I-Indomethacin CAS 53-86-1 Purity >99.5% (HPLC) Factory High Purity
I-Shanghai Ruifu Chemical Co., Ltd. ingumkhiqizi oholayo nomphakeli we-Indomethacin (CAS: 53-86-1) enekhwalithi ephezulu, ukukhiqizwa kwezentengiso.Wamukelekile eku-odeni.
Igama Lekhemikhali | I-Indomethacin |
Omqondofana | I-Indometacin;1-(4-Chlorobenzoyl)-5-Methoxy-2-Methyl-3-Indoleacetic Acid |
Inombolo ye-CAS | 53-86-1 |
Inombolo yeCAT | I-RF-PI1601 |
Isimo Sesitoko | Esitokweni, Isikali Sokukhiqiza Sifinyelela Kumathani |
I-Molecular Formula | I-C19H16ClNO4 |
Isisindo samangqamuzana | 357.79 |
I-Solubility ku-Hot Methanol | Cishe Ukungafihli |
Ukuncibilika kwamanzi | Ayincibiliki Emanzini |
Ibhrendi | I-Ruifu Chemical |
Into | Imininingwane |
Ukubukeka | I-Crystalline Powder Emhlophe Kuya Kuphuzi Ephuzi |
Ukuhlonza | Okuhle |
I-Melting Point | 158.0~162.0℃ |
Ukulahlekelwa Ekumisweni | ≤0.50% |
Izinsalela ekushiseni | ≤0.20% |
Ukungcola Okukodwa | ≤0.30% |
Ukungcola Okuphelele | ≤0.50% |
Izinsimbi Ezisindayo | ≤20ppm |
Ukuhlanzeka / Indlela Yokuhlaziya | ≥99.5% (HPLC) |
Izinga Lokuhlola | I-Enterprise Standard |
Ukusetshenziswa | I-API;Pharmaceutical Intermediates |
Iphakheji: Ibhodlela, isikhwama se-Aluminium foil, 25kg/Cardboard Drum, noma ngokwezidingo zekhasimende.
Isimo Sesitoreji:Gcina ezitsheni ezivaliwe endaweni epholile neyomile;Vikela ekukhanyeni nakumswakama.
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I-Indomethacin (i-CAS: 53-86-1) iyisidakamizwa esingeyona i-steroidal anti-inflammatory (NSAID) evame ukusetshenziswa njengemithi kadokotela ukuze kuncishiswe umkhuhlane, ubuhlungu, ukuqina, nokuvuvukala.Isebenza ngokuvimbela ukukhiqizwa kwama-prostaglandin, ama-molecule aziwa ukuthi abangela lezi zimpawu.Ifana ne-ibuprofen (Motrin) ne-naproxen (Naprosyn, Aleve).I-Indomethacin isebenza ngokunciphisa ukukhiqizwa kwe-prostaglandin.I-Prostaglandin ngamakhemikhali akhiqizwa umzimba futhi abangela umkhuhlane nobuhlungu obuhambisana nokuvuvukala.I-Indomethacin ivimba ama-enzyme enza i-prostaglandin (i-cyclooxygenase 1 no-2) futhi ngaleyo ndlela yehlise amazinga e-prostaglandin.Ngenxa yalokho, umkhuhlane, ubuhlungu nokuvuvukala kuyancishiswa.I-Indomethacin iyatholakala ngefomu lokukhululwa elinwetshiwe.I-FDA yagunyaza okokuqala i-indomethacin ngoJanuwari 1965.
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