N-(2-Methyl-5-nitrophenyl)-4-(pyridin-3-yl)pyrimidin-2-amine CAS 152460-09-8 Imatinib Mesylate Intermediate High Purity
Ukunikezwa Kwezohwebo I-Imatinib Mesylate kanye Nezixhumanisi Ezihlobene:
I-Imatinib Mesylate CAS: 220127-57-1
N-(2-Methyl-5-nitrophenyl)-4-(pyridin-3-yl)pyrimidin-2-amine CAS: 152460-09-8
N-(5-Amino-2-methylphenyl)-4-(3-pyridyl)-2-pyrimidinea CAS: 152460-10-1
4--[(4-Methylpiperazin-1-yl)methyl]benzoic acid dihydrochloride CAS: 106261-49-8
Igama Lekhemikhali | N-(2-Methyl-5-nitrophenyl)-4-(pyridin-3-yl)pyrimidin-2-amine |
Omqondofana | I-Imatinib Mesylate Intermediate;2-(2-Methyl-5-nitroanilino)-4-(3-pyridyl)pyrimidine |
Inombolo ye-CAS | 152460-09-8 |
Inombolo yeCAT | I-RF-PI228 |
Isimo Sesitoko | Esitokweni, Isikali Sokukhiqiza Sifinyelela Kumathani |
I-Molecular Formula | I-C16H13N5O2 |
Isisindo samangqamuzana | 307.31 |
I-Melting Point | 188.0~193.0℃ |
Ibhrendi | I-Ruifu Chemical |
Into | Imininingwane |
Ukubukeka | Impushana Ephuzi noma Cishe Ephuzi |
Ubumsulwa | ≥98.0% (HPLC) |
Umswakama (KF) | ≤0.50% |
Ukungcola Okuphelele | ≤2.0% |
Ukungcola Okukodwa Okukhulu | ≤1.0% |
Izinsalela ekushiseni | ≤0.50% |
Izinsimbi Ezisindayo | ≤20ppm |
Izinga Lokuhlola | I-Enterprise Standard |
Ukusetshenziswa | Okumaphakathi kwe-Imatinib Mesylate (CAS: 220127-57-1) |
Iphakheji: Ibhodlela, isikhwama se-Aluminium foil, isigubhu seCardboard, 25kg/Drum, noma ngokwezidingo zekhasimende.
Isimo Sesitoreji:Gcina ezitsheni ezivaliwe endaweni epholile neyomile;Vikela ekukhanyeni, umswakama kanye nezinambuzane.
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I-Shanghai Ruifu Chemical Co., Ltd. ingumkhiqizi oholayo nomnikezeli we-N-(2-Methyl-5-nitrophenyl)-4-(pyridin-3-yl)pyrimidin-2-amine (CAS: 152460-09-8) ngekhwalithi ephezulu.Kuyinto ephakathi ngokuvamile ekuhlanganiseni kwe-Imatinib Mesylate (CAS: 220127-57-1).
I-Imatinib Mesylate iyingqamuzana encane evimbela i-c-Abl protein-tyrosine kinase, Iqonde kakhulu i-BCR-ABL, i-enzyme ehlotshaniswa ne-chronic myelogenous leukemia (CML) kanye nezinhlobo ezithile ze-acute lymphoblastic leukemia (YONKE).Umcimbi wokuthutha phakathi kwama-chromosome 9 kanye no-22 ukhiqiza i-chromosome yase-Philadelphia, ebese ikhiqiza iphrotheni ye-Bcr-Abl fusion enomsebenzi we-aberrant kinase okhuthaza ukwanda okusheshayo kwamaseli.I-Imatinib Mesylate ihlanganisa le kinase ebalulekile, imisa ukukhula okuhlobene ne-CML.I-Imatinib Mesylate iphinde yaboniswa ukuze ivimbele i-PDGFR kanye ne-tyrosine kinases ehlotshaniswa ne-c-Kit.Amafomula aqukethe i-Imatinib Mesylate asetshenziswe ekwelapheni umdlavuza ohlukahlukene.