I-L-Proline CAS 147-85-3 (H-Pro-OH) Isivivinyo 98.5~101.0% Ifektri Yekhwalithi Ephezulu
I-Shanghai Ruifu Chemical Co., Ltd. ingumkhiqizi oholayo nomphakeli we-L-Proline (H-Pro-OH; Isifinyezo se-Pro noma i-P) (i-CAS: 147-85-3) enekhwalithi ephezulu, amandla okukhiqiza angu-2000 Amathani ngonyaka.Njengomunye wabahlinzeki abakhulu bama-amino acid e-China, i-Ruifu Chemical ihlinzeka ngama-amino acid afika kumazinga omhlaba, njenge-AJI, USP, EP, JP kanye namazinga e-FCC.Singahlinzeka nge-COA, ukulethwa komhlaba wonke, amanani amancane kanye nenqwaba etholakalayo.Uma unentshisekelo ku-L-Proline,Please contact: alvin@ruifuchem.com
| Igama Lekhemikhali | I-L-Proline |
| Omqondofana | H-Pro-OH;L-(-)-Proline;I-L-Pro;Isifinyezo se-Pro noma i-P;I-Laevo-Proline;I-Proline;(-)-Proline;(S)-(-)-Proline;(S)-Proline;(S)-Pyrrolidine-2-Carboxylic Acid;(S)-2-Pyrrolidinecarboxylic Acid;(-)-2-Pyrrolidinecarboxylic Acid;I-L-Pyrrolidine-2-Carboxylic Acid;I-L-α-Pyrrolidinecarboxylic Acid;(S)-2-Carboxypyrrolidine |
| Isimo Sesitoko | Esitokweni, Amandla Okukhiqiza Amathani angu-2000 ngonyaka |
| Inombolo ye-CAS | 147-85-3 |
| I-Molecular Formula | I-C5H9NO2 |
| Isisindo samangqamuzana | 115.13 |
| I-Melting Point | 228℃(dec.) (lit.) |
| Ukuminyana | 1.35 |
| Kuyazwela | I-Hygroscopic |
| Ukuncibilika kwamanzi | Incibilika Emanzini, i-H2O: 50 mg/mL, Icishe Ikhanye |
| Ukuncibilika | I-Soluble Freely ku-Glacial Acetic Acid, I-Sparing Soluble ku-Ethanol.Ayincibiliki ku-Ether |
| Isikhathi Sokugcina. | Ivalwe Komile, Isitolo Emazingeni Okushisa Egumbi |
| I-COA ne-MSDS | Iyatholakala |
| Ukwahlukanisa | Ama-Amino Acids |
| Ibhrendi | I-Ruifu Chemical |
| Amakhodi Wengozi | Xi,Xn |
| Izitatimende Zobungozi | R36/37/38 - Ukucasula amehlo, uhlelo lokuphefumula kanye nesikhumba. R22 - Iyingozi uma igwinywe |
| Izitatimende Zokuphepha | I-S24/25 - Gwema ukuthintana nesikhumba namehlo. I-S36/37/39 - Gqoka izingubo zokuzivikela ezifanele, amagilavu nokuvikela iso/ubuso. S26 - Uma uthintana namehlo, geza ngokushesha ngamanzi amaningi futhi ufune iseluleko sezokwelapha. |
| I-WGK Germany | 3 |
| I-RTECS | TW3584000 |
| F | 3-10 |
| I-TSCA | Yebo |
| Ikhodi ye-HS | 2933990099 |
| Izinto | Amazinga Wokuhlola | Imiphumela |
| Ukubukeka | Amakristalu amhlophe noma i-Crystalline Powder;Ukunambitheka Kamnandi Kancane | Kuyavumelana |
| Ukuhlonza | I-Infrared Absorption Spectrum | Kuyavumelana |
| Ukuzungezisa Okuthile [α]20/D | -84.5° ukuya -86.0° (Isampula Eyomisiwe, C=4, H2O) | -85.51° |
| Isimo Sesixazululo (I-Transmittance) | Icacile futhi Ayinambala ≥98.0% | 98.5% |
| I-Chloride (Cl) | ≤0.020% | <0.020% |
| I-Sulfate (SO4) | ≤0.020% | <0.020% |
| I-Ammonium (NH4) | ≤0.020% | <0.020% |
| Insimbi (Fe) | ≤10ppm | <10ppm |
| Izinsimbi Ezisindayo (Pb) | ≤10ppm | <10ppm |
| I-Arsenic (As2O3) | ≤1.0ppm | <1.0ppm |
| Amanye ama-Amino Acids | I-Chromatographically Ayitholakali | Kuyavumelana |
| Ukulahlekelwa Ekumisweni | ≤0.30% (ku-105℃ amahora angu-3) | 0.16% |
| Izinsalela ekushiseni (Sulfated) | ≤0.10% | 0.07% |
| Isivivinyo | 98.5 kuya ku-101.0% (I-Titration, njengesisekelo Esomile) | 99.7% |
| Ukuhlolwa kwe-pH | 5.9 kuya ku-6.9 (1.0g ku-10ml ye-H2O) | 6.2 |
| I-Ninhydrin-Positive Substances | Kuyavumelana | Kuyavumelana |
| Umsuka | Kusuka Emthonjeni Ongesona Isilwane | Kuyavumelana |
| Izincibilikisi Ezisele | Kuyavumelana | Kuyavumelana |
| Isiphetho | Ihlangana no-AJI97;EP;USP;I-JP Testing Specifications | |
| Ukusetshenziswa Okuyinhloko | Ama-amino Acids;Izithasiselo Zokudla;Ezemithi;Isengezo Sokudla Okunomsoco | |
I-L-Proline (H-Pro-OH) (CAS: 147-85-3) Indlela Yokuhlola ye-AJI 97
Ukuhlonza: Qhathanisa i-spectrum yokumuncwa kwe-infrared yesampula naleyo yezinga lendlela ye-potassium bromide disc.
