I-Ketorolac CAS 74103-06-3 Ubumsulwa >98.5% (HPLC)
I-Shanghai Ruifu Chemical Co., Ltd. ingumkhiqizi ohamba phambili we-Ketorolac (CAS: 74103-06-3) enekhwalithi ephezulu.I-Ruifu Chemical ingahlinzeka ngokulethwa komhlaba wonke, amanani ancintisanayo, amanani amancane nayinqwaba atholakalayo.Thenga i-Ketorolac,Please contact: alvin@ruifuchem.com
| Igama Lekhemikhali | I-Ketorolac |
| Omqondofana | I-5-Benzoyl-2,3-Dihydro-1H-Pyrrolizine-1-Carboxylic Acid;I-5-Benzoyl-2,3-Dihydro-1h-Pyrrolo[1,2-a]pyrrole-1-Carboxylic Acid;(±)-Ketorolac;I-Acular LS;I-Keromin;i-Ketorolac;I-Toradol |
| Isimo Sesitoko | Kukhona kusitoki |
| Inombolo ye-CAS | 74103-06-3 |
| I-Molecular Formula | I-C15H13NO3 |
| Isisindo samangqamuzana | 255.27 g/mol |
| I-Melting Point | 159.0~161.0℃ |
| Ukuminyana | 1.33±0.10 g/cm3 |
| Isikhathi Sokugcina. | Indawo epholile neyomile (2~8℃) |
| I-COA ne-MSDS | Iyatholakala |
| Ibhrendi | I-Ruifu Chemical |
| Izinto | Amazinga Wokuhlola | Imiphumela |
| Ukubukeka | I-Off-White Crystalline Powder | Iyahambisana |
| I-Melting Point | 159.0~161.0℃ | 159.5℃ |
| Ukulahlekelwa Ekumisweni | <0.50% | 0.2% |
| Izinsalela ekushiseni | <0.10% | 0.062% |
| Ubukhulu.Ukungcola Okukodwa | <1.00% | 0.48% |
| Izinsimbi Ezisindayo (njenge-Pb) | ≤10ppm | 6 ppm |
| Ukuhlanzeka / Indlela Yokuhlaziya | >98.5% (HPLC) | 99.0% |
| I-Proton NMR Spectrum | Ivumelana Nesakhiwo | Iyahambisana |
| Isiphetho | Umkhiqizo uhloliwe futhi uthobelana nezicaciso | |
Iphakheji:Ibhodlela, isikhwama se-Aluminium foil, 25kg/Cardboard Drum, noma ngokwezidingo zekhasimende.
Isimo Sesitoreji:Gcina esitsheni esivalwe ngci.Gcina endaweni epholile, eyomile (2~8℃) futhi enomoya omuhle kude nezinto ezingahambelani.Vikela ekukhanyeni nakumswakama.
Ukuthumela:Zilethe emhlabeni wonke ngendiza, yi-FedEx/DHL Express.Nikeza ukulethwa okusheshayo nokuthembekile.
Indlela Yokuthenga?Sicela uxhumaneDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
Iminyaka engu-15 Yokuhlangenwe nakho?Sinesipiliyoni seminyaka engaphezu kwe-15 ekwakhiweni nasekuthumeleni kwamanye amazwe uhla olubanzi lwezinga eliphezulu lokuxhumanisa imithi noma amakhemikhali amahle.
Izimakethe Eziyinhloko?Thengisa emakethe yasekhaya, eNyakatho Melika, eYurophu, eNdiya, eKorea, eJapane, e-Australia, njll.
Izinzuzo?Ikhwalithi ephezulu, intengo ethengekayo, izinsizakalo ezichwepheshile nokusekelwa kobuchwepheshe, ukulethwa okusheshayo.
IkhwalithiIsiqiniseko?Isistimu yokulawula ikhwalithi eqinile.Imishini yobuchwepheshe yokuhlaziya ifaka i-NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, NOMA, KF, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, njll.
Amasampula?Imikhiqizo eminingi inikeza amasampula wamahhala wokuhlolwa kwekhwalithi, izindleko zokuthumela kufanele zikhokhelwe amakhasimende.
Ukuhlolwa Kwemboni?Wamukelekile ekucwaningweni kwemboni.Sicela wenze i-aphoyintimenti kusengaphambili.
I-MOQ?Ayikho i-MOQ.I-oda elincane liyamukeleka.
Isikhathi sokuthumela? Uma kungaphakathi kwesitoko, ukulethwa kwezinsuku ezintathu kuqinisekisiwe.
Ezokuthutha?By Express (FedEx, DHL), by Air, by Sea.
Amadokhumenti?Ngemuva kwenkonzo yokuthengisa: I-COA, i-MOA, i-ROS, i-MSDS, njll.
