I-L-Phenylalanine CAS 63-91-2 (H-Phe-OH) Isivivinyo 98.5~101.5% Ikhwalithi Ephezulu Yefekthri

I-L-Phenylalanine, uma yomisiwe, iqukethe okungengaphansi kuka-98.5% we-C9H11NO2.
I-L-Phenylalanine yenzeka njengamakristalu amhlophe noma i-crystalline powder.Ayinaphunga noma inephunga elincanyana, futhi inokunambitheka okubabayo kancane.Incibilika ngokukhululeka ku-formic acid, incibilika kancane emanzini, futhi ayincibiliki ku-ethanol (95).Incibilika ku-dilute hydrochloride acid.
Ukuhlonza Thola i-spectrum yokumuncwa kwe-infrared ye-L-Phenylalanine, omiswe ngaphambilini, njengoba kuqondiswe endleleni yediski ye-potassium bromide ngaphansi kwe-Infrared Spectrophotometry <2.25>, bese uqhathanisa i-spectrum ne-Reference Spectrum: zombili i-spectra zibonisa amandla afanayo okumunca ezinombolweni zamagagasi afanayo. .
I-Optical Rotation <2.49> [a]D20: -33.0° kuya -35.59° (emva kokomisa, 0.5 g, amanzi, 25 mL, 100 mm).
pH <2.54> Chaza u-0.20 g we-L-Phenylalanine ku-20 mL wamanzi: i-pH yalesi sixazululo iphakathi kuka-5.3 no-6.3
Ukuhlanzeka (1) Ukucaca kanye nombala wesixazululo-Chaza u-0.5 g we-L-Phenylalanine ku-10 mL we-1 mol hydrochloric acid TS: isixazululo sicacile futhi asinambala.
(2) I-Chloride <1.03>-Yenza ukuhlolwa ngo-0.5 g we-L-Phenylalanine.Lungiselela ikhambi lokulawula ngo-0.30 mL we-0.01 mol/L hydrochloride acid VS (hhayi ngaphezu kuka-0.021%).
(3) I-Sulfate <1.14>-Yenza ukuhlolwa ngo-0.6 g we-L-Phenylalanine.Lungiselela ikhambi lokulawula ngo-0.35 mL ka-0.005 mol/L sulfuric acid VS (hhayi ngaphezu kuka-0.028z).
(4) I-Ammonium <1.02>-Yenza ukuhlolwa ngo-0.25 g we-L-Phenylalanine.Lungiselela ikhambi lokulawula ngo-5.0 mL we-Standard Ammonium Solution (hhayi ngaphezu kuka-0.02%).
(5) I-Heavy Metals <1.07>-Chaza u-1.0 g we-L-Phenylalanine ku-40 mL wamanzi kanye no-2 mL we-acetic acid ehlanjululwayo ngokufudumeza, ukupholisa, futhi wengeze amanzi ukuze wenze u-50 mL.Yenza ukuhlolwa usebenzisa lesi sixazululo njengesixazululo sokuhlola.Lungiselela ikhambi lokulawula ngale ndlela elandelayo: ku-2.0 mL Wesixazululo Esijwayelekile Sokuhola engeza u-2 mL we-acetic acid ehlanjululwe namanzi ukuze wenze u-50 mL (hhayi ngaphezu kuka-20 ppm).
(6) I-Arsenic <1.11>-Chaza u-1.0 g we-L-Phenylalanine ku-5 mL we-dilute hydrochloride acid kanye no-15 mL wamanzi, futhi wenze ukuhlolwa ngalesi sixazululo njengesixazululo sokuhlola (hhayi ngaphezu kuka-2 ppm).
(7) Izinto Ezihlobene-Chaza u-0.10 g we-L-Phenylalanine ku-25 ml wamanzi, futhi usebenzise lesi sixazululo njengesampula yesixazululo.Ipayipi elingu-1 mL lesixazululo sesampula, bese wengeza amanzi ukwenza u-50 mL ncamashi.Pipe u-5 ml walesi sixazululo, engeza amanzi ukuze wenze ama-mL angu-20, bese usebenzisa lesi sixazululo njengesixazululo esijwayelekile.Yenza ukuhlolwa ngalezi zixazululo njengoba kuqondiswe ngaphansi kwe-Thin-layer Chromatography <2.03>.Faka i-5mL ngayinye yesixazululo sesampula kanye nesisombululo esijwayelekile epuletini lejeli ye-silica yechromatography yongqimba oluncane.Yakha ipuleti ngengxube ye-1-butanol, amanzi ne-acetic acid (100) (3:1:1) iye ebangeni elingu-10 cm, bese womisa ipuleti ku-809Cfor30minutes.Fafaza ngokulinganayo isixazululo se-ninhydrin ku-acetone (1 in50) epuletini, bese ushisisa ku-80℃ imizuzu emi-5: amachashaza ngaphandle kwendawo eyinhloko evela kusixazululo sesampula awashubi kakhulu kunendawo evela esixazululweni esijwayelekile.
Ukulahlekelwa Ekumisweni <2.41> Hhayi ngaphezulu kuka-0.30% (1 g, 105℃, amahora angu-3).
Insalela Ekuthutheni <2.44> Ayidluli ku-0.10% (1 g).
I-Assay Kala ngokunembile cishe u-0.17 g we-L-Phenylalanine, omisiwe ngaphambilini, futhi uncibilike ku-3 mL we-formic acid, engeza u-50mL we-acetic acid (100), kanye ne-titrate <2.50> nge-0.1 mol/L perchloric acid VS (potentiometric titration).Yenza isinqumo esingenalutho, futhi wenze noma yikuphi ukulungisa okudingekayo.
I-mL ngayinye ka-0.1 mol/L perchloric acid VS＝16.52 mg ye-C9H11NO2
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