I-Methyl 4-Chloro-7-Methoxyquinoline-6-Carboxylate CAS 205448-66-4 Purity >98.0% (HPLC) I-Lenvatinib Mesylate Intermediate Factory

Incazelo emfushane:

I-Methyl 4-Chloro-7-Methoxyquinoline-6-Carboxylate

I-CAS: 205448-66-4

Ubumsulwa: >98.0% (HPLC)

Ukubukeka: Okumhlophe Okumhlophe ukuya Kokuphuzi Okuqinile

I-Intermediate ye-Lenvatinib Mesylate CAS 857890-39-2

Ikhwalithi Ephezulu, Ukukhiqizwa Kwezohwebo

E-Mail: alvin@ruifuchem.com


Imininingwane Yomkhiqizo

Imikhiqizo Ehlobene

Omaka bomkhiqizo

Incazelo:

Chemical Properties:

Igama Lekhemikhali I-Methyl 4-Chloro-7-Methoxyquinoline-6-Carboxylate
Omqondofana I-Lenvatinib Ukungcola 47;4-Chloro-7-Methoxyquinoline-6-Carboxylic Acid Methyl Ester;4-Chloro-7-Methoxy-6-Quinolinecarboxylic Acid Methyl Ester;I-Lenvaint-D
Inombolo ye-CAS 205448-66-4
Inombolo yeCAT I-RF-PI1970
Isimo Sesitoko Esitokweni, Isikali Sokukhiqiza Sifinyelela Kumathani
I-Molecular Formula I-C12H10ClNO3
Isisindo samangqamuzana 251.67
Iphuzu elibilayo 377.4±37.0℃
Ukuminyana 1.320±0.06 g/cm3
Ibhrendi I-Ruifu Chemical

Imininingwane:

Into Imininingwane
Ukubukeka Impushana Eqinile Esukela Kumhlophe ukuya Ephuzi
1 H NMR Spectrum Ihambisana Nesakhiwo
Ukuhlanzeka / Indlela Yokuhlaziya >98.0% (HPLC)
Ukulahlekelwa Ekumisweni <1.00%
Ukungcola Okuphelele <2.00%
Izinga Lokuhlola I-Enterprise Standard
Ukusetshenziswa Okumaphakathi/Ukungcola kwe-Lenvatinib Mesylate (CAS: 857890-39-2)

Iphakheji nesitoreji:

Iphakheji: Ibhodlela, isikhwama se-Aluminium foil, 25kg/Cardboard Drum, noma ngokwemfuneko yekhasimende

Isimo Sesitoreji:Gcina ezitsheni ezivaliwe endaweni epholile neyomile;Vikela ekukhanyeni nakumswakama

Izinzuzo:

1

I-FAQ:

Isicelo:

I-Methyl 4-Chloro-7-Methoxyquinoline-6-Carboxylate (CAS: 205448-66-4) iphakathi kwe-Lenvatinib Mesylate (CAS: 857890-39-2).I-Lenvatinib iyisidakamizwa somdlavuza we-thyroid esakhiwe yi-Eisai Corporation yaseJapane (Ikhodi: E7080), eyingxenye ye-inhibitor ye-oral multi-receptor tyrosine kinase (RTK) futhi ingavimbela umsebenzi we-kinase we-vascular endothelial growth factor Receptors R1 (FLT1), I-VEG-FR2 (KDR), R3 (FLT4).I-Lenvatinib ingaphinde ivimbele ukubandakanyeka kwamanye ama-RTK ku-angiogenesis ye-pathological, ukukhula kwesimila, nokuqhubeka komdlavuza ngaphandle kwemisebenzi yawo evamile yamaselula kuhlanganise ne-fibroblast growth factor (FGF) receptors FGFR1, 2, 3, kanye ne-4;i-platelet-derived growth factor receptor (PDGFR [alpha]), i-KIT, ne-RET.[Izinkomba]: I-Lenvatinib ifanelekela ukwelapha iziguli ezinomdlavuza wegilo wokuphindaphinda kwendawo noma uhlobo lwe-metastasis, uhlobo lwe-progressivity kanye nohlobo oluhlukanisiwe lwe-radioactive iodine-refractory.

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