I-Molnupiravir N-1 CAS 2346620-55-9 COVID-19 Ikhwalithi ephezulu
I-Molnupiravir Yokuhlinzeka Ngezohwebo kanye Nezixhumanisi Ezihlobene Nekhwalithi Ephezulu
Uridine CAS 58-96-8
I-Cytidine CAS 65-46-3
I-Molnupiravir N-1 CAS 2346620-55-9
I-Molnupiravir (EIDD-2801) CAS 2349386-89-4
| Igama Lekhemikhali | I-Molnupiravir N-1 |
| Omqondofana | ((3aR,4R,6R,6aR)-6-(E)-4-(hydroxyimino)-2-oxo-3,4-dihydropyrimidin-1(2H)-yl)-2,2-dimethyltetrahydrofuro[3, 4-d][1,3]dioxol-4-yl)methyl isobutyrate;I-Molnupiravir Emaphakathi;I-Molnupiravir Dimethyl Dioxol Ukungcola;I-Molnupiravir Ukungcola 11 |
| Inombolo ye-CAS | 2346620-55-9 |
| Inombolo yeCAT | I-RF-PI310 |
| Isimo Sesitoko | Esitokweni, Isikali Sokukhiqiza Sifika Emakhulwini Amakhilogremu |
| I-Molecular Formula | I-C16H23N3O7 |
| Isisindo samangqamuzana | 369.37 |
| Ukuncibilika | I-Soluble ku-DMSO |
| Ukuminyana | 1.51±0.1 g/cm3 |
| Shipping Temperature | I-ambient |
| Ibhrendi | I-Ruifu Chemical |
| Into | Imininingwane |
| Ukubukeka | Impushana Emhlophe Kuya Kumhlophe |
| Ukulahlekelwa Ekumisweni | ≤1.0% |
| Izinsalela ekushiseni | ≤0.20% |
| Ukungcola Okukodwa | ≤0.50% |
| Ukungcola Okuphelele | ≤2.0% |
| Izinsimbi Ezisindayo | ≤20ppm |
| Ubumsulwa | ≥98.0% |
| Izinga Lokuhlola | I-Enterprise Standard |
| Ukusetshenziswa | Okumaphakathi kwe-Molnupiravir (CAS 2349386-89-4) COVID-19 |
Iphakheji: Ibhodlela, isikhwama se-Aluminium foil, isigubhu seCardboard, 25kg/Drum, noma ngokwezidingo zekhasimende.
Isimo Sesitoreji:Gcina ezitsheni ezivaliwe endaweni epholile neyomile;Vikela ekukhanyeni, umswakama kanye nezinambuzane.
I-Molnupiravir N-1 (CAS 2346620-55-9), imaphakathi ne-Molnupiravir (CAS 2349386-89-4) ekwelapheni i-COVID-19.I-Molnupiravir (EIDD-2801) iwuhlobo olutholakala ngomlomo lwe-bioavailable ye-ribonucleoside analog enamandla kakhulu evimbela ukuphindaphinda kwamagciwane amaningi e-RNA okuhlanganisa i-SARS-CoV-2, i-ejenti eyimbangela ye-COVID-19.I-EIDD-2801 (7 mg/kg; po; kabili ngosuku izinsuku ezingu-3.5) inciphisa ngokuphawulekayo umthamo wegciwane elichithiwe kanye nobude bemfiva.I-Molnupiravir (EIDD-2801) ifakwa kahle i-hydrolyzed ku-vivo ngemva kokumuncwa, okuholela ekutholweni kwe-NHC yamahhala kuphela ku-plasma.I-EIDD-2801 inciphisa ngokuqinile iziqu ezithathelwanayo ze-MERS-CoV, i-RNA yegciwane, kanye ne-pathogenesis ngaphansi kokubili kwezimo ze-prophylactic kanye nezimo zokuqala zokwelapha.I-Molnupiravir (EIDD-2801, MK-4482) iyisidakamizwa esitholakala ngomlomo se-ribonucleoside analog β-d-N4-hydroxycytidine (NHC; EIDD-1931) esinomphumela obanzi we-antiviral ngokumelene ne-SARS-CoV-2, MERS-CoV, I-SARS-CoV, kanye ne-ejenti eyimbangela ye-COVID-19.
