I-Luliconazole CAS 187164-19-8 Purity ≥99.0% HPLC Factory API High Quality
Nikeza i-Luliconazole kanye Nezixhumanisi Ezihlobene
I-Luliconazole CAS 187164-19-8
(1-Imidazolyl)i-acetonitrile CAS 98873-55-3
(S)-2,4-Dichloro-α-(Chloromethyl)benzyl Utshwala CAS 126534-31-4
| Igama Lekhemikhali | I-Luliconazole |
| Omqondofana | (2E)-2-[(4R)-4-(2,4-Dichlorophenyl)-1,3-dithiolan-2-ylidene]-2-(1H-imidazol-1-yl)acetonitrile;Isiqephu esingu-502 |
| Inombolo ye-CAS | 187164-19-8 |
| Inombolo yeCAT | I-RF-API110 |
| Isimo Sesitoko | Esitokweni, Isikali Sokukhiqiza Sifinyelela Kumathani |
| I-Molecular Formula | I-C14H9Cl2N3S2 |
| Isisindo samangqamuzana | 354.27 |
| I-Melting Point | 150.0 ukuze 154.0 ℃ |
| Ukuzungezisa Okuthile [a]20/D | -48.0° ukuya -53.0° (C=1, DMF) |
| Ukuncibilika | Ayincibiliki emanzini;Incibilika ku-acetone;Incibilika Kancane ku-Methanol |
| Ibhrendi | I-Ruifu Chemical |
| Into | Imininingwane |
| Ukubukeka | I-Off-White ukuya ku-Offur Crystalline Okhanyayo Ophuzi |
| Ukuhlonza IR | I-spectrum ye-infrared yesampula kufanele ihambisane naleyo yezinga lereferensi |
| Ukuhlonza HPLC | Isikhathi sokugcina sesiqongo esikhulu sesixazululo sesampula kufanele sihambisane naleso sesixazululo esijwayelekile njengoba sitholwe ekuhlolweni |
| Ukulahlekelwa Ekumisweni | ≤0.50% |
| Izinsalela ekushiseni | ≤0.20% |
| Izinsimbi Ezisindayo (Pb) | ≤20ppm |
| Izinto Ezihlobene | |
| Noma yikuphi Ukungcola Komuntu Ngamunye | ≤0.20% |
| Ukungcola Okuphelele | ≤0.50% |
| Izincibilikisi Ezisele | |
| I-Methanol | ≤3000ppm |
| I-acetonitrile | ≤410ppm |
| I-Dichloromethane | ≤600ppm |
| N-Hexane | ≤290ppm |
| I-Ethyl Acetate | ≤5000ppm |
| I-Tetrahydrofuran | ≤720ppm |
| I-Methyl tert-Butyl Ether | ≤5000ppm |
| I-N-Heptane | ≤5000ppm |
| I-Triethylamine | ≤320ppm |
| I-Dimethyl Sulfoxide | ≤5000ppm |
| Ukuhlanzeka / Indlela Yokuhlaziya | ≥99.0% (HPLC) (esomisiwe) |
| Izinga Lokuhlola | I-Enterprise Standard |
| Ukusetshenziswa | Pharmaceutical Intermediates |
Iphakheji: Ibhodlela, isikhwama se-Aluminium foil, 25kg/Cardboard Drum, noma ngokwezidingo zekhasimende.
Isimo Sesitoreji:Gcina ezitsheni ezivaliwe endaweni epholile neyomile;Vikela ekukhanyeni nakumswakama.
I-Luliconazole (i-CAS: 187164-19-8) iyi-antifungal imidazole elwa namagciwane ene-spectrum ebanzi nomsebenzi onamandla we-antifungal.I-Luliconazole uhlobo lwe-analogue ye-lanoconazole.Ingaphazamisa ukwakheka kodonga lwamaseli okukhunta kanye nokukhula kwesikhunta ngokunciphisa amazinga e-ergosterol ngokuvimbela umsebenzi we-lanosterol demethylase.Ngaphandle kokusetshenziselwa ukwelapha unyawo lomsubathi, i-jock itch kanye nezikelemu, iye yenzelwe nokwelapha i-onychomycosis (ukhunta lwezinzipho) futhi manje isingene esigabeni somtholampilo sesi-III.Lo mkhiqizo ekuqaleni wasungulwa yi-Japanese pesticide Corporation (NihonNohyaku Co., Ltd.).NgoNovemba 2013, i-FDA igunyaze ukhilimu we-luliconazole ongu-1% wokungena emakethe ukuze ulashwe unyawo lomsubathi osebenzisa idijithali, i-jock itch kanye nezikelemu ezinegama lokuhweba elithi Luzu futhi waqala ukungena emakethe eNyakatho Melika.Kusukela ngo-April 2005, i-luliconazole yayivunyelwe ukungena emakethe e-Japan ngaphansi kwegama lokuhweba elithi Lulicon.NgoJanuwari 2010 kanye noJuni 2012, yagunyazwa ukumakethwa eNdiya naseChina, ngokulandelana.
