I-Irinotecan Free Base CAS 97682-44-5 Assay ≥99.0% (HPLC) API Factory High Purity
Umkhiqizi Uhlinzeka Nge-Irinotecan kanye Nezixhumanisi Ezihlobene:
I-Irinotecan Hydrochloride CAS: 100286-90-6
I-Irinotecan Free Base CAS: 97682-44-5
I-Irinotecan Hydrochloride Trihydrate CAS: 136572-09-3
I-7-Ethyl-10-Hydroxycamptothecin CAS: 86639-52-3
I-1-Chlorocarbonyl-4-Piperidinopiperidine Hydrochloride CAS: 143254-82-4
| Igama Lekhemikhali | I-Irinotecan Free Base |
| Inombolo ye-CAS | 97682-44-5 |
| Inombolo yeCAT | I-RF-API51 |
| Isimo Sesitoko | Esitokweni, Isikali Sokukhiqiza Sifinyelela Kumathani |
| I-Molecular Formula | I-C33H38N4O6 |
| Isisindo samangqamuzana | 586.68 |
| I-Melting Point | 222.0-223.0℃ |
| Isimo Sokuthumela | Ngaphansi Kwezinga Lokushisa Le-Ambient |
| Ibhrendi | I-Ruifu Chemical |
| Into | Imininingwane |
| Ukubukeka | Impushana Ephuzi Ekhanyayo |
| Ukuhlonza HPLC | Isikhathi sokugcinwa kwesampula sihambisana naleso se-RS |
| Ukulahlekelwa Ekumisweni | ≤5.0% |
| I-Single Max.Ukungcola | ≤0.25% |
| Ukungcola Okuphelele | ≤1.0% |
| Isivivinyo | ≥99.0% (HPLC) |
| Izinga Lokuhlola | I-Enterprise Standard |
| Ukusetshenziswa | I-API |
Iphakheji: Ibhodlela, isikhwama se-Aluminium foil, isigubhu seCardboard, 25kg/Drum, noma ngokwezidingo zekhasimende.
Isimo Sesitoreji:Gcina ezitsheni ezivaliwe endaweni epholile neyomile;Vikela ekukhanyeni, umswakama kanye nezinambuzane.
I-Irinotecan Free base iyi-analog ye-camptothecin kanye ne-topoisomerase I inhibitor.Ingase ivimbele i-AChE.I-Irinotecan Free base isetshenziselwa ukwelapha umdlavuza wekoloni, kodwa futhi yengamela ukuvinjwa kokuhlukaniswa kwamaseli e-dendritic futhi yehlise inani lemikhumbi yesimila kumamodeli e-glioma.I-Irinotecan ivimbela ukuhlanganiswa kwe-DNA strand ngokubophezela ku-topoisomerase I-DNA complex.Ukwakheka kwale ternary complex kuphazamisa imfoloko ephindaphindayo ehambayo, eyenza ukuthi kuboshwe ukuphindaphinda kanye namakhefu abulalayo anemicu ekabili ku-DNA.
