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N-(2-Methyl-5-nitrophenyl)-4-(pyridin-3-yl)pyrimidin-2-amine CAS 152460-09-8 Imatinib Mesylate Intermediate High Purity Isithombe Esifakiwe
  • N-(2-Methyl-5-nitrophenyl)-4-(pyridin-3-yl)pyrimidin-2-amine CAS 152460-09-8 Imatinib Mesylate Intermediate High Purity

N-(2-Methyl-5-nitrophenyl)-4-(pyridin-3-yl)pyrimidin-2-amine CAS 152460-09-8 Imatinib Mesylate Intermediate High Purity

Incazelo emfushane:

N-(2-Methyl-5-nitrophenyl)-4-(pyridin-3-yl)pyrimidin-2-amine

I-CAS: 152460-09-8

Ukubukeka: Impushana Ephuzi noma Cishe Ephuzi

Ubumsulwa: ≥98.0% (HPLC)

I-Imatinib Mesylate ephakathi (CAS: 220127-57-1) ekwelapheni i-Philadelphia Chromosome-Positive Chronic Myeloid Leukemia (Ph + CML)

Ikhwalithi Ephezulu, Ukukhiqizwa Kwezohwebo

Inquiry: alvin@ruifuchem.com


Imininingwane Yomkhiqizo

Imikhiqizo Ehlobene

Omaka bomkhiqizo

Incazelo:

Ukunikezwa Kwezohwebo I-Imatinib Mesylate kanye Nezixhumanisi Ezihlobene:
I-Imatinib Mesylate CAS: 220127-57-1
N-(2-Methyl-5-nitrophenyl)-4-(pyridin-3-yl)pyrimidin-2-amine CAS: 152460-09-8
N-(5-Amino-2-methylphenyl)-4-(3-pyridyl)-2-pyrimidinea CAS: 152460-10-1
4--[(4-Methylpiperazin-1-yl)methyl]benzoic acid dihydrochloride CAS: 106261-49-8

Chemical Properties:

Igama Lekhemikhali N-(2-Methyl-5-nitrophenyl)-4-(pyridin-3-yl)pyrimidin-2-amine
Omqondofana I-Imatinib Mesylate Intermediate;2-(2-Methyl-5-nitroanilino)-4-(3-pyridyl)pyrimidine
Inombolo ye-CAS 152460-09-8
Inombolo yeCAT I-RF-PI228
Isimo Sesitoko Esitokweni, Isikali Sokukhiqiza Sifinyelela Kumathani
I-Molecular Formula I-C16H13N5O2
Isisindo samangqamuzana 307.31
I-Melting Point 188.0~193.0℃
Ibhrendi I-Ruifu Chemical

Imininingwane:

Into Imininingwane
Ukubukeka Impushana Ephuzi noma Cishe Ephuzi
Ubumsulwa ≥98.0% (HPLC)
Umswakama (KF) ≤0.50%
Ukungcola Okuphelele ≤2.0%
Ukungcola Okukodwa Okukhulu ≤1.0%
Izinsalela ekushiseni ≤0.50%
Izinsimbi Ezisindayo ≤20ppm
Izinga Lokuhlola I-Enterprise Standard
Ukusetshenziswa Okumaphakathi kwe-Imatinib Mesylate (CAS: 220127-57-1)

Iphakheji nesitoreji:

Iphakheji: Ibhodlela, isikhwama se-Aluminium foil, isigubhu seCardboard, 25kg/Drum, noma ngokwezidingo zekhasimende.

Isimo Sesitoreji:Gcina ezitsheni ezivaliwe endaweni epholile neyomile;Vikela ekukhanyeni, umswakama kanye nezinambuzane.

Izinzuzo:

1

I-FAQ:

Isicelo:

I-Shanghai Ruifu Chemical Co., Ltd. ingumkhiqizi oholayo nomnikezeli we-N-(2-Methyl-5-nitrophenyl)-4-(pyridin-3-yl)pyrimidin-2-amine (CAS: 152460-09-8) ngekhwalithi ephezulu.Kuyinto ephakathi ngokuvamile ekuhlanganiseni kwe-Imatinib Mesylate (CAS: 220127-57-1).
I-Imatinib Mesylate iyingqamuzana encane evimbela i-c-Abl protein-tyrosine kinase, Iqonde kakhulu i-BCR-ABL, i-enzyme ehlotshaniswa ne-chronic myelogenous leukemia (CML) kanye nezinhlobo ezithile ze-acute lymphoblastic leukemia (YONKE).Umcimbi wokuthutha phakathi kwama-chromosome 9 kanye no-22 ukhiqiza i-chromosome yase-Philadelphia, ebese ikhiqiza iphrotheni ye-Bcr-Abl fusion enomsebenzi we-aberrant kinase okhuthaza ukwanda okusheshayo kwamaseli.I-Imatinib Mesylate ihlanganisa le kinase ebalulekile, imisa ukukhula okuhlobene ne-CML.I-Imatinib Mesylate iphinde yaboniswa ukuze ivimbele i-PDGFR kanye ne-tyrosine kinases ehlotshaniswa ne-c-Kit.Amafomula aqukethe i-Imatinib Mesylate asetshenziswe ekwelapheni umdlavuza ohlukahlukene.

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