I-L-Serine CAS 56-45-1 (H-Ser-OH) Isivivinyo 98.5~101.0% Ifektri Yekhwalithi Ephezulu
I-Shanghai Ruifu Chemical Co., Ltd. ingumnikezeli ohamba phambili we-L-Serine (H-Ser-OH; I-Ser efushanisiwe noma i-S) (i-CAS: 56-45-1) enekhwalithi ephezulu.Njengomunye wabahlinzeki abakhulu bama-amino acid e-China, i-Ruifu Chemical ihlinzeka ngama-amino acid ahlangabezana namazinga e-AJI, i-USP, i-EP, i-JP ne-FCC.Singahlinzeka nge-COA, ukulethwa komhlaba wonke, amanani amancane kanye nenqwaba etholakalayo.Uma unentshisekelo ku-L-Serine,Please contact: alvin@ruifuchem.com
| Igama Lekhemikhali | I-L-Serine |
| Omqondofana | H-Ser-OH;L-Ser;I-Ser efinyeziwe noma u-S;(-)-Serine;I-Serine;I-Laevo-Serine;(S)-Serine;I-L-2-Amino-3-Hydroxypropionic Acid;(S) -2-Amino-3-Hydroxypropionic Acid;(S) -α-Amino-β-Hydroxypropionic Acid;I-L-3-Hydroxy-2-Aminopropionic Acid;I-3-Hydroxy-L-Alanine;I-β-Hydroxy-L-Alanine |
| Isimo Sesitoko | Esitokweni, Amandla Okukhiqiza Amathani angama-500 ngonyaka |
| Inombolo ye-CAS | 56-45-1 |
| I-Molecular Formula | C3H7NO3 |
| Isisindo samangqamuzana | 105.09 |
| I-Melting Point | 222℃(dec.) (lit.) |
| Ukuminyana | 1.6 |
| Ukuncibilika kwamanzi | Incibilika Emanzini, Icishe Ikhanye |
| Ukuncibilika | Incibilika Ngokukhululekile ku-Formic Acid.Ayincibiliki ku-Ethanol naku-Ether.Incibilika ku-Dilute Hydrochloric Acid |
| Isikhathi Sokugcina. | Ivalwe Komile, Isitolo Emazingeni Okushisa Egumbi |
| I-COA ne-MSDS | Iyatholakala |
| Ukwahlukanisa | Ama-Amino Acid & Derivatives |
| Ibhrendi | I-Ruifu Chemical |
| Izinto | Amazinga Wokuhlola | Imiphumela |
| Ukubukeka | Amakristalu Amhlophe noma I-Crystalline Powder | Kuyavumelana |
| Ukuhlonza | I-Infrared Absorption Spectrum | Kuyavumelana |
| Ukuzungezisa Okuthile [α]20/D | +14.4° ukuya +15.5° (C=10, 2N HCl) | -33.8° |
| Isimo Sesixazululo (I-Transmittance) | Icacile futhi Ayinambala ≥98.0% | 98.6% |
| I-Chloride (Cl) | ≤0.020% | <0.020% |
| I-Sulfate (SO4) | ≤0.020% | <0.020% |
| I-Ammonium (NH4) | ≤0.020% | <0.020% |
| Insimbi (Fe) | ≤10ppm | <10ppm |
| Izinsimbi Ezisindayo (Pb) | ≤10ppm | <10ppm |
| I-Arsenic (As2O3) | ≤1.0ppm | <1.0ppm |
| Amanye ama-Amino Acids | I-Chromatographically Ayitholakali | Kuyavumelana |
| Ukulahlekelwa Ekumisweni | ≤0.20% (ku-105℃, amahora angu-3) | 0.15% |
| Izinsalela ekushiseni (Sulfated) | ≤0.10% | 0.06% |
| Isivivinyo | 98.5 kuya ku-101.0% (Titration: Isisekelo Esomisiwe) | 99.7% |
| Ukuhlolwa kwe-pH | 5.2 kuya ku-6.2 (1.0g ku-10ml we-H2O) | 5.5 |
| Ukungcola Okuguquguqukayo Kwezinto Eziphilayo | Ihlangabezana Nezimfuneko | Kuyavumelana |
| Umsuka | Umthombo Ongewona Wesilwane | Kuyavumelana |
| Izincibilikisi Ezisele | Kuyavumelana | Kuyavumelana |
| Isiphetho | Ihlangabezana ne-AJI97, EP, USP, JP Ukucaciswa Kokuhlola | |
| I-Shelf Life | Izinyanga ezingama-24 Kusuka Kudethi Yokukhiqiza Uma Igcinwe Ngokufanelekile | |
| Ukusetshenziswa Okuyinhloko | Izithasiselo Zokudla;Ezemithi;Isengezo Sokudla Okunomsoco;njll. | |
Iphakheji: Ibhodlela eliFluorinated, 25kg/bag, 25kg/Cardboard Drum, noma ngokwezidingo zekhasimende.
