I-N-Acetyl-L-Cysteine CAS 616-91-1 (Ac-Cys-OH; NAC) Isivivinyo 98.5~101.0% Ikhwalithi Ephezulu Yefektri
I-Shanghai Ruifu Chemical Co., Ltd. ingumkhiqizi oholayo nomphakeli we-N-Acetyl-L-Cysteine (Ac-Cys-OH; NAC) (CAS: 616-91-1) enekhwalithi ephezulu.I-Ruifu Chemical ihlinzeka ngochungechunge lwama-amino acid nokuphuma kokunye.Ngenxa yekhwalithi yomkhiqizo wethu omuhle kakhulu, amanani aphansi, sazuza idumela elihle kanye nokwethenjwa kumakhasimende ethu asekhaya nawaphesheya.Singahlinzeka nge-COA, ukulethwa komhlaba wonke, amanani amancane kanye nenqwaba etholakalayo.Uma unentshisekelo ku-N-Acetyl-L-Cysteine,Please contact: alvin@ruifuchem.com
| Igama Lekhemikhali | I-N-Acetyl-L-Cysteine |
| Omqondofana | I-Ac-Cys-OH;i-acetylcysteine;I-NAC;I-LNAC;N-Acetylcysteine;I-N-Acetyl-3-Mercaptoalanine;I-Acetyl-Laevo-Cysteine |
| Isimo Sesitoko | Esitokweni, Amandla Okukhiqiza Amathani angama-50 ngenyanga |
| Inombolo ye-CAS | 616-91-1 |
| I-Molecular Formula | I-C5H9NO3S |
| Isisindo samangqamuzana | 163.19 |
| I-Melting Point | 106.0~108.0℃(lit.) |
| Kuyazwela | Kuyazwela emoyeni |
| Ukuncibilika kwamanzi | Incibilika Emanzini, Icishe Ikhanye |
| Ukuncibilika | Incibilika ku-Ethanol, Methanol, Utshwala.Ayincibiliki ku-Ether |
| Isikhathi Sokugcina. | Ivalwe Komile, Isitolo Emazingeni Okushisa Egumbi |
| I-COA ne-MSDS | Iyatholakala |
| Ukwahlukanisa | Ama-Amino Acid & Derivatives |
| Ibhrendi | I-Ruifu Chemical |
| Izitatimende Zobungozi | 36/37/38 - Ukucasula amehlo, uhlelo lokuphefumula kanye nesikhumba. |
| Izitatimende Zokuphepha | S22 - Ungaphefumuli uthuli.I-S24/25 - Gwema ukuthintana nesikhumba namehlo. |
| I-WGK Germany | 3 |
| I-RTECS | I-HA1660000 |
| F | 10-23 |
| I-TSCA | Yebo |
| Ikhodi ye-HS | 2922491990 |
| Izinto | Amazinga Wokuhlola | Imiphumela |
| Ukubukeka | Amakristalu amhlophe noma i-Crystalline Powder;I-Acid Taste Kakhulu | Kuyavumelana |
| Ukuhlonza | I-Infrared Absorption Spectrum | Kuyavumelana |
| Ukuzungezisa Okuthile [α]20/D | +21.3° ukuya +27.0° (C=5 ku-Phosphate Buffered Saline) | +23.5° |
| Isimo Sesixazululo (I-Transmittance) | Icacile futhi Ayinambala ≥98.0% | 99.0% |
| I-Chloride (Cl) | ≤0.040% | <0.040% |
| I-Sulfate (SO4) | ≤0.030% | <0.030% |
| I-Ammonium (NH4) | ≤0.020% | <0.020% |
| Insimbi (Fe) | ≤20ppm | <20ppm |
| Izinsimbi Ezisindayo (Pb) | ≤10ppm | <10ppm |
| I-Zinc (Zn) | ≤10ppm | <10ppm |
| I-Arsenic (As2O3) | ≤1.0ppm | <1.0ppm |
| Izinto Ezihlobene | (Indlela ye-HPLC) | |
| I-L-cystine | ≤0.50% | Kuyavumelana |
| I-L-cysteine | ≤0.50% | Kuyavumelana |
| N,N'-Diacetyl-L-Cystine | ≤0.50% | Kuyavumelana |
| N,S-Diacetyl-L-Cysteine | ≤0.50% | Kuyavumelana |
| Ukungcola Komunye nomunye | ≤0.50% | Kuyavumelana |
| Ukungcola Okuphelele | ≤0.50% | Kuyavumelana |
| Ukulahlekelwa Ekumisweni | ≤0.50% | 0.20% |
| Izinsalela ekushiseni (Sulfated) | ≤0.20% | 0.05% |
| Isivivinyo | 98.5 kuya ku-101.0% (Ngesisekelo Esomisiwe) | 99.90% |
| Inani le-pH | 2.0 kuye ku-2.8 (1.0g ku-100ml we-H2O) | 2.5 |
| Ubuthi be-Biochemical | Amaphasi | Amaphasi |
| Izinto eziphilayo eziguquguqukayo | Dlula | Dlula |
| Ukutholwa kwe-Endonuclease | ≤0.1 EU/g | <0.1 EU/g |
| Isiphetho | Lo Mkhiqizo Ngokuhlola Uvumelana Nezinga le-AJI97 | |
| Ukusetshenziswa Okuyinhloko | Ama-amino Acids;Izithasiselo Zokudla;Pharmaceutical Intermediates | |
Iphakheji: Ibhodlela eliFluorinated, isikhwama se-Aluminium foil, 25kg/Cardboard Drum, noma ngokwezidingo zekhasimende.
