I-L-Alaninamide Hydrochloride CAS 33208-99-0 (H-Ala-NH2·HCl) I-Assay 98.0~102.0% I-Safinamide Intermediate Factory
I-Shanghai Ruifu Chemical Co., Ltd. ingumkhiqizi oholayo nomphakeli we-L-Alaninamide Hydrochloride (H-Ala-NH2·HCl) (CAS: 33208-99-0) enekhwalithi ephezulu, emaphakathi ye-Safinamide (CAS: 133865- 89-1).Singahlinzeka ngokudiliva emhlabeni wonke, amanani amancane futhi ngobuningi atholakalayo.Uma udinga i-L-Alaninamide Hydrochloride,Please contact: alvin@ruifuchem.com
Igama Lekhemikhali | I-L-Alaninamide Hydrochloride |
Omqondofana | I-L-Alaninamide HCl;H-Ala-NH2·HCl;L-Ala-NH2·HCl;(S) -2-Aminopropionamide Hydrochloride;(S) -2-Aminopropionamide HCl;(2S) -2-Aminopropanamide Hydrochloride |
Isimo Sesitoko | Esitokweni, Amandla Okukhiqiza Amathani ayi-100 ngonyaka |
Inombolo ye-CAS | 33208-99-0 |
I-Molecular Formula | C3H8N2O·HCl |
Isisindo samangqamuzana | 124.57 g/mol |
I-Melting Point | 200.0 ~ 220.0℃ |
Kuyazwela | Kuyazwela emoyeni |
Ukuncibilika | I-Soluble ku-Methanol |
Isikhathi Sokugcina. | Ivalwe Komile, Isitolo Emazingeni Okushisa Egumbi |
I-COA ne-MSDS | Iyatholakala |
Ukwahlukanisa | Ama-Amino Acid & Derivatives |
Ibhrendi | I-Ruifu Chemical |
Amakhodi Wengozi | C - Iyabola | I-WGK Germany | 3 |
Izitatimende Zokuphepha | 24/25 - Gwema ukuthintana nesikhumba namehlo. | Ikhodi ye-HS | 2922491990 |
Izinto | Amazinga Wokuhlola | Imiphumela |
Ukubukeka | Impushana Emhlophe Kuya Kumhlophe | Kuyavumelana |
I-Infrared Spectrometry | Ivumelana Nesakhiwo | Kuyavumelana |
Indlela Yokuhlola / Yokuhlaziya | 98.0~102.0% | 99.3% |
I-Melting Point | 200.0 ~ 220.0℃ | 214.0~216.0℃ |
Ukuzungezisa Okuthile [α]20/D | +9.0° ukuya +13.0°(C=1, CH3OH) | +12,43° |
Ukulahlekelwa Ekumisweni | <0.50% | 0.15% |
Izinsalela ekushiseni | <0.10% | 0.05% |
Insimbi (Fe) | <10ppm | <10ppm |
I-Sulfate (SO4) | <0.02% | <0.02% |
Izinsimbi Ezisindayo (Pb) | <10ppm | <10ppm |
I-Ammonium (NH4) | <0.08% | <0.08% |
I-Arsenic (As2O3) | <1ppm | <1ppm |
Isiphetho | Lo Mkhiqizo Ngokuhlola Uvumelana Nezinga Lebhizinisi | |
Ukusetshenziswa Okuyinhloko | Abalamuli Bezemithi;I-Safinamide Ephakathi |
Iphakheji: Ibhodlela eline-Fluorinated, isikhwama se-Aluminium foil, 25kg/Cardboard Drum, noma ngokwezidingo zekhasimende
Isimo Sesitoreji:Gcina ezitsheni ezivaliwe endaweni epholile, eyomile futhi engenamoya kude nezinto ezingahambelani.Vikela ekukhanyeni nakumswakama.
Indlela Yokuthenga?Sicela uxhumaneDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
Iminyaka engu-15 Yokuhlangenwe nakho?Sinesipiliyoni seminyaka engaphezu kwe-15 ekwakhiweni nasekuthumeleni kwamanye amazwe uhla olubanzi lwezinga eliphezulu lokuxhumanisa imithi noma amakhemikhali amahle.
Izimakethe Eziyinhloko?Thengisa emakethe yasekhaya, eNyakatho Melika, eYurophu, eNdiya, eKorea, eJapane, e-Australia, njll.