Isimo Sesitoreji:Gcina ezitsheni ezivaliwe endaweni epholile, eyomile futhi engenamoya kude nezinto ezingahambelani.Vikela ekukhanyeni nakumswakama.
JP16
I-L-Serine, uma yomisiwe, iqukethe okungaphansi kuka-98.5% futhi hhayi ngaphezu kuka-101.0% we-C3H7NO3.
I-L-Serine yenzeka njengamakristalu amhlophe noma i-crystalline powder.Inokunambitheka okumnandi okuncane.Incibilika ngokukhululeka emanzini naku-asidi ye-formic, futhi ayincibiliki ku-ethanol (99.5).Incibilika ku-2 mol/L hydrochloric acid TS.
Ukuhlonza Thola i-spectrum yokumuncwa kwe-infrared ye-L-Serine njengoba kuqondiswe endleleni yediski ye-potassium bromide ngaphansi kwe-Infrared Spectrophotometry<2.25>, bese uqhathanisa i-spectrum ne-Reference Spectrum: yomibili i-spectra ibonisa ukuqina okufanayo kokumuncwa ezinombolweni zamagagasi afanayo.
Ukuzungezisa kwamehlo <2.49> [a]20D: +14.0°~+16.0°(Ngemva kokomisa, 2.5 g, 2 mol/L hydrochloric acid TS, 25 mL, 100 mm).
I-pH <2.54> I-pH yesisombululo esilungiswe ngokuncibilikisa u-1.0 g we-L-Serine ku-10 mL wamanzi iphakathi kuka-5.2 no-6.2.
Ukuhlanzeka (1) Ukucaca kanye nombala wesixazululo-Diza i-1.0 g ye-L-Serine ku-10 mL wamanzi: isixazululo sicacile futhi asinambala.
(2) I-Chloride <1.03>-Yenza ukuhlolwa ngo-0.5 g we-L-Serine.Lungiselela ikhambi lokulawula ngo-0.30 mL we-0.01mol/L hydrochloric acid VS (hhayi ngaphezu kuka-0.021%)
(3) I-sulfate <1.14> Yenza ukuhlolwa nge-0.6 g ye-L-Serine.Lungiselela ikhambi lokulawula ngo-0.35 mL we-0.005mol/L sulfuric acid VS (hhayi ngaphezu kuka-0.028%).
(4) I-Ammonium <1.02>-Yenza ukuhlolwa ngo-0.25 g we-L-Serine.Lungiselela ikhambi lokulawula ngo-5.0 mL we-Standard Ammonium Solution (hhayi ngaphezu kuka-0.02%).
(5) Izinsimbi Ezisindayo <1.07> Qhubeka no-2.0 g we-L-Serine ngokweNdlela 1, futhi wenze ukuhlolwa.Lungiselela isixazululo sokulawula ngo-2.0 mL we-Standard lead Solution (hhayi ngaphezu kuka-10 ppm).
6 .
(7) Izinto Ezihlobene-Chaza u-0.10 g we-L-Serine ku-10mL wamanzi, futhi usebenzise lesi sixazululo njengesixazululo sesampula.Ipayipi elingu-1 mL lesixazululo sesampula, engeza amanzi ukwenza u-10 mL ngqo.Ipayipi elingu-1 mL lalesi sixazululo, engeza amanzi ukwenza u-50 mL ngqo, futhi usebenzise lesi sixazululo njengesixazululo esijwayelekile.Yenza ukuhlola ngalezi zixazululo njengoba uqondiswe ngaphansi kwe-Thin-layer Chromatography<2.03>.I-Spot 5mLeachofthesampuli yesixazululo nesixazululo esijwayelekile epuletini lejeli ye-silica forthin-layer chromatography.Bese uthuthukisa ngengxube ye-1-butanol, amanzi ne-acetic acid (100) (3:1:1) ukuya ebangeni elingaba ngu-10 cm, bese usula ipuleti ku-809C imizuzu engama-30.Isixazululo se-sprayevenly se-ninhydrinin ingxube ye-methanol andacetic acid (100) (97:3) (1 ku-100) epuletini, nokushisa ku-80℃ imizuzu engu-10: indawo ngaphandle kwendawo eyinhloko etholwe esixazululweni sesampula ayikho. kuqine kakhulu kunendawo evela kusixazululo esijwayelekile.
