I-HBTU CAS 94790-37-1 Peptide Coupling Reagent Purity >99.0% (HPLC) Factory
I-Shanghai Ruifu Chemical Co., Ltd. ingumkhiqizi ohamba phambili we-HBTU (CAS: 94790-37-1) enekhwalithi ephezulu.I-Ruifu Chemical ihlinzeka ngochungechunge lwama-reagents avikelayo kanye nama-reagents ahlanganisayo.I-Ruifu inganikeza ukulethwa komhlaba wonke, intengo encintisanayo, amanani amancane nayinqwaba atholakalayo.Thenga i-HBTU,Please contact: alvin@ruifuchem.com
Igama Lekhemikhali | I-HBTU |
Omqondofana | 1--[Bis (dimethylamino) methylene] -1H-benzotriazolium 3-Oxide Hexafluorophosphate;N,N,N′,N′-Tetramethyl-O-(1H-Benzotriazol-1-yl)uronium Hexafluorophosphate;I-O-Benzotriazole-N,N,N',N'-Tetramethyluronium-Hexafluorophosphate;O-(1H-Benzotriazol-1-yl)-N,N,N',N'-Tetramethyluronium Hexafluorophosphate;2-(1H-Benzotriazole-1-yl)-1,1,3,3-Tetramethyluronium Hexafluorophosphate |
Isimo Sesitoko | Esitokweni, Isikali Sokuhweba |
Inombolo ye-CAS | 94790-37-1 |
I-Molecular Formula | I-C11H16F6N5OP |
Isisindo samangqamuzana | 379.25 g/mol |
I-Melting Point | ≥200℃ |
Ukuminyana | 1.5095 |
Kuyazwela | Izwela Ukukhanya, Izwela Umswakama |
Ukuncibilika kwamanzi | Ayincibiliki Emanzini |
Ukuncibilika | Incibilika ku-Acetonitrile.Incibilika Kancane ku-acetone, i-Ethanol |
Isikhathi Sokugcina. | Indawo epholile neyomile (2~8℃) |
I-COA ne-MSDS | Iyatholakala |
Isigaba | Ama-Reagents wokuhlanganisa |
Ibhrendi | I-Ruifu Chemical |
Izinto | Amazinga Wokuhlola | Imiphumela |
Ukubukeka | I-Crystalline Powder Emhlophe | Iyahambisana |
I-Melting Point | ≥200℃ | 205.6℃ |
Ukulahlekelwa Ekumisweni | <0.50% | 0.11% |
Ukuhlanzeka / Indlela Yokuhlaziya | >99.0% (HPLC) | 99.9% |
I-Infrared Spectrum | Ivumelana Nesakhiwo | Iyahambisana |
I-NMR Spectrum 1H | Ivumelana Nesakhiwo | Iyahambisana |
I-Fluorine NMR Spectrum | Ivumelana Nesakhiwo | Iyahambisana |
Ukuhlolwa kwe-Solubility ku-Acetonitrile | 1g ku-10ml i-Acetonitrile Clear Solution | Dlula |
Isiphetho | Umkhiqizo uhloliwe futhi uthobelana nezicaciso |
Iphakheji:Ibhodlela, isikhwama se-Aluminium foil, 25kg/Cardboard Drum, noma ngokwezidingo zekhasimende.
Isimo Sesitoreji:Gcina ezitsheni ezivaliwe endaweni epholile neyomile (2~8℃) kude nezinto ezingahambelani.Vikela ekukhanyeni nakumswakama.
Ukuthumela:Thumela emhlabeni wonke nge-FedEx / DHL Express.Nikeza ukulethwa okusheshayo nokuthembekile.
1. Izakhiwo: Lo mkhiqizo kufanele ube yimpushana ecwebezelayo emhlophe.
2. Ukunqunywa kokuqukethwe: ngokuya ngokusebenza okuphezulu kwe-chromatography yoketshezi (i-Chinese Pharmacopoeia 2010 edition Appendix VI D).
