I-L-Thyroxine CAS 51-48-9 Purity >98.0% (HPLC)
I-Shanghai Ruifu Chemical Co., Ltd. ingumkhiqizi oholayo nomphakeli we-L-Thyroxine (CAS: 51-48-9) enekhwalithi ephezulu.Singahlinzeka nge-COA, ukulethwa komhlaba wonke, amanani amancane kanye nenqwaba etholakalayo.Uma unentshisekelo kulo mkhiqizo, sicela uthumele imininingwane enemininingwane ehlanganisa inombolo ye-CAS, igama lomkhiqizo, nenani kithi.Please contact: alvin@ruifuchem.com
| Igama Lekhemikhali | I-L-Thyroxine |
| Omqondofana | Levothyroxine;I-L-T4;I-NSC 36397;(-)-Thyroxine;3,3',5,5'-Tetraiodo-L-Thyronine;3,5,3',5'-Tetraiodothyronine;i-beta-[(3,5-Diiodo-4-Hydroxyphenoxy) -3,5-Diiodophenyl]alanine;β-(3,5-Diiodo-4-Hydroxyphenoxy) -3,5-Diiodophenyl)alanine;o-(4-Hydroxy-3,5-Diiodophenyl)-3,5-Diiodo-L-Tyrosine |
| Inombolo ye-CAS | 51-48-9 |
| Inombolo yeCAT | RF2891 |
| Isimo Sesitoko | Esitokweni, Isikali Sokukhiqiza Sifinyelela Kumathani |
| I-Molecular Formula | I-C15H11I4NO4 |
| Isisindo samangqamuzana | 776.87 |
| I-Melting Point | 227.0~230.0℃ |
| Iphuzu elibilayo | 576.3±50.0℃ |
| Ukuminyana | 2.635 |
| Kuyazwela | Ukukhanya Okuzwelayo |
| Ukuncibilika kwamanzi | Ayincibiliki Emanzini |
| Ukuncibilika | Incibilika ku-4M Ammonium Hydroxide ku-Methanol ngo-50mg/ml |
| Ukuzinza | ≥ Iminyaka emi-2 |
| Ikhodi ye-HS | 29379000 |
| Ibhrendi | I-Ruifu Chemical |
| Into | Imininingwane |
| Ukubukeka | I-Crystalline Powder Emhlophe noma Engamhlophe |
| Ukuhlanzeka / Indlela Yokuhlaziya | >98.0% (HPLC) |
| I-Melting Point | 227.0~230.0℃ |
| Ukuzungezisa Okuthile [α]20/D | -5.2°~ -6.2° (C=1, i-Ethanol: 1N NaOH=2:1) |
| Izinsimbi Ezisindayo (Pb) | ≤10ppm |
| Ukulahlekelwa Ekumisweni | <0.20% |
| Izinsalela ekushiseni | <0.10% |
| Ukungcola Okuphelele | <1.50% |
| I-Infrared Spectrum | Ivumelana Nesakhiwo |
| Izinga Lokuhlola | I-Enterprise Standard |
| Ukusetshenziswa | Pharmaceutical Intermediates |
Iphakheji: Ibhodlela, isikhwama se-Aluminium foil, 25kg/Cardboard Drum, noma ngokwemfuneko yekhasimende
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Izinzuzo?Ikhwalithi ephezulu, intengo ethengekayo, izinsizakalo ezichwepheshile nokusekelwa kobuchwepheshe, ukulethwa okusheshayo.
IkhwalithiIsiqiniseko?Isistimu yokulawula ikhwalithi eqinile.Imishini yobuchwepheshe yokuhlaziya ifaka i-NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, NOMA, KF, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, njll.
Amasampula?Imikhiqizo eminingi inikeza amasampula wamahhala wokuhlolwa kwekhwalithi, izindleko zokuthumela kufanele zikhokhelwe amakhasimende.
Ukuhlolwa Kwemboni?Wamukelekile ekucwaningweni kwemboni.Sicela wenze i-aphoyintimenti kusengaphambili.
I-MOQ?Ayikho i-MOQ.I-oda elincane liyamukeleka.
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Amadokhumenti?Ngemuva kwenkonzo yokuthengisa: I-COA, i-MOA, i-ROS, i-MSDS, njll.
Custom Synthesis?Ingahlinzeka ngezinsizakalo zokwenziwa ngokwezifiso ukuze zilingane kangcono nezidingo zakho zocwaningo.
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I-L-Thyroxine (i-CAS: 51-48-9) noma i-Levothyroxine i-hormone yegilo yokwenziwa efana namakhemikhali ne-thyroxine (T4), ekhiqizwa ngokwemvelo ngamaseli e-follicular we-thyroid gland.Isetshenziselwa ukwelapha ukuntula kwe-hormone yegilo, futhi ngezinye izikhathi ukuvimbela ukuphindaphinda komdlavuza we-thyroid.Njengozakwabo ofihliwe ngokwemvelo, i-Levothyroxine iyinhlanganisela ye-chiral efomini le-L.Isidakamizwa esihlobene ne-dextrothyroxine (D-Thyroxine) sasisetshenziswa esikhathini esidlule njengokwelapha i-hypercholesterolemia (amazinga aphezulu e-cholesterol) kodwa sahoxiswa ngenxa yemiphumela emibi yenhliziyo.I-L-Thyroxine isetshenziselwa kakhulu ukwelapha i-hypothyroidism, i-goiter, i-lymphocytic thyroiditis engapheli, i-myxedema coma, ne-stupor.Ku-vivo, i-L-Thyroxine (0.9 kanye ne-2.7 μg) ivimbela ukuhlanganiswa nokukhululwa kwe-thyrotropin okubangelwa i-hormone ekhishwa i-thyrotropin kusuka ku-pituitary yangaphambili kumagundane.Amafomula aqukethe i-L-Thyroxine asetshenziswe ekwelapheni i-hypothyroidism.I-Levothyroxine therapy isetshenziswa esimweni sokuntuleka kwamahomoni egilo emzimbeni womuntu, njengoba kwenzeka ngaphansi kokuntuleka kwe-thyroid, i-pituitary kanye ne-hypothalamic hypothalamic (ngokulandelana kwe-primary, secondary and tertiary hypothyroidism).I-L-Thyroxine iphinde isetshenziswe ekwelapheni i-euthyroid goiter kanye ne-multinodular goiter, okuhlanganisa ama-nodule e-thyroid, i-subacute noma i-thyroiditis engapheli, noma esimweni sokushoda kwangemva kokuhlinzwa, noma ngemva kokwelashwa nge-radiometabolic ezigulini ezinomdlavuza we-thyroid.Imiphumela yalo muthi incike kakhulu kumthamo.Ngemithamo emincane, i-L-Thyroxine ibonisa isenzo se-anabolic.Ngemithamo ephakathi, ikhuthaza ukukhula nokuthuthukiswa kwezicubu, i-metabolism yamaprotheni, amafutha, nama-carbohydrates, yandisa umsebenzi wokusebenza kwesistimu yezinzwa ezimaphakathi nenhliziyo, kanye nezinso nesibindi.Ngemithamo emikhulu, inciphisa umsebenzi we-thyrotropic we-hypophysis futhi icindezela ukukhiqizwa kwendlala yegilo.