Ukulahlekelwa Ekumisweni <2.41> Hhayi ngaphezulu kuka-0.3%(1 g, 105℃, amahora angu-3).
Insalela Ekushiseni <2.44> Ayidluli ku-0.1%(1 g).
I-Assay Kala ngokunembile cishe u-0.11 g we-L-Serine, omisiwe ngaphambilini, ncibilika ku-3 mL we-formic acid, engeza u-50 mL we-acetic acid (100), kanye ne-titrate engu-<2.50> ngo-0.1 mol/L perchloric acid VS (i-potentiometric titration).Yenza isinqumo esingenalutho ngendlela efanayo, futhi wenze noma yikuphi ukulungisa okudingekayo.
I-mL ngayinye ka-0.1 mol/L i-perchloric acid VS＝10.51 mg ye-C3H7NO3
Iziqukathi nokugcina Iziqukathi-Tight iziqukathi.
I-USP39-NF34
INCAZELO L-Serine iqukethe i-NLT 98.5% kanye ne-NMT 101.5% ye-L-serine (C3H7NO3), ebalwa ngokomiswa.
UKUKHOMBA
A. UKUMUMVA OKUTHI INFRARED <197K>
ISIVIVINYO
INQUBO
Isampula: 100mg ye-Serine
Okungenalutho: Hlanganisa u-3mL we-formic acid no-50mL we-glacial acetic acid.
Isistimu ye-Titrimetric
(Bheka i-Titrimetry <541>)
Imodi: I-titration eqondile
I-Titrant: 0.1 N i-perchloric acid VS
Ukutholwa kwendawo yokugcina: I-Potentiometric
Ukuhlaziya: Chaza Isampula ku-3mL we-formic acid kanye no-50mL we-glacial acetic acid.Titrate nge-Titrant.
Yenza ukuzimisela Okungenalutho.
Bala iphesenti le-serine (C3H7NO3) kusampula elithathiwe:
Umphumela = {[(VS-VB) xNxF]/W} x100
VS= Ivolumu ye-Titrant esetshenziswe Isampula (mL)
VB= Ivolumu ye-Titrant edliwe yi-Blank (mL)
N= ukujwayelekile kwangempela kwe-Titrant (mEq/mL)
F= i-equivalency factor, 105.1mg/mEq
W= Isisindo sesampula (mg)
Indlela yokwamukela: 98.5%~101.5% ngokomisiwe
UKUNGCOLA
UKUSHISA OKUSELELE <281>: NMT 0.1%
I-CHLORIDEAND SULFATE, i-Chloride <221>
Isixazululo esijwayelekile: 0.50mL ka-0.020 N hydrochloric acid
Isampula: 0.73g ye-Serine
Indlela yokwamukela: NMT 0.05%
I-CHLORIDEAND SULFATE, i-Sulfate <221>
Isixazululo esijwayelekile: 0.10mL ka-0.020 N sulfuric acid
Isampula: 0.33g ye-Serine
Indlela yokwamukela: NMT 0.03%
I-IRON <241>: NMT 30ppm
Susa okulandelayo:
IZINSIMBI EZINZIMA, Indlela I <231>: NMT 15ppm (Okusemthethweni 1-Jan-201)
AMACOMPOUNDS AMAQINISO
Isixazululo sokufaneleka kwesistimu: 0.4mg/mL ngayinye ye-USP L-Serine RS ne-USP L-Methionine RS ku-0.1 N hydrochloric acid
Isixazululo esijwayelekile: 0.05mg/mL ye-USP L-Serine RS ku-0.1 N hydrochloric acid.[QAPHELA-Lesi sixazululo sinokugxila okulingana cishe no-0.5% wesixazululo Sesampuli.]
Isixazululo sesampula: 10mg/mL we-Serine ku-0.1 N hydrochloric acid
Isistimu ye-Chromatographic Bona i-Chromatography <621>, I-Thin-Layer Chromatography.)
