incibilika Ngokuphelele Emanzini |
Ukuhlanzeka / Indlela Yokuhlaziya | ≥99.0% (HPLC) |
Umswakama (KF) | ≤0.50% |
Izinsalela ekushiseni | ≤0.20% |
Izinsimbi Ezisindayo | ≤20ppm |
Izincibilikisi Ezisele | |
I-Dichloromethane | ≤0.05% |
I-Ethyl Acetate | ≤0.50% |
I-Ethanol | ≤0.50% |
I-Methanol | ≤0.30% |
I-Toluene | ≤0.089% |
I-THF | ≤0.50% |
I-DMF | ≤0.088% |
Izinto Ezihlobene | |
Ukungcola Okukodwa | ≤0.50% |
Ukungcola Okuphelele | ≤1.0% |
Izinga Lokuhlola | I-Enterprise Standard |
Ukusetshenziswa | I-Active Pharmaceutical Ingredient (API) |
Iphakheji: Ibhodlela, isikhwama se-Aluminium foil, isigubhu seCardboard, 25kg/Drum, noma ngokwezidingo zekhasimende.
Isimo Sesitoreji:Gcina ezitsheni ezivaliwe endaweni epholile neyomile;Vikela ekukhanyeni, umswakama kanye nezinambuzane.
I-Shanghai Ruifu Chemical Co., Ltd. ingumkhiqizi oholayo nomphakeli we-Fingolimod Hydrochloride (CAS: 162359-56-0) enekhwalithi ephezulu.
I-Fingolimod Hydrochloride umuthi wokuqala womlomo wokwelapha i-multiple sclerosis.Ithuthukiswe ngempumelelo yinkampani eyenza imithi i-Novartis, futhi ivunyelwe ukumakethwa yi-US Food and Drug Administration (FDA).I-Multiple sclerosis yisifo sezinzwa esithena amandla esingabangela isiguli ukuba silahlekelwe umqondo wokulinganisela, kuvele ama-muscle spasms nokunye ukuphazamiseka kokunyakaza.I-Fingolimod Hydrochloride iyimoduli yokwamukela i-sphingosine-l-phosphate (S1PR).Ngemuva kwe-phosphorylation, Iboshelwe ku-s1P receptor engaphezulu kwe-lymphocyte, ezoshintsha ukufuduka kwe-lymphocyte, futhi ikhuthaze amaseli kuzicubu ze-lymphatic, futhi ivimbele ama-lymphocyte ekuphumeni kwezicubu ze-lymphoid futhi angene ku-graft.Ngaleyo ndlela, izovimbela la maseli ukuthi angangeni ohlelweni lwezinzwa oluphakathi (CNS), olufeza umphumela wokuzivikela komzimba.