I-Irbesartan Intermediate Side Side Chain Hydrochloride CAS 151257-01-1 Purity >99.0% (HPLC) Factory
I-Ruifu Chemical Supply Irbesartan Intermediates:
I-Irbesartan CAS 138402-11-6
I-Cyano-Irbesartan CAS 138401-24-8
I-Trityl Irbesartan CAS 138402-10-5
I-TTBB CAS 124750-51-2
I-Irbesartan Side Chain Hydrochloride CAS 151257-01-1
Igama Lekhemikhali | 2-Butyl-1,3-diazaspiro[4.4]non-1-en-4-one Hydrochloride |
Omqondofana | I-Irbesartan Side Chain Hydrochloride;I-Irbesartan Lactam Ukungcola;Ukungcola kwe-Irbesartan A;I-2-Butyl-4-spirocyclopentane-2-imidazolin-5-one Hydrochloride;2-Butyl-1,3-diaza-spiro[4.4]non-1-en-4-one HCl |
Inombolo ye-CAS | 151257-01-1 |
Inombolo yeCAT | I-RF-PI1894 |
Isimo Sesitoko | Esitokweni, Isikali Sokukhiqiza Sifinyelela Kumathani |
I-Molecular Formula | I-C11H18N2O·HCl |
Isisindo samangqamuzana | 230.74 |
Ukuncibilika Emanzini | Incibilika Emanzini |
I-Melting Point | 235.0~240.0℃ |
Ibhrendi | I-Ruifu Chemical |
Into | Imininingwane |
Ukubukeka | I-Crystalline Powder Emhlophe kuya Kucishe Emhlophe |
Ukuhlanzeka / Indlela Yokuhlaziya | >99.0% (HPLC) |
Ukulahlekelwa Ekumisweni | <0.50% |
Izinsalela ekushiseni | <0.20% |
Ukungcola Okuphelele | <1.00% |
I-Proton NMR Spectrum | Ivumelana Nesakhiwo |
Izinga Lokuhlola | I-Enterprise Standard |
Ukusetshenziswa | I-Irbesartan emaphakathi (CAS: 138402-11-6) |
Iphakheji: Ibhodlela, isikhwama se-Aluminium foil, 25kg/Cardboard Drum, noma ngokwemfuneko yekhasimende
Isimo Sesitoreji:Gcina ezitsheni ezivaliwe endaweni epholile neyomile;Vikela ekukhanyeni nakumswakama
I-2-Butyl-1,3-diazaspiro[4.4]non-1-en-4-one Hydrochloride (CAS: 151257-01-1), eyaziwa nangokuthi i-Irbesartan Side Chain Hydrochloride, iyi-Intermediate ye-Irbesartan (Avapro) (CAS : 138402-11-6).I-Irbesartan iyi-angiotensin II receptor inhibitor, i-angiotensin II receptors ihlukaniswe yaba yi-AT1, AT2, i-irbesartan ingavimbela i-AngⅠtransform ibe i-AngII ngokuvimba ngokukhetha i-AT1 receptor ye-AngII, ikakhulukazi iphikisana ne-angiotensin eguqula i-enzyme 1 receptor (AT500), i-antagonism ye-AT500 izikhathi kunalezo ze-AT2, ingavimbela i-vasoconstriction kanye nokukhululwa kwe-aldosterone ngokukhetha ngokukhethayo i-AngII ebophayo nge-AT1 receptor futhi kubangele umphumela we-antihypertensive.Lo mkhiqizo awuvimbeli i-angiotensin converting enzyme (ACE), i-renin, namanye ama-hormone receptors, futhi awucindezeli ukulawulwa komfutho wegazi kanye nebhalansi yamashaneli e-sodium ion.I-Irbesartan inganciphisa nokulungiswa kabusha kukagesi kwe-myocardium, ngaleyo ndlela yehlise izinga lokufa kweziguli ezinomfutho wegazi ophakeme, iwumuthi osebenza kahle kakhulu ekwelapheni umfutho wegazi ophakeme kanye nesifo senhliziyo.