Imodi: TLC
I-Adsorbent: 0.25-mm ungqimba lwengxube yejeli yesilica yechromatographic
Ivolumu yohlelo lokusebenza: 5μL
Ukuthuthukisa uhlelo lokuncibilikisa: I-Butyl alcohol, i-glacial acebutyl alcohol ne-2N acetic acid (95:5)
Ukufaneleka kwesistimu
Izidingo zokufaneleka: Ichromatogram yesisombululo sokufaneleka Kwesistimu ibonisa izindawo ezimbili ezihlukene ngokusobala.
Ukuhlaziya
Amasampula: Isixazululo sokufaneleka kwesistimu, isixazululo esijwayelekile, kanye nesixazululo sesampula.
Ngemva kokumisa ipuleti ngomoya, fafaza nge-Spray reagent, bese ushisa phakathi kuka-100° no-105° imizuzu engu-15.Hlola ipuleti ngaphansi kokukhanya okumhlophe.
Imibandela yokwamukela: Noma iyiphi indawo yesibili yesisombululo Sesampuli ayinkulu noma iqine kakhulu kunendawo eyinhloko yesisombululo Esivamile.
Ukungcola komuntu ngamunye: NMT 0.5%
Ukungcola okuphelele: NMT 2.0%
IZIVIVINYO EZITHILE
UKUZUNGUZA KOMBONISO, Ukuzungezisa Okuqondile <781S>
Isixazululo sesampula: 100mg/mL ku-2N hydrochloric acid
Imibandela yokwamukela: +14.0° ukuya ku-+15.6°
I-LASSON DRYING <731>: Yomisa isampula ku-105℃ amahora angu-3: ilahlekelwa yi-NMT 0.2% yesisindo sayo.
IZIDINGO EZENGEZIWE
ACKAGINGAND STORAGE: Londoloza ezitsheni ezivalwe kahle.
I-USP REFERENCE AMAZINGA <11>
I-USP L-Methionine RS
I-USP L-Serine RS
Indlela Yokuthenga?Sicela uxhumaneDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
Iminyaka engu-15 Yokuhlangenwe nakho?Sinesipiliyoni seminyaka engaphezu kwe-15 ekwakhiweni nasekuthumeleni kwamanye amazwe uhla olubanzi lwezinga eliphezulu lokuxhumanisa imithi noma amakhemikhali amahle.
Izimakethe Eziyinhloko?Thengisa emakethe yasekhaya, eNyakatho Melika, eYurophu, eNdiya, eKorea, eJapane, e-Australia, njll.
Izinzuzo?Ikhwalithi ephezulu, intengo ethengekayo, izinsizakalo ezichwepheshile nokusekelwa kobuchwepheshe, ukulethwa okusheshayo.
IkhwalithiIsiqiniseko?Isistimu yokulawula ikhwalithi eqinile.Imishini yobuchwepheshe yokuhlaziya ifaka i-NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, NOMA, KF, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, njll.
Amasampula?Imikhiqizo eminingi inikeza amasampula wamahhala wokuhlolwa kwekhwalithi, izindleko zokuthumela kufanele zikhokhelwe amakhasimende.
Ukuhlolwa Kwemboni?Wamukelekile ekucwaningweni kwemboni.Sicela wenze i-aphoyintimenti kusengaphambili.
I-MOQ?Ayikho i-MOQ.I-oda elincane liyamukeleka.
Isikhathi sokuthumela? Uma kungaphakathi kwesitoko, ukulethwa kwezinsuku ezintathu kuqinisekisiwe.
Ezokuthutha?By Express (FedEx, DHL), by Air, by Sea.
Amadokhumenti?Ngemuva kwenkonzo yokuthengisa: I-COA, i-MOA, i-ROS, i-MSDS, njll.
Custom Synthesis?Ingahlinzeka ngezinsizakalo zokwenziwa ngokwezifiso ukuze zilingane kangcono nezidingo zakho zocwaningo.
