Inosine CAS 58-63-9 Assay 98.0~102.0% Factory High Quality

I-Inosine (CAS: 58-63-9) Indlela Yokuhlola ye-ChP2020
Inosine - DEFINITION
Okuqukethwe kwe-C10H12N4O5 kuzoba phakathi kuka-98.0% no-102.0% kubalwe kumkhiqizo owomisiwe.
Inosine - Trait Lo mkhiqizo uyimpushana emhlophe ecwebezelayo;Ayinaphunga.Lo mkhiqizo uncibilika kancane emanzini, awuncibiliki ku-ethanol, futhi uncibilika ku-dilute hydrochloric acid nesisombululo se-sodium hydroxide.
Inosine - IDENTIFICATION
1. Thatha inani elifanele lesixazululo esingu-0.01% salo mkhiqizo, engeza umthamo olinganayo we-3, 5-dihydroxytoluene solution (thatha 3, 5-dihydroxytoluene kanye ne-ferric chloride 0.lg, engeza i-hydrochloric acid ukwenza i-100ml), hlanganisa kahle, ngemva ukushisa emanzini okugeza amanzi cishe imizuzu eyi-10, umbala oluhlaza ubonwe.
2. Kuchromatogram erekhodwe ngaphansi kwento yokunquma okuqukethwe, isikhathi sokugcinwa kwenani eliphakeme lesixazululo sokuhlola kufanele sihambisane nesikhathi sokugcinwa kwenani eliphakeme lesixazululo sereferensi.
3. I-spectrum yokumuncwa kwe-infrared yalo mkhiqizo kufanele ihambisane naleyo yokulawula (I-Spectrum set 605).
Inosine - Ukuhlaziywa
Ukudluliswa Kwesixazululo
Thatha u-0.5g walo mkhiqizo, engeza u-50ml wamanzi ukuze uncibilike, ngokuya nge-spectrophotometry ebonakalayo ye-UV (Umthetho ojwayelekile 0401), nquma ukudlulisa ku-430nm wavelength, hhayi ngaphansi kuka-98.0%.(Okomjovo)
Izinto Ezihlobene
Thatha lo mkhiqizo, engeza amanzi ukuze uhlakaze futhi uhlambulule ukuze wenze isisombululo esiqukethe i-0.5mg nge-1ml ngayinye njengesixazululo sokuhlola;Thatha i-1ml yokulinganisa okunembayo, uyibeke ku-flask yokulinganisa engu-100ml, uyihlambulule ngamanzi esikalini, njengesixazululo sokulawula.Ngokwezimo ze-chromatographic ngaphansi kwento yokunqunywa kokuqukethwe, i-20 u1 yesisombululo sokuhlola kanye nesixazululo sokulawula kufakwa ngokulandelana ku-chromatograph ewuketshezi, futhi i-chromatogram irekhodwa izikhathi ezi-2 zesikhathi sokugcinwa kwenani eliphakeme kakhulu.Uma kukhona iziqongo zokungcola ku-chromatogram yesixazululo sokuhlola, isamba sendawo ngayinye yokungcola akufanele sibe sikhulu kunendawo eyinhloko yesixazululo sokulawula (1.0%).
Ukulahlekelwa Ekumisweni
Thatha lo mkhiqizo, womile kuya esisindweni esingaguquki ku-105°C, ukuncipha kwesisindo akumele kudlule u-1.0% (Umthetho ojwayelekile 0831).
Izinsalela ekushiseni (Sulfated)
Angabi ngaphezu kuka-0.1% (womjovo), noma angabi ngaphezu kuka-0.2% (okusetshenziswa ngomlomo) (Umthetho ojwayelekile 0841).
Izinsimbi Ezisindayo
Thatha lo mkhiqizo 1.0g, ukuhlola ngokomthetho (General Principles 0821 umthetho wesibili), oqukethe izinsimbi ezisindayo ngeke kweqe izingxenye 10 esigidini ngasinye.
Ubuthi obungajwayelekile
Thatha lo mkhiqizo, engeza umjovo we-sodium chloride ukuze uncibilikise futhi uhlambulule isisombululo esiqukethe inosine 10mg nge-1ml ngayinye, hlola ngokomthetho (Umthetho jikelele we-1141), kufanele uhambisane nezinhlinzeko.(Okomjovo)
Inosine - Ukuzimisela kokuqukethwe
Kukalwa Nge-High Performance Liquid Chromatography (Okujwayelekile 0512).
Izimo zeChromatographic nokufaneleka kwesistimu yokuhlola ijeli ye-silica ehlanganiswe ne-alkyl silane eyishumi nesishiyagalombili yasetshenziswa njengesigcwalisi;I-Methanol-water (10:90) yayisetshenziswa njengesigaba esihambayo;Ubude bokutholwa bebungu-248nm.Thatha cishe u-10mg wereferensi ye-inosine, engeza i-1 mol/L ye-hydrochloric acid solution (1ml), ukushisa emanzini okugeza ngo-80 ℃ imizuzu engu-10, uyeke kuphole, wengeze u-1ml we-1 mol/L ye-sodium hydroxide, engeza amanzi ku-50ml, I-chromatograph ewuketshezi yomjovo we-20u1, lungisa isistimu ye-chromatographic, idigri yokuhlukaniswa kwe-inosine peak kanye nenani eliphakeme lokungcola eliseduze kufanele lihlangabezane nezidingo, inani lepuleti lethiyori ngokuya ngokubala kwe-inosine peak alikho ngaphansi kuka-2000.
Isivivinyo
Thatha inani elifanele lalo mkhiqizo, ukale kahle, ungeze amanzi ukuze uwancibilikise futhi uwahlambulule ngobuningi ukuze wenze isixazululo esiqukethe cishe u-20ug nge-lml ngayinye, uyinyakazise, ​​futhi uyisebenzise njengesixazululo sokuhlola, I-chromatograph engama-20ul ewuketshezi yomjovo yalinganiswa ngokunembile futhi. i-chromatogram yarekhodwa.Inani elifanele lereferensi ye-inosine lakalwa ngokunembile futhi lanqunywa ngendlela efanayo, futhi indawo ephakemeyo yabalwa ngokuvumelana nendlela evamile yangaphandle.
Inosine - Isigaba
Izidakamizwa ezithuthukisa i-cell metabolism.
Inosine - Isitoreji
Isivikelo esilula, isitoreji esivaliwe.
Ezemithi: (1) Inosine Oral Solution (2) Inosine Tablets (3) Inosine Injection (4) Inosine Capsules (5) Inosine kanye neGlucose Injection (6) Inosine kanye neSodium Chloride Injection (7) Inosine Yomjovo