Izimo ze-Chromatographic: Ijeli ye-silica ehlanganisiwe ye-octadecylsilane yasetshenziswa njengokugcwalisa, (250*4.6mm*5.0μm);I-Acetonitrile: amanzi =15:85 (i-pH ilungiswe yi-acetic acid =2.5) njengesigaba seselula;Ubude bokutholwa bebungu-258nm.Izinga lokugeleza: 0.5ml / min;Inani lamapuleti etiyetha ngokwe-HBTU
Inani eliphakeme kakhulu kufanele libalwe lingabi ngaphansi kuka-2000.
Indlela yokunquma: Thatha inani elifanele lalo mkhiqizo, yenza isisombululo sesigaba seselula esiqukethe i-HBTU 20μg nge-1ml ngayinye, njengesixazululo sokuhlola.I-10 μL yesisombululo sokuhlola ijovwe ku-chromatograph futhi isikhathi sokugcinwa kwenani eliyinhloko lengxenye eyinhloko sarekhodwa.
Imiphumela: Ngokwendlela yokujwayelekile yendawo, okuqukethwe kwe-HBTU akufanele kube ngaphansi kuka-99.0%.
3. Iphuzu elincibilikayo: ngokwendlela yokunquma indawo encibilikayo (Isithasiselo VIIC sohlelo lwe-Chinese Pharmacopoeia 2010), izinga lokushisa ngu-3℃/min.
Indawo yokuncibilika yalo mkhiqizo ayikho ngaphansi kuka-200.0 ℃.
4. Ukulahlekelwa ekumisweni: thatha lo mkhiqizo ku-80 ℃ futhi wome ngaphansi kwengcindezi encishisiwe amahora angu-4 kuya kwesisindo esiqhubekayo, futhi ukulahlekelwa kwesisindo akufanele kudlule u-0.50%.
5. Ukucaciswa kwesixazululo: thatha i-1g yalo mkhiqizo, engeza i-10ml ye-acetonitrile, unyakazise kahle, isisombululo kufanele sicace futhi sibonakale.
6. Isitoreji: Gcina endaweni emnyama nepholile eyomile (2~8℃).
7. Isikhathi sokubukeza: unyaka owodwa.
Indlela Yokuthenga?Sicela uxhumaneDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
Iminyaka engu-15 Yokuhlangenwe nakho?Sinesipiliyoni seminyaka engaphezu kwe-15 ekwakhiweni nasekuthumeleni kwamanye amazwe uhla olubanzi lwezinga eliphezulu lokuxhumanisa imithi noma amakhemikhali amahle.
Izimakethe Eziyinhloko?Thengisa emakethe yasekhaya, eNyakatho Melika, eYurophu, eNdiya, eKorea, eJapane, e-Australia, njll.
Izinzuzo?Ikhwalithi ephezulu, intengo ethengekayo, izinsizakalo ezichwepheshile nokusekelwa kobuchwepheshe, ukulethwa okusheshayo.
IkhwalithiIsiqiniseko?Isistimu yokulawula ikhwalithi eqinile.Imishini yobuchwepheshe yokuhlaziya ifaka i-NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, NOMA, KF, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, njll.
Amasampula?Imikhiqizo eminingi inikeza amasampula wamahhala wokuhlolwa kwekhwalithi, izindleko zokuthumela kufanele zikhokhelwe amakhasimende.
Ukuhlolwa Kwemboni?Wamukelekile ekucwaningweni kwemboni.Sicela wenze i-aphoyintimenti kusengaphambili.
I-MOQ?Ayikho i-MOQ.I-oda elincane liyamukeleka.
Isikhathi sokuthumela? Uma kungaphakathi kwesitoko, ukulethwa kwezinsuku ezintathu kuqinisekisiwe.
Ezokuthutha?By Express (FedEx, DHL), by Air, by Sea.
Amadokhumenti?Ngemuva kwenkonzo yokuthengisa: I-COA, i-MOA, i-ROS, i-MSDS, njll.
Custom Synthesis?Ingahlinzeka ngezinsizakalo zokwenziwa ngokwezifiso ukuze zilingane kangcono nezidingo zakho zocwaningo.
