I-Lenvatinib Mesylate Intermediate CAS 205448-65-3 Ubumsulwa >98.0% (HPLC) Isithombe Esifakiwe Sefekthri

I-Lenvatinib Mesylate Intermediate CAS 205448-65-3 Ubumsulwa >98.0% (HPLC) Factory

Incazelo emfushane:

Igama Lekhemikhali: Methyl 7-Methoxy-4-Oxo-1,4-Dihydroquinoline-6-Carboxylate

I-CAS: 205448-65-3

Ubumsulwa: >98.0% (HPLC)

Ukubukeka: Okumhlophe Okumhlophe ukuya Kokuphuzi

I-Intermediate ye-Lenvatinib Mesylate CAS 857890-39-2

E-Mail: alvin@ruifuchem.com

Thumela i-imeyili kithi

Imininingwane Yomkhiqizo

Imikhiqizo Ehlobene

Omaka bomkhiqizo

Incazelo:

I-Ruifu Chemical Supply Lenvatinib Mesylate Intermediates With High Purity
I-Lenvatinib Mesylate CAS 857890-39-2
4-Chloro-7-Methoxyquinoline-6-Carboxamide CAS 417721-36-9
I-Desquinolinyl Lenvatinib;1-(2-Chloro-4-Hydroxyphenyl)-3-Cyclopropylurea CAS 796848-79-8
I-Methyl 7-Methoxy-4-Oxo-1,4-Dihydroquinoline-6-Carboxylate CAS 205448-65-3
I-Methyl 4-Amino-2-Methoxybenzoate CAS 27492-84-8
5-(Methoxymethylene)-2,2-Dimethyl-1,3-Dioxane-4,6-Dione CAS 15568-85-1
I-4-Amino-3-Chlorophenol CAS 17609-80-2
I-4-Amino-3-Chlorophenol Hydrochloride CAS 52671-64-4
I-Methyl 4-Chloro-7-Methoxyquinoline-6-Carboxylate CAS 205448-66-4

Chemical Properties:

Igama Lekhemikhali	I-Methyl 7-Methoxy-4-Oxo-1,4-Dihydroquinoline-6-Carboxylate
Omqondofana	I-1,4-Dihydro-7-Methoxy-4-Oxo-6-Quinolinecarboxylic Acid Methyl Ester;I-7-Methoxy-4-Oxo-1,4-Dihydro-Quinoline-6-Carboxylic Acid Methyl Ester;I-Lenvatinib Intermediate 3
Inombolo ye-CAS	205448-65-3
Inombolo yeCAT	I-RF-PI1973
Isimo Sesitoko	Esitokweni, Amandla Okukhiqiza 50 MT/Unyaka
I-Molecular Formula	I-C12H11NO4
Isisindo samangqamuzana	233.22
Iphuzu elibilayo	421.0±45.0℃
Ukuminyana	1.267±0.060 g/cm3
Ibhrendi	I-Ruifu Chemical

Imininingwane:

Into	Imininingwane
Ukubukeka	I-Off-White to Yellowish Powder
Ukuhlanzeka / Indlela Yokuhlaziya	>98.0% (HPLC)
Ukulahlekelwa Ekumisweni	<1.00%
Izinsalela ekushiseni	<0.50%
Ukungcola Okuphelele	<2.00%
H-NMR	Ivumelana Nesakhiwo
Izinga Lokuhlola	I-Enterprise Standard
Ukusetshenziswa	Pharmaceutical Intermediates

Iphakheji nesitoreji:

Iphakheji: Ibhodlela, isikhwama se-Aluminium foil, 25kg/Cardboard Drum, noma ngokwemfuneko yekhasimende

Isimo Sesitoreji:Gcina ezitsheni ezivaliwe endaweni epholile neyomile;Vikela ekukhanyeni nakumswakama

Izinzuzo:

I-FAQ:

Isicelo:

I-Methyl 7-Methoxy-4-Oxo-1,4-Dihydroquinoline-6-Carboxylate (CAS: 205448-65-3) iphakathi kwe-Lenvatinib Mesylate (CAS: 857890-39-2).I-Lenvatinib, ethengiswa ngaphansi kwegama lomkhiqizo elithi Lenvima phakathi kokunye, umuthi wokulwa nomdlavuza wokwelapha izinhlobo ezithile zomdlavuza wegilo kanye neminye imidlavuza.Yakhiwe yi-Eisai Co. futhi isebenza njenge-multiple kinase inhibitor ngokumelene ne-VEGFR1, VEGFR2 kanye ne-VEGFR3 kinases.I-Lenvatinib ivunyelwe (kusukela ngo-2015) yokwelashwa komdlavuza we-thyroid ohlukile ophindeka endaweni noma we-metastatic, oqhubekayo, futhi ongaphenduli ekwelashweni nge-radioiodine (radioiodine).NgoMeyi 2016, i-US Food and Drug Administration (FDA) yagunyaza (ngokuhambisana ne-everolimus) ukuze zelashwe i-renal cell carcinoma ethuthukisiwe kulandela ukwelashwa okukodwa kwangaphambili kokulwa ne-angiogenic.Umuthi ugunyazwe nase-US nase-European Union nge-hepatocellular carcinoma engakwazi ukususwa ngokuhlinzwa ezigulini ezingazange zithole ukwelashwa komdlavuza ngomlomo noma ngomjovo.