I-Gliepiride CAS 93479-97-1 Assay 98.0%~102.0% Isithombe Esifakiwe Sefekthri ye-API Ehlanzekile Ephakeme

I-Gliepiride CAS 93479-97-1 Assay 98.0%~102.0% API Factory High Purity

Incazelo emfushane:

Igama Lekhemikhali: Glimepiride

I-CAS: 93479-97-1

Ukubukeka: Impushana Emhlophe noma Cishe Emhlophe

Isilinganiso: 98.0%~102.0%

I-Gliepiride ekwelapheni Isifo sikashukela sohlobo 2 esingancike ku-insulin

Ikhwalithi ephezulu ye-API, Ukukhiqiza Kwezentengiso

Inquiry: alvin@ruifuchem.com

Thumela i-imeyili kithi

Imininingwane Yomkhiqizo

Imikhiqizo Ehlobene

Omaka bomkhiqizo

Incazelo:

Nikeza Ngokuhlanzeka Okuphezulu kanye Nekhwalithi Ezinzile
Igama Lekhemikhali: Glimepiride
I-CAS: 93479-97-1
I-Gliepiride ekwelapheni Isifo sikashukela sohlobo 2 esingancike ku-insulin
Ikhwalithi ephezulu ye-API, Ukukhiqiza Kwezentengiso

Chemical Properties:

Igama Lekhemikhali	I-Glimepiride
Omqondofana	Amaril
Inombolo ye-CAS	93479-97-1
Inombolo yeCAT	I-RF-API24
Isimo Sesitoko	Esitokweni, Isikali Sokukhiqiza Sifinyelela Kumathani
I-Molecular Formula	I-C24H34N4O5S
Isisindo samangqamuzana	490.62
I-Melting Point	212.2 ~ 214.5℃
Isimo Sokuthumela	Ngaphansi Kwezinga Lokushisa Le-Ambient
Ibhrendi	I-Ruifu Chemical

Imininingwane:

Into	Imininingwane
Ukubukeka	Impushana Emhlophe noma Ecishe Emhlophe
Ukuhlonza	I-IR (Ifana Nejwayelekile)
Izinto Ezihlobene
I-Cis-Isomer (A)	≤0.80%
I-Sulfonamide (B)	≤0.40%
I-urethane (C)	≤0.10%
3-Isomer (D)	≤0.20%
Noma Ikuphi Okunye Ukungcola	≤0.10%
Ukungcola Okuphelele	≤0.50%
Ukulahlekelwa Ekumisweni	≤0.50%
Izinsalela ekushiseni	≤0.10%
Izinsimbi Ezisindayo	≤0.001%
Isivivinyo	98.0%~102.0%
Izinga Lokuhlola	I-European Pharmacopeia (EP);I-United States Pharmacopoeia (USP)
Ukusetshenziswa	I-Active Pharmaceutical Ingredient (API)

Iphakheji nesitoreji:

Iphakheji: Ibhodlela, isikhwama se-Aluminium foil, isigubhu seCardboard, 25kg/Drum, noma ngokwezidingo zekhasimende.

Isimo Sesitoreji:Gcina ezitsheni ezivaliwe endaweni epholile neyomile;Vikela ekukhanyeni, umswakama kanye nezinambuzane.

Izinzuzo:

I-FAQ:

Isicelo:

I-Shanghai Ruifu Chemical Co., Ltd. ingumkhiqizi oholayo nomnikezeli we-Gliepiride (CAS: 93479-97-1) enekhwalithi ephezulu, isithako esisebenzayo semithi (API).I-Glimipiride iyisidakamizwa se-antidiabetic esiza ukulawula amazinga kashukela egazini.I-Glimepiride iyi-sulfonylurea yesizukulwane sesithathu esebenza isikhathi eside enomsebenzi we-hypoglycemic.

I-Glimepiride (igama lokuhweba lokuqala i-Amaryl) isidakamizwa esilwa ne-sulfonylurea esisebenzayo esitholakala ngomlomo kuya kwesikhathi eside.Njengawo wonke ama-sulfonylureas, i-glimepiride isebenza njenge-secretagogue ye-insulin.Yehlisa ushukela wegazi ngokukhuthaza ukukhululwa kwe-insulin kumaseli e-beta asebenzayo kanye nokwandisa ukuzwela kwezicubu ezijikelezayo ku-insulin.I-Gliepiride kungenzeka ibophezele kuma-receptors e-potassium ezwela ku-ATP endaweni yeseli le-pancreatic, inciphise ukuqhutshwa kwe-potassium futhi ibangele ukuwohloka kwe-membrane.I-Membrane depolarization ikhuthaza ukungena kwe-calcium ion ngamashaneli e-calcium azwela amandla kagesi.Lokhu kwanda kokuhlushwa kwe-calcium ion ye-intracellular kudala ukukhiqizwa kwe-insulin.I-Gliepiride isetshenziswa kakhulu ekwelapheni iziguli ezinesifo sikashukela sohlobo 2 futhi inganciphisa namathuba okuthi umuntu abe nezinkinga zohlobo 2 lwesifo sikashukela.Umuthi wagunyazwa yi-FDA ngo-1995 futhi ukhiqizwa ngabakwaSanofi-Aventis.Ingasetshenziswa kanye nohlelo olufanele lokudla kanye nokuzivocavoca futhi ingase isetshenziswe iyodwa noma neminye imithi ye-antidiabetic uma kudingeka.I-Glimepiride ingasetshenziswa njenge-monotherapy noma ihlanganiswe ne-insulin.