Izinzuzo?Ikhwalithi ephezulu, intengo ethengekayo, izinsizakalo ezichwepheshile nokusekelwa kobuchwepheshe, ukulethwa okusheshayo.
IkhwalithiIsiqiniseko?Isistimu yokulawula ikhwalithi eqinile.Imishini yobuchwepheshe yokuhlaziya ifaka i-NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, NOMA, KF, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, njll.
Amasampula?Imikhiqizo eminingi inikeza amasampula wamahhala wokuhlolwa kwekhwalithi, izindleko zokuthumela kufanele zikhokhelwe amakhasimende.
Ukuhlolwa Kwemboni?Wamukelekile ekucwaningweni kwemboni.Sicela wenze i-aphoyintimenti kusengaphambili.
I-MOQ?Ayikho i-MOQ.I-oda elincane liyamukeleka.
Isikhathi sokuthumela? Uma kungaphakathi kwesitoko, ukulethwa kwezinsuku ezintathu kuqinisekisiwe.
Ezokuthutha?By Express (FedEx, DHL), by Air, by Sea.
Amadokhumenti?Ngemuva kwenkonzo yokuthengisa: I-COA, i-MOA, i-ROS, i-MSDS, njll.
Custom Synthesis?Ingahlinzeka ngezinsizakalo zokwenziwa ngokwezifiso ukuze zilingane kangcono nezidingo zakho zocwaningo.
Imigomo Yokukhokha?I-invoyisi ye-Proforma izothunyelwa kuqala ngemva kokuqinisekiswa kwe-oda, kufakwe nemininingwane yethu yasebhange.Inkokhelo nge-T/T (Telex Transfer), PayPal, Western Union, njll.
I-L-Alaninamide Hydrochloride (H-Ala-NH2 · HCl) (CAS: 33208-99-0) isetshenziswa njengama-intermediate emithi.I-L-Alaninamide Hydrochloride isetshenziselwa ukulungiswa kokuphuma kwenoveli kwe-amide yezinhlanganisela ze-steroidal[3,2-c]pyrazole ezinomsebenzi weglucocorticoid.I-L-Alaninamide Hydrochloride iphakathi kwe-Safinamide (CAS: 133865-89-1) kanye ne-Safinamide Mesylate (CAS: 202825-46-5).I-Safinamide iyi-inhibitor ekhethayo neshintshayo ye-monoamine oxidase B (MAO-B, IC50=98 nM enokukhetha okungaphezu kokuphindwe ka-100 ngaphezu kwe-MAO-A. Ibonisa umsebenzi we-anticonvulsant futhi ivikele ekubanjweni okubangelwa yi-kainate kanye ne-hippocampal neurodegeneration kumamodeli wamagundane. Ukusayinda okusebenzayo kwe-glutamatergic ngokuvinjelwa kwesiteshi se-sodium okuncike ekusetshenzisweni. Ukwelapha okunoveli kwesifo sika-Parkinson okunezindlela eziningi zokwenza. Kusebenza njengesengezo ku-dopamine agonist therapy ekuqaleni kuka-Parkinson. I-Sanamide methanesulfonate yagunyazwa ngo-February 2015 yi-EMA ukuze zelashwe Isifo sikaParkinson esishintshashintshayo phakathi nesigaba sekwephuzile.Lokhu kugunyazwa kuhlanganisa ukusetshenziswa komuthi njengesengezo sokwelashwa ukuze usetshenziswe ne-Levodopa, kungaba uwedwa noma uhlanganiswe nezinye izindlela zokwelapha ezikhona ze-Parkinson's.Safinamide methanesulfonate, i-α-aminoamide yomlomo eyatholwa okokuqala nguFarmitalia Carlo Erba futhi kamuva yathuthukiswa ngu-Newron/Zambon, isebenza njenge-inhibitor ekhetha kakhulu futhi ehlehliswayo ye-MAO-B, okuholela ekwandeni kwamazinga e-dopamine kanye nokuthuthukiswa okulandelayo kwezimpawu zezimoto zesifo sikaParkinson, imiphumela engemihle evame ukuvela ukusetshenziswa kwezinye izindlela zokwelapha zendabuko ezincike ekwelashweni kokubuyisela i-dopamine.