Custom Synthesis?Ingahlinzeka ngezinsizakalo zokwenziwa ngokwezifiso ukuze zilingane kangcono nezidingo zakho zocwaningo.
Imigomo Yokukhokha?I-invoyisi ye-Proforma izothunyelwa kuqala ngemva kokuqinisekiswa kwe-oda, kufakwe nemininingwane yethu yasebhange.Inkokhelo nge-T/T (Telex Transfer), PayPal, Western Union, njll.
I-RIDADR 3249
I-Hazard Class 6.1(a)
PackingGroup II
I-HS Code 2933998090
Ubuthi LD50 ngomlomo kumagundane: ~200 mg/kg (Rooks)
I-Ketorolac (i-CAS: 74103-06-3) iyisidakamizwa esingeyona i-steroid analgesic kanye ne-anti-inflammatory, i-derivative ye-pyrrolidone.Isakhiwo samakhemikhali kanye nesenzo se-pharmacological sifana ne-Tolectin, i-Zoaesthetic acid ne-Indometacin.Ngokuvimbela i-cyclooxygenase, ivimbela ukuhlanganiswa nokukhululwa kwe-prostaglandin, futhi ikhiqize imiphumela ephikisana nokuvuvukala.Ingakwazi ukunciphisa izinga lokushisa elibangelwa umthombo wokushisa, okuhlobene nokuvinjelwa kokuhlanganiswa kwe-prostaglandin ohlelweni lwezinzwa oluphakathi.Inomphumela oqinile we-analgesic kanye ne-anti-inflammatory antipyretic kanye nokuvinjelwa kwe-platelet aggregation, futhi ayinakho ukuvinjelwa kokuphefumula futhi ukulutheka.Ekuhlolweni kwezilwane, umphumela we-analgesic unamandla kune-aspirin, i-indomethacin ne-naproxen.Ilingana noma ingcono kunomphumela wokulwa nokuvuvukala we-naproxen ne-indomethacin, i-phenylbutazone,Umphumela wayo we-antipyretic kumagundane unamandla kune-aspirin ne-phenylbutazone futhi kuyafana I-indomethacin ne-naproxen.Ivimbela ukuhlanganiswa kweplatelet okubangelwa i-arachidonic acid ne-collagen.Kodwa akuvimbeli ukufakwa kwe-adenosine diphosphate (ADP).Lo mkhiqizo udonswa ngokushesha futhi ngokuphelele ngemva komjovo we-intramuscular, futhi ucishe ugxile ngokuphelele ngemva kokuphathwa ngomlomo.Ukudla kunganciphisa ijubane lokumunca, kodwa akuthinti izinga lokumunca, futhi i-bioavailability i-80% ~ 100%.Imizuzu eyi-10 ngemuva komjovo we-intramuscular of 30mg, imvamisa ikhulula izinhlungu ngokusobala.Ngemuva kwemizuzu engama-50, inani eliphakeme lokuhlushwa kwe-plasma lifinyelela ku-2.2 g/mL.Ngemuva kwemizuzu engu-30 ~ 60 yokuphathwa ngomlomo, ubuhlungu buyancipha ngokusobala futhi ukugxila kwe-plasma kufinyelela ku-1.5 amahora angu-4.Ukuphila kwesigamu se-plasma yabantu abasha cishe amahora angu-5.3, futhi kubantu asebekhulile cishe amahora angu-7, futhi umphumela we-analgesic ungagcinwa amahora angu-6 ~ 8.I-91.4% izokhishwa emgudwini womchamo, okusele kuzokhishwa endle.Ezigulini ezinokwehluleka kwezinso, inani lokuqedwa kwe-plasma liyancipha futhi isigamu sokuphila siyandisa, ngakho-ke umthamo kufanele uncishiswe.
Isicelo somtholampilo: I-Ketorolac isetshenziselwa kakhulu ukwelashwa kwezinhlungu zesikhashana ezihlanganisa ubuhlungu bangemva kokuhlinzwa (okufana nesisu, isifuba, i-Urology, i-gynecology, uMnyango We-Stomatology, ukuhlinzwa kwamathambo nobuhlungu) kanye nobuhlungu obukhulu bemisipha obubangelwa izimbangela ezihlukahlukene, njenge-sprain, i-dislocation, i-fracture kanye nokulimala kwezicubu ezithambile, nobunye ubuhlungu obubangelwa ezinye izifo, njengobuhlungu be-postpartum, i-acute renal colic, ubuhlungu bezinyo, i-sciatica, ubuhlungu bomdlavuza sekwephuzile, ubuhlungu benxeba, i-biliary colic, njll. Ingasetshenziswa esikhundleni se-morphine ne-pethidine.
