I-Ibrutinib Deacryloylpiperidine CAS 330786-24-8 Ubumsulwa >99.0% (HPLC)

Incazelo emfushane:

Igama Lekhemikhali: Ibrutinib Deacryloylpiperidine

I-CAS: 330786-24-8

Ubumsulwa: >99.0% (HPLC)

Ukubukeka: Okumhlophe-Kumhlophe ukuya kuPhoda weKhaki

I-Ibrutinib emaphakathi (CAS: 936563-96-1)

Thintana: UDkt. Alvin Huang

Iselula/Wechat/WhatsApp: +86-15026746401

E-Mail: alvin@ruifuchem.com

Thumela i-imeyili kithi

Imininingwane Yomkhiqizo

Imikhiqizo Ehlobene

Omaka bomkhiqizo

Incazelo:

Chemical Properties:

Igama Lekhemikhali	3-(4-Phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine
Omqondofana	I-Ibrutinib ephakathi kwe-N-2;Ibrutinib Deacryloylpiperidine;Ibrutinib Ukungcola 8;5-(4-Phenoxyphenyl) -7H-pyrrolo[2,3-d]pyrimidin-4-ylamine;I-IBT4A;Ibrutinib N-Despiperidinyl Ukungcola
Inombolo ye-CAS	330786-24-8
Isimo Sesitoko	Esitokweni, Isikali Sokukhiqiza Sifinyelela Kumathani
I-Molecular Formula	I-C17H13N5O
Isisindo samangqamuzana	303.32
I-Melting Point	>262℃(dec.)
Ukuminyana	1.380±0.06 g/cm3
I-Hazard Class	6.1;Ubuthi
Iqembu Lokupakisha	III
I-COA ne-MSDS	Iyatholakala
Umsuka	Shanghai, China
Ibhrendi	I-Ruifu Chemical

Imininingwane:

Into	Imininingwane
Ukubukeka	I-Off-White kuya ku-Khaki Powder
Ukuhlonza	HNMR, LC-MS
Ukuhlanzeka / Indlela Yokuhlaziya	>99.0% (HPLC)
Ukulahlekelwa Ekumisweni	<1.00%
I-Single Max.Ukungcola	<1.00%
Ukungcola Okuphelele	<1.00%
Izinsimbi Ezisindayo (njenge-Pb)	<20ppm
Izinga Lokuhlola	I-Enterprise Standard
Ukusetshenziswa	I-Ibrutinib emaphakathi (CAS: 936563-96-1)

Iphakheji nesitoreji:

Iphakheji: Ibhodlela, isikhwama se-Aluminium foil, 25kg/Cardboard Drum, noma ngokwezidingo zekhasimende.

Isimo Sesitoreji:Gcina ezitsheni ezivaliwe endaweni epholile neyomile;Vikela ekukhanyeni nakumswakama.

Izinzuzo:

I-FAQ:

330786-24-8 - Isicelo:

I-3-(4-Phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine (CAS: 330786-24-8) iyingxenye yokwenziwa ewusizo ekuhlanganiseni kwe-Ibrutinib (CAS: 936563-96-1 ).I-Ibrutinib iwuhlobo lwe-Bruton tyrosine kinase (BTK) inhibitor, ingasetshenziselwa ukwelapha i-lymphocytic leukemia (CLL) kanye ne-mantle cell lymphoma (MCL).I-MCL ne-CLL kungokwe-B-cell non-Hodgkin's lymphoma, okunzima ukuyelapha futhi kulula ukuphindeka ngayo.I-chemical immunotherapy evamile ayinakho ukukhomba, ngokuvamile kwenzeka 3 noma 4 ukusabela okubi.I-Ibrutinib ne-B lymphocyte ingakhomba nge-BTK edingekayo ekwakhekeni, ukuhlukaniswa, nokudluliselwa kolwazi, ivimbele umsebenzi we-BTK ngendlela engenakuhlehliswa, futhi ivimbele ukwanda kwamangqamuzana esimila kanye nokuphila ngempumelelo.I-Ibrutinib ingamuncwa ngokushesha ngemva kokuphathwa ngomlomo, ngesikhathi se-1 ~ 2h ifinyelele ekugxilweni okuphezulu kwegazi, ukusabela okungalungile kungokweyodwa noma ezimbili, ngakho-ke, i-Ibrutinib izoba ukukhetha okusha kokwelashwa kwe-CLL ne-MCL.