I-Indapamide CAS 26807-65-8 Purity ≥99.5% (HPLC) API EP Factory Standard High Quality
I-Shanghai Ruifu Chemical Co., Ltd. ingumkhiqizi oholayo nomphakeli we-Indapamide nabaxhumanisi abahlobene nabo abanekhwalithi ephezulu.
I-Indapamide CAS 26807-65-8
I-2-Methylindoline CAS 6872-06-6
I-1-Amino-2-Methylindoline Hydrochloride CAS 102789-79-7
| Igama Lekhemikhali | Indapamide |
| Omqondofana | N-(4-Chloro-3-Sulfamoylbenzamido)-2-Methylindoline |
| Inombolo ye-CAS | 26807-65-8 |
| Isimo Sesitoko | Esitokweni, Isikali Sokukhiqiza Sifinyelela Kumathani |
| I-Molecular Formula | I-C16H16ClN3O3S |
| Isisindo samangqamuzana | 365.83 |
| I-Melting Point | 160.0 ~ 162.0℃ |
| Ibhrendi | I-Ruifu Chemical |
| Into | Imininingwane |
| Ukubukeka | I-Crystalline Powder Emhlophe noma Cishe Emhlophe |
| Ukuncibilika | Ayincibiliki Emanzini;Incibilika ku-Ethanol |
| Ukuhlonza A | I-Ultraviolet kanye ne-Visible Absorption Spectrophotometry |
| Ukuhlonza B | I-Infrared Absorption Spectrophotometry |
| Ukuhlonza C | I-Chromatography yongqimba oluncane |
| Ukujikeleza kwe-Optical | -0.80°~ +0.80° (C=5, C2H5OH) |
| Amanzi (EP 2.5.12) | <3.00% |
| I-Sulphated Ash (EP 2.4.14) | <0.10% |
| I-Heavy Metals (EP 2.4.8) | <10ppm |
| Izinto Ezihlobene | |
| Ukungcola B | <0.30% |
| Ukungcola Okungashiwongo | <0.10% |
| Ukungcola Okuphelele | <0.50% |
| Ukuhlanzeka / Indlela Yokuhlaziya | >99.5% (HPLC) |
| Izinga Lokuhlola | I-EP Standard |
| Ukusetshenziswa | I-API;I-Antihypertensive kanye ne-A diuretic |
Iphakheji: Ibhodlela, isikhwama se-Aluminium foil, 25kg/Cardboard Drum, noma ngokwezidingo zekhasimende.
Isimo Sesitoreji:Gcina ezitsheni ezivaliwe endaweni epholile neyomile;Vikela ekukhanyeni nakumswakama.
I-Indapamide (CAS: 26807-65-8) iyi-antihypertensive kanye ne-diuretic.Ngokuvimbela ukumuncwa kabusha kwe-Na+ ekugcineni okuseduze kwe-distal conflexion tubules, ikhiqiza umphumela we-diuretic futhi ivimbela ukungena kwe-Ca2+.Inokukhethwa okuphezulu kwemisipha ebushelelezi ye-vascular, ivula imikhumbi emincane ye-peripheral futhi ikhiqize umphumela we-hypotensive.Kepha umphumela ku-vascular smooth muscle umphumela we-diuretic unamandla, ngaphansi kwemithamo ye-diuretic ungahla, imithamo ephezulu ikhombisa umphumela we-diuretic, kepha akukho ukushiyeka kwe-thiazide diuretic, okungukuthi okungabangeli i-orthostatic hypotension, i-flush kanye ne-reflect tachycardia, esithombeni segazi, imetabolism yegazi. amafutha, ushukela kanye nokusebenza kwezinso nakho akubanga nomphumela osobala, imithamo yokwelapha yokushaya kwenhliziyo, ukuphuma kwenhliziyo, akukho zinguquko eziphawulekayo ku-electrocardiogram (ecg) were It has no effect osobala on central nervous system and autonomic nerve.Ukuphathwa ngomlomo kwe-2 ~ 3 chemicalbook H kukhiqize umphumela we-hypotensive, owagcinwa amahora angu-24.Umphumela we-diuretic uvele ngo-3h futhi ufinyelele umphumela wawo omkhulu ngo-4 ~ 6h.I-Indapamide ilungele umfutho wegazi ophakeme ophansi futhi olinganiselayo, futhi ingasetshenziselwa ukwehluleka kwenhliziyo okugcwala okubangelwa ukugcinwa kwe-sodium emanzini, ngokwehluleka kwezinso kuyasebenza nasezigulini ezinomfutho wegazi ophakeme, isifo sikashukela, i-hyperlipidemia, ukusetshenziswa kwe-antihypertensive effect kuyaphawuleka.
