I-Levosimendan Intermediate CAS 36725-28-7 Purity >99.5% (HPLC) Factory
Shanghai Ruifu Chemical Co., Ltd. is the leading manufacturer and supplier of 6-(4-Aminophenyl)-4,5-Dihydro-5-Methyl-3(2H)-Pyridazinone (CAS: 36725-28-7) with high quality, commercial production. We can provide COA, worldwide delivery, small and bulk quantities available. Please contact: alvin@ruifuchem.com
Igama Lekhemikhali | 6-(4-Aminophenyl)-4,5-Dihydro-5-Methyl-3(2H)-Pyridazinone |
Omqondofana | I-6-(p-Aminophenyl) -5-methyl-4,5-dihydro-3 (2H) -pyridazinone;1,4-Dihydro-4-Methyl-3-(4-Aminophenyl)pyridazine-6(5H)-eyodwa;Levosimendan Ukungcola 5 |
Inombolo ye-CAS | 36725-28-7 |
Inombolo yeCAT | I-RF-PI1976 |
Isimo Sesitoko | Esitokweni, Isikali Sokukhiqiza Sifinyelela Kumathani |
I-Molecular Formula | I-C11H13N3O |
Isisindo samangqamuzana | 203.25 |
I-Melting Point | 194.0 ukuze 198.0 ℃ |
Ukuminyana | 1.30±0.10 g/cm3 |
Ibhrendi | I-Ruifu Chemical |
Into | Imininingwane |
Ukubukeka | I-Off-White to Pale Brownish Color Powder |
I-Identification (HPLC) | I-HPLC RT yokuphakama okukhulu ihambisana naleyo yezinga lokusebenza langaphakathi |
Ukulahlekelwa Ekumisweni | <0.50% |
Izinsalela ekushiseni | <0.20% |
Izinto Ezihlobene | (HPLC) |
Ukungcola Okukodwa | <0.20% |
Ukungcola Okuphelele | <0.50% |
Ukuhlanzeka / Indlela Yokuhlaziya | >99.5% (HPLC) |
Izinsimbi Ezisindayo | <20ppm |
I-Proton NMR Spectrum | Ivumelana Nesakhiwo |
Izinga Lokuhlola | I-Enterprise Standard |
Ukusetshenziswa | I-Intermediate of Levosimendan (CAS: 141505-33-1) |
Iphakheji: Ibhodlela, isikhwama se-Aluminium foil, 25kg/Cardboard Drum, noma ngokwemfuneko yekhasimende
Isimo Sesitoreji:Gcina ezitsheni ezivaliwe endaweni epholile neyomile;Vikela ekukhanyeni nakumswakama
I-6-(4-Aminophenyl)-4,5-Dihydro-5-Methyl-3 (2H)-Pyridazinone (CAS: 36725-28-7) iphakathi kwe-Levosimendan (CAS: 141505-33-1).I-Levosimendan yethulwa eSweden njengomuthi we-iv wokwelapha ukwehluleka kwenhliziyo okunamandla noma izimpawu eziphikisayo zokuhluleka kwenhliziyo okungapheli ezimeni lapho ukwelashwa okuvamile (isb., i-diuretic noma i-ACE inhibitor) kunganele.Iphinde isebenze iziteshi ze-potassium ezilawulwa yi-ventricular kanye ne-arterial adenostne triphosphate-regulated potassium ezibangela i-vasodilatation emisipha ebushelelezi ye-vascular futhi ivikele i-myocardium ngokumelene ne-infarction.Umsebenzi wayo ophansi wokuvimbela i-phosphodiesterase III cishe awunasibopho semiphumela yayo emihle ye-inotropic, i-lusitropic kanye ne-dilating.Ngokungafani nezinye izidakamizwa ze-cardiotonic, i-levosimendan iyakwazi ukukhiqiza imiphumela emihle ye-inotropic ngaphandle kokwandisa ukuphumula kwe-myocardial noma ukwandisa izehlakalo ze-arrythmia eyingozi.Ngokomtholampilo kuboniswe ukuthi kunengozi ephansi yokufa ezigulini ezinokwehluleka kwenhliziyo uma kuqhathaniswa ne-placebo ne-dobutamine.Njengoba inamandla amakhulu, i-levosimendan okwamanje ingaphansi kokuhlolwa okwengeziwe komtholampilo njengokwelashwa okungapheli kokuhluleka kwenhliziyo ukuqunjelwa.