Ukuzungezisa Okuthile [α]20/D: Isampula Eyomisiwe, C=4, H2O
Isimo Sesixazululo (Ukudlulisa): 1.0g ku-10ml we-H2O, i-spectrophotometer, 430nm, 10mm ubukhulu beseli.
I-Chloride (Cl): 0.7g, A-1, ref: 0.40ml ka-0.01mol/L HCl
I-Ammonium (NH4): B-1
I-Sulfate (SO4): 1.2g, (1), ref: 0.50ml ka-0.005mol/L H2SO4
I-ayoni (Fe): 1.5g, ref: 1.5ml ye-Iron Std.(0.01mg/ml)
Izinsimbi Ezisindayo (Pb): 2.0g, (1), ref: 2.0ml ye-Pb Std.(0.01mg/ml)
I-Arsenic (As2O3): 2.0g, (1), ref: 2.0ml ye-As2O3 Std.
Amanye ama-Amino Acid: Isampula Yokuhlola: 30μg, B-6-a
Ukulahlekelwa Ekumisweni: ku-105 ℃ amahora angu-3.
I-Assay: Isampula eyomisiwe, 120mg, (1), 3ml ye-formic acid, 50ml ye-glacial acetic acid, 0.1mol/L HCLO4 1ml=11.513mg C5H9NO2
Ukuhlolwa kwe-pH: 1.0g ku-10ml ye-H2O
I-L-Proline (H-Pro-OH) (CAS: 147-85-3) Indlela Yokuhlola ye-USP35
INCAZELO
I-Proline iqukethe i-NLT 98.5% kanye ne-NMT 101.5% ye-L-Proline (C5H9NO2), abalwe ngokomisiwe.
UKUKHOMBA
A. UKUMUMVA OKUTHI INFRARED <197K>
ISIVIVINYO
INQUBO
Isampula: 110 mg yeProline
Okungenalutho: Hlanganisa u-3 mL we-formic acid no-50 mL we-glacial acetic acid.
Isistimu ye-Titrimetric
(Bheka i-Titrimetry <541>)
Imodi: I-titration eqondile
I-Titrant: 0.1 N i-perchloric acid VS
Ukutholwa kwendawo yokugcina: I-Potentiometric
Ukuhlaziya: Chaza Isampula ku-3 mL we-formic acid kanye no-50mL we-glacial acetic acid.Titrate nge-Titrant.Yenza ukuzimisela Okungenalutho.
Bala iphesenti le-Proline (C5H9NO2) kuSampuli ethathiwe:
Umphumela = {[(VS-VB) x N x F]/W} x100
VS= ivolumu ye-Titrant esetshenziswe Isampula (mL)
I-VB= ivolumu ye-Titrant edliwe yi-Blank (mL)
N= ukujwayelekile kwangempela kwe-Titrant (mEq/mL)
F= i-equivalency factor, 115.1 mg/mEq
W= Isisindo sesampula (mg)
Indlela yokwamukela: 98.5%~101.5% ngokomisiwe
UKUNGCOLA
ISAZISO EKUSHIYENI <281>: NMT 0.4%
I-CHLORIDE NE-SULFATE, I-Chloride <221>
Isixazululo esijwayelekile: 0.50mL ka-0.020 N hydrochloric acid
Isampula: 0.73g ye-Proline
Indlela yokwamukela: NMT 0.05%
I-CHLORIDE NE-SULFATE, i-Sulfate <221>
Isixazululo esijwayelekile: 0.10mL ka-0.020 N sulfuric acid
Isampula: 0.33g ye-Proline
Indlela yokwamukela: NMT 0.03%
I-IRON <241>: NMT 30ppm
IZINSIMBI EZINZIMA, Indlela I <231>: NMT 15ppm
AMACOMPOUNDS AMAQINISO
Isixazululo sokufaneleka kwesistimu: 0.4mg/mL ngayinye ye-USP L-Proline RS kanye ne-USP L-Threonine RS ku-0.1 N hydrochloric acid
Isixazululo esijwayelekile: 0.05mg/mL ye-USP L-Proline RS ku-0.1 N hydrochloric acid.[QAPHELA-Lesi sixazululo sinokugxila okulingana no-0.5% wesixazululo Sesampuli.]