Imigomo Yokukhokha?I-invoyisi ye-Proforma izothunyelwa kuqala ngemva kokuqinisekiswa kwe-oda, kufakwe nemininingwane yethu yasebhange.Inkokhelo nge-T/T (Telex Transfer), PayPal, Western Union, njll.
| Izimpawu Eziyingozi | Xi - Iyacasula |
| Amakhodi Engozi | 36/37/38 - Ukucasula amehlo, uhlelo lokuphefumula kanye nesikhumba. |
| Incazelo Yokuphepha | I-S24/25 - Gwema ukuthintana nesikhumba namehlo. I-S36 - Gqoka izingubo ezifanele zokuzivikela. S26 - Uma uthintana namehlo, geza ngokushesha ngamanzi amaningi futhi ufune iseluleko sezokwelapha. |
| I-WGK Germany | 3 |
| I-RTECS | I-VT8100000 |
| F | 3 |
| I-TSCA | Yebo |
| Ikhodi ye-HS | 2922509099 |
I-L-Serine (H-Ser-OH; I-Ser efushanisiwe noma i-S) (i-CAS: i-56-45-1) i-amino acid, ingenye ye-proteinogenic amino acids.Ama-codon ayo kukhodi yofuzo yi-UCU, UCC, UCA, UCG, AGU kanye ne-AGC.Ngenxa yeqembu le-hydroxyl, i-serine ihlukaniswa njenge-polar amino acid.
Umsebenzi kanye nokusetshenziswa kwe-L-Serine Cas 56-45-1
1. I-L-Serine isetshenziswa njenge-reagent ye-biochemical kanye nezithasiselo zokudla;Isetshenziswa ocwaningweni lwe-biochemical, ukulungiswa kwesiko lenhlangano, umuthi osetshenziselwa ama-amino acid emuthini wokudla okunempilo.
2. I-L-Serine isetshenziswa emkhakheni wezokwelapha, i-L-Serine isetshenziswa kabanzi ukulungisa ukumnika kwe-amino acid eyinhlanganisela yesizukulwane sesithathu kanye nezithako zokudla okunomsoco, kanye nokuhlanganiswa kokuphuma kwezinhlobonhlobo ze-amino acid kasilika, njengenhliziyo, umdlavuza, ingculaza kanye nezakhi zofuzo. ubunjiniyela bemithi emisha namanye ama-amino acid avikelwe.Inkundla yokudla nesiphuzo, i-L-Serine ingasetshenziselwa iziphuzo zezemidlalo, iziphuzo zokudla zama-amino acid.Insimu yokuphakelayo, i-L-Serine ingasetshenziselwa ukudla kwezilwane, ukukhuthaza ukukhula nokuthuthuka kwezilwane;
3. I-L-Serine isetshenziswa njengesengezo Somsoco, ezimonyoni njengesithako somsoco wesikhumba.
4. Itholakalela izinjongo zocwaningo lwe-biochemical kanye nokudla okunempilo, kodwa futhi ingasetshenziswa njenge-synthetic ring serine raw materials
5. I-L-Serine inezinhlobonhlobo zokusetshenziswa kwezokwelapha.I-Serine ikhuthaza ukuguqulwa kwamafutha nama-fatty acids futhi isiza ukugcina amasosha omzimba.
6. I-L-Serine iphinde isetshenziswe njengesengezo sokudla lapho ingasiza ekuthuthukiseni ukusebenza kwenkumbulo kanye nasemikhiqizweni yokunakekelwa komuntu siqu lapho isiza khona ngokukhiqizwa kwamangqamuzana esikhumba amasha.
7. I-L-Serine isetshenziswe ekulungiseleleni i-Tris-BSAN buffer ye-homogenization.Ibuye isetshenziselwe ukuhlaziywa kwenani lokuphuma kwama-polypeptides kumchamo ojwayelekile.
8. I-L-Serine isetshenziselwa ukuhlanganiswa kwe-purines ne-pyrimidines njengama-antibacterial / antifungal agents, kanye nokusebenza njenge-proteinogenic compound.
9. I-L-Serine ihlukaniswa njenge-amino acid engabalulekile.Isetshenziswa njengengxenye yemidiya yesiko lamaseli kanye nezinto ezingavuthiwe zokwenziwa kwezentengiselwano ze-biomanufacture yamaphrotheni ahlanganisayo okwelapha kanye namasosha omzimba e-monoclonal.
10. I-L-Serine ngokusebenzisa i-phosphorylation-hydroxy derivative ingakhishwa ngemva kwemisebenzi ebalulekile ye-physiological ye-P serine ingxenye enkulu ye-phospholipids;
11. I-L-Serine enenani elizinzile le-pH yendima yamaconsi iso, amaconsi iso nokungacasuli;
12. I-L-Serine iyisici esibalulekile somswakama wemvelo (i-NMF) ingenye ye-stratum corneum yokugcina indima eyinhloko yamanzi, i-L-Serine iyisihluthulelo sezithako ezithuthukisiwe zezimonyo.