Imigomo Yokukhokha?I-invoyisi ye-Proforma izothunyelwa kuqala ngemva kokuqinisekiswa kwe-oda, kufakwe nemininingwane yethu yasebhange.Inkokhelo nge-T/T (Telex Transfer), PayPal, Western Union, njll.
Amakhodi Engozi
R36/37/38 - Ukucasula amehlo, uhlelo lokuphefumula kanye nesikhumba.
R20/21/22 - Kuyingozi ngokuhogela, ukuthintana nesikhumba futhi uma ukugwinyile.
R42/43 - Ingabangela ukuzwela ngokuhogela umoya nangokuthinta isikhumba.
Incazelo Yokuphepha
S26 - Uma uthintana namehlo, geza ngokushesha ngamanzi amaningi futhi ufune iseluleko sezokwelapha.
I-S36/37/39 - Gqoka izingubo zokuzivikela ezifanele, amagilavu nokuvikela iso/ubuso.
I-S36 - Gqoka izingubo ezifanele zokuzivikela.
S22 - Ungaphefumuli uthuli.
I-WGK Germany 3
I-FLUKA BRAND F AMAKHODI 8-10-21
I-HS Code 2933990099
I-Hazard Note Irritant
Ubuthi LD50 ngomlomo kuNogwaja: > 2000 mg/kg
I-HBTU (CAS: 94790-37-1) i-reagent yokuhlanganisa esetshenziswa ekuhlanganiseni kwe-peptide.I-HBTU ikhonjiswe ukuthi icindezela ngempumelelo i-racemization.
I-HBTU iyi-reagent yokuhlanganisa evame ukusetshenziswa ekuhlanganiseni kwesigaba esiqinile se-peptide synthesis.I-HBTU iphinde yasetshenziswa kuphrothokholi ejwayelekile ye-Fmoc-based solid-phase peptide synthesis (SPPS).
I-HBTU, ngemva kokwethulwa ngo-1978, i-ejenti ye-HBTU ikhombisa ukuduma kumakhemikhali nokusetshenziswa kwemboni ngenxa yezakhiwo zayo ezisebenzayo ezithambile.ngaphezu kwalokho, iphinde ikhombise ukumelana ne-racemization.ukuthambekela okuphansi kwe-racemization kuyisidingo esibalulekile sokuhlanganiswa kwe-peptide.ikakhulukazi ekuhlanganiseni kwe-peptide yesigaba esiqinile, izivuno zobuningi ezinezikhathi ezimfushane zokusabela zibalulekile ukuze kwenziwe ukuhlanganiswa kwama-peptide amakhulu kwenzeke.
Ucwaningo lwakamuva lubonisa ukuthi i-crystal kanye nesakhiwo sesisombululo salesi senzo sokuhlanganisa siyi-guanidinium N-oxide hhayi inhlanganisela ye-uronium;I-coupling reagent ye-peptide synthesis;izinzuzo yilezi: i-racemization ephansi kakhulu, izimo zokusabela ezilula, isikhathi esifushane kakhulu sokusabela, kanye nesivuno esiphezulu.
I-Peptide synthesis incike kakhulu kuma-reagents asebenza kahle futhi aphephile.I-HBTU yafakazelwa ukuthi iguqula ama-carboxylic acid abe ama-azides ngendlela ephumelelayo futhi engokoqobo.inqubo ingase isetshenziswe ezinhlobonhlobo eziningi ze-carboxylic acid kuhlanganise nama-amino acid avikelwe ngu-n.ngaphezu kwalokho, i-HBTU yayinenani elikhulu ekuhlanganiseni kwebhodwe elilodwa le-dipeptidyl urea esters, ureas, nama-carbamates avela kuma-acids.izinzuzo ze-HBTU zazihlanganisa amaphuzu alandelayo: 1) aziqhumi ngakho-ke zifaneleka kakhulu ukuhlanganiswa kwe-peptide yesisombululo/esiqinile.2) i-solubility ephezulu nokuzinza kuma-solvents classical.3) kungenzeka ukuqapha ukusabela kwe-colorimetric.