Isixazululo sesampula: 10mg/mL ye-Proline ku-0.1 N hydrochloric acid
Isistimu yeChromatographic
(Bona i-Chromatography <621>, I-Thin-Layer Chromatography.)
Imodi: TLC
I-Adsorbent: 0.25-mm ungqimba lwengxube yejeli yesilica yechromatographic
Ivolumu yohlelo lokusebenza: 5μL
Ukuthuthukisa uhlelo lokuncibilikisa: I-Butyl alcohol, i-glacial acetic acid, namanzi (3:1:1)
I-reagent yokufutha: 2 mg/mL we-ninhydrin kwingxube ye-butyl alcohol ne-2N acetic acid (95:5)
Ukufaneleka kwesistimu
Izidingo zokufaneleka: Ichromatogram yesisombululo sokufaneleka Kwesistimu ibonisa izindawo ezimbili ezihlukene ngokusobala.
Ukuhlaziya
Amasampula: Isixazululo sokufaneleka kwesistimu, isixazululo esijwayelekile, kanye nesixazululo sesampula.
Ngemva kokumisa ipuleti ngomoya, fafaza nge-Spray reagent, bese ushisa phakathi kuka-100° no-105° imizuzu engu-15.Hlola ipuleti ngaphansi kokukhanya okumhlophe.
Imibandela yokwamukela: Noma iyiphi indawo yesibili yesisombululo Sesampuli ayinkulu noma iqine kakhulu kunendawo eyinhloko yesisombululo Esivamile.
Ukungcola komuntu ngamunye: NMT 0.5%
Ukungcola okuphelele: NMT 2.0%
IZIVIVINYO EZITHILE
UKUZUNGUZA KOMBONISO, Ukuzungezisa Okuqondile <781S>
Isixazululo sesampula: 40 mg/mL emanzini
Imibandela yokwamukela: -84.3° ukuya -86.3°
I-LASSON DRYING <731>: Yomisa isampula ku-105℃ amahora angu-3: ilahlekelwa yi-NMT 0.4% yesisindo sayo.
IZIDINGO EZENGEZIWE
UKUPAKASHA KANYE NESIGCINI: Londoloza ezitsheni ezivalwe kahle.
I-USP REFERENCE AMAZINGA <11>
I-USP L-Proline RS
I-USP L-Threonine RS
Iphakheji: Ibhodlela eliFluorinated, 25kg/bag, 25kg/Cardboard Drum, noma ngokwezidingo zekhasimende.
Isimo Sesitoreji:I-Hygroscopic.Gcina ezitsheni ezivaliwe endaweni epholile, eyomile futhi engenamoya kude nezinto ezingahambelani.Vikela ekukhanyeni nakumswakama.Akuhambisani nama-oxidizing agents aqinile.
Indlela Yokuthenga?Sicela uxhumaneDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
Iminyaka engu-15 Yokuhlangenwe nakho?Sinesipiliyoni seminyaka engaphezu kwe-15 ekwakhiweni nasekuthumeleni kwamanye amazwe uhla olubanzi lwezinga eliphezulu lokuxhumanisa imithi noma amakhemikhali amahle.
Izimakethe Eziyinhloko?Thengisa emakethe yasekhaya, eNyakatho Melika, eYurophu, eNdiya, eKorea, eJapane, e-Australia, njll.
Izinzuzo?Ikhwalithi ephezulu, intengo ethengekayo, izinsizakalo ezichwepheshile nokusekelwa kobuchwepheshe, ukulethwa okusheshayo.
IkhwalithiIsiqiniseko?Isistimu yokulawula ikhwalithi eqinile.Imishini yobuchwepheshe yokuhlaziya ifaka i-NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, NOMA, KF, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, njll.
Amasampula?Imikhiqizo eminingi inikeza amasampula wamahhala wokuhlolwa kwekhwalithi, izindleko zokuthumela kufanele zikhokhelwe amakhasimende.
Ukuhlolwa Kwemboni?Wamukelekile ekucwaningweni kwemboni.Sicela wenze i-aphoyintimenti kusengaphambili.
