I-Ivabradine Hydrochloride CAS 148849-67-6 Purity >99.5% (HPLC) API Factory
I-Ruifu Chemical Supply Ivabradine Hydrochloride Intermediates With High Purity
I-Ivabradine Hydrochloride CAS 148849-67-6
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Igama Lekhemikhali | I-Ivabradine Hydrochloride |
Omqondofana | I-Ivabradine HCl |
Inombolo ye-CAS | 148849-67-6 |
Inombolo yeCAT | I-RF-PI1812 |
Isimo Sesitoko | Esitokweni, Isikali Sokukhiqiza Sifinyelela Kumathani |
I-Molecular Formula | C27H36N2O5·HCl |
Isisindo samangqamuzana | 505.05 |
Ibhrendi | I-Ruifu Chemical |
Into | Imininingwane |
Ukubukeka | I-Crystalline Powder emhlophe ukuya kokumhlophe |
Ukuhlonza | I-HPLC/UV Iyahambisana |
Ukuhlanzeka / Indlela Yokuhlaziya | >99.5% |
Ukulahlekelwa Ekumisweni | <1.00% (Yomise ku-105℃ kumshini wokomisa womoya kagesi kuze kube nesisindo esingashintshi) |
Okuqukethwe Umswakama | <1.00% |
Izinsalela ekushiseni | <0.20% |
Ukungcola Okukodwa Okukhulu | <0.50% |
Ukungcola Okuphelele | <0.50% |
Isomer ye-Optical | <0.50% |
Isivivinyo | >99.5% |
Izinsimbi Ezisindayo | <20ppm |
Ukuzungezisa okuqondile | +6.5° ~ +8.5° (omisiwe, isisombululo esingu-1% ku-DMSO) |
Izinga Lokuhlola | I-Enterprise Standard |
Ukusetshenziswa | I-API |
Iphakheji: Ibhodlela, isikhwama se-Aluminium foil, 25kg/Cardboard Drum, noma ngokwemfuneko yekhasimende
Isimo Sesitoreji:Gcina ezitsheni ezivaliwe endaweni epholile neyomile;Vikela ekukhanyeni nakumswakama
I-Ivabradine Hydrochloride (CAS: 148849-67-6),Emzamweni wokuthuthukisa ama-angina agents ngaphandle kwemiphumela engemihle ye-inotropic ne-hypotensive ehlobene ne-b-adrenergic blockers kanye ne-calcium channel blockers, isigaba esisha sezinhlanganisela zokunciphisa ukushaya kwenhliziyo ezisebenza ngokuqondile ku-node ye-sinoatrial (SA) iye yahlolwa.Lawa ma-ejenti e-bradycardic asebenzisana ngqo ne-pacemaking cell ye-SA node kanye ne-hyperpolarization- activated Uma i-primary pacemaking current.I-Ivabradine iye yavela njenge-inhibitor ethize ye-If yamanje ngokuthintana kwayo ne-f-channels ohlangothini lwe-intracellular lwe-membrane ye-plasma.Ngenxa yalokho, i-Ivabradine yehlisa isivinini se-diastolic depolarization futhi yehlise izinga lokushaya kwenhliziyo.Igunyazwe ukwelashwa kwe-angina engapheli futhi inikeza enye indlela esebenzayo ezigulini ezine-contraindication noma ukungabekezelelani kwe-b-blockers.Ukuhlolwa kuyaqhubeka nokwelashwa okungenzeka kwesifo senhliziyo ye-ischemic.