I-MOQ?Ayikho i-MOQ.I-oda elincane liyamukeleka.
Isikhathi sokuthumela? Uma kungaphakathi kwesitoko, ukulethwa kwezinsuku ezintathu kuqinisekisiwe.
Ezokuthutha?By Express (FedEx, DHL), by Air, by Sea.
Amadokhumenti?Ngemuva kwenkonzo yokuthengisa: I-COA, i-MOA, i-ROS, i-MSDS, njll.
Custom Synthesis?Ingahlinzeka ngezinsizakalo zokwenziwa ngokwezifiso ukuze zilingane kangcono nezidingo zakho zocwaningo.
Imigomo Yokukhokha?I-invoyisi ye-Proforma izothunyelwa kuqala ngemva kokuqinisekiswa kwe-oda, kufakwe nemininingwane yethu yasebhange.Inkokhelo nge-T/T (Telex Transfer), PayPal, Western Union, njll.
I-L-Proline (H-Pro-OH; Isifinyezo se-Pro noma i-P) (i-CAS: i-147-85-3) i-amino acid engathathi hlangothi.Nakuba i-proline ihlukaniswa njenge-amino acid, ikhuluma ngokuqinile i-imino acid, njengoba iqukethe iqembu le-imino (i-carbon-nitrogen double bond).Ngenxa ye-cyclic pyrrolidine side chain ihlukaniswa njenge-nonpolar aliphatic amino acid.
Isicelo
Isetshenziswa ocwaningweni lwamakhemikhali ezinto eziphilayo, umuthi wokungondleki, ukuntuleka kwamaprotheni, izifo zesisu, i-scald kanye nesengezo sephrotheni sangemva kokuhlinzwa.
1. Njenge-amino acid, ingeza imisoco futhi iyimpahla eluhlaza yokufakwa kwe-amino acid.
2. Isebenza ngempumelelo ku-hypertension futhi iyingxenye ebalulekile yokuhlanganiswa kwezidakamizwa zomugqa wokuqala we-antihypertensive njenge-captopril ne-enalapril.
3. Njengesengezo sokudla okunomsoco, kungathuthukisa ukumelana nezicubu futhi kwandise izinga lokusinda kwe-callus.Ama-flavour nge-sugar fever kwenzeka ukusabela kwe-amino-carbonyl, kungakhiqiza izinto ezikhethekile zokunambitheka.I-China GB 2760-86 inikeza ingasetshenziswa njengesinongo.
4. Inganciphisa ngokuphumelelayo umonakalo wokucindezeleka kukasawoti esakhiweni se-mitochondrial sezitshalo ezivuselelwe irayisi.
5. I-L-Proline iyi-amino acid engabalulekile.Ama-Peptides abopha i-proline, okwenza kube isisekelo esiwusizo sokwakha amaprotheni.Ingasetshenziswa njengengxenye yemidiya yesiko lamaseli ekwenzeni i-biomanufacturing yezentengiselwano yamaphrotheni ahlanganisayo okwelapha kanye namasosha omzimba e-monoclonal.
6. I-L-Proline isetshenziswa njengama-catalysts asymmetric ku-organic synthesis kanye ne-asymmetric aldol cyclization.Kuyingxenye esebenzayo ye-collagen futhi ehilelekile ekusebenzeni kahle kwamalunga nama-tendon.Ithola ukusetshenziswa kwezemithi, izinhlelo zokusebenza ze-biotechnological ngenxa yendawo yayo ye-osmoprotectant.
Umsebenzi:
1. I-L-Proline kanye nokuphuma kwayo kuvame ukusetshenziswa njengama-catalysts asymmetric ekuphenduleni kwezinto eziphilayo.Ukwehliswa kwe-CBS kanye ne-proline catalysed aldol condensation yizibonelo ezivelele.
2. I-L-Proline iyi-osmoprotectant ngakho-ke isetshenziswa emikhakheni eminingi, izinhlelo zokusebenza ze-biotechnological.Ekuphekweni, amaprotheni anothe nge-proline ahlangana nama-polyphenols ukuze akhiqize inkungu.
3. I-L-Proline ingenye yama-amino acid abalulekile ekuhlanganiseni amaprotheni abantu.Isetshenziswa kabanzi embonini yezokudla nezokwelapha, futhi iyindawo ebalulekile yokuhlanganiswa kwe-ACE inhibitors njenge-Captopril ne-Enalapril.Futhi kungenye yezinto ezibalulekile zokusetshenziswa kokumpontshelwa kwe-amino acid.
4. I-L-Proline isetshenziswe emhlabeni wonke njengesengezo sokudla, i-catalyst kanye nezinto zokusetshenziswa zemboni yamakhemikhali emihle.
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