Isimo Sesitoreji:Gcina ezitsheni ezivaliwe endaweni epholile, eyomile futhi engenamoya kude nezinto ezingahambelani.Vikela ekukhanyeni nakumswakama.
I-N-Acetyl-L-Cysteine (Ac-Cys-OH; NAC) (CAS: 616-91-1) AJI97 Indlela Yokuhlola
I-N-Acetyl-L-Cysteine, uma yomisiwe, iqukethe amaphesenti angekho ngaphansi kuka-98.5 futhi hhayi ngaphezu kwamaphesenti angu-101.0 we-N-Acetyl-L-Cysteine (C5H9NO3S).
Incazelo: Amakristalu amhlophe noma i-crystalline powder, ukunambitheka kwe-asidi enamandla.
Incibilika ngokukhululeka emanzini, inyibilika ku-ethanol, ayincibiliki ku-ether.
Ukunyibilika (H2O, g/100g): 17 (20℃), 80 (40℃), 260 (60℃)
Ukuhlonza: Qhathanisa i-spectrum yokumuncwa kwe-infrared yesampula naleyo yezinga lendlela ye-potassium bromide disc.
Ukuzungezisa Okuthile [α]20/D: Isampula eyomisiwe, C=8, isisombululo sebhafa ye-phosphate
Isimo Sesixazululo (Ukudluliswa): 0.5g ku-10ml ye-H2O, i-spectrophotometer, 430nm, 10mm ubukhulu beseli.
Izinsimbi Ezisindayo (Pb): 2.0g, (1), ref: 2.0ml ye-Pb Std.(0.01mg/ml)
I-Zinc (Zn): Indlela yokumunca i-athomu
Izinto Ezihlobene: Indlela ye-HPLC
Ukulahlekelwa Ekumisweni: Ku-vacuum, ku-70 ℃ amahora angu-4
Izinsalela Ekushiseni (I-Sulfated): Ukuhlolwa kwe-AJI 13
I-Assay: Isampula eyomisiwe, 200mg, 0.05mol/L I2 1ml=16.320mg C5H9NO3S
pH: 1.0g ku-100ml ye-H2O
Umkhawulo wokulondoloza onconyiwe nesimo: Iziqukathi ezigciniwe eziqinile ezingeni lokushisa elilawulwayo legumbi (unyaka ongu-1).
I-N-Acetyl-L-Cysteine (Ac-Cys-OH; NAC) (CAS: 616-91-1) Indlela Yokuhlola ye-USP35
INCAZELO
I-Acetylcysteine iqukethe i-NLT 98.0% kanye ne-NMT 102.0% ye-L-threonine (C5H9NO3S), ebalwa ngokomisiwe.
UKUKHOMBA
A. UKUMUMVA OKUTHI INFRARED <197K>
ISIVIVINYO
INQUBO
Isigaba sikamakhalekhukhwini: 6.8 g/L we-monobasic potassium phosphate.Lungisa nge-phosphoric acid ibe yi-pH engu-3.0.
Isixazululo se-sodium metabisulfite: 0.5 mg/mL ye-sodium metabisulfite emanzini, esanda kulungiswa
Isixazululo sangaphakathi esijwayelekile: 5 mg/mL ye-USP L-Phenylalanine RS kusixazululo se-Sodium metabisulfite
Isixazululo esijwayelekile sesitoko: 10 mg/mL we-USP Acetylcysteine RS kusixazululo se-Sodium metabisulfite
Isixazululo esijwayelekile: 0.5 mg/mL we-USP Acetylcysteine RS kanye no-0.25 mg/mL we-USP L-Phenylalanine RS kusixazululo se-Sodium metabisulfite kusuka kusixazululo sesitoko Esijwayelekile kanye nesixazululo esijwayelekile sangaphakathi
Isixazululo sesitoko esiyisampula: 10 mg/mL ye-Acetylcysteine kusisombululo se-Sodium metabisulfite
Isixazululo esiyisampula: 0.5 mg/mL ye-Acetylcysteine kanye no-0.25mg/mL ye-USP L-Phenylalanine RS kusixazululo se-Sodium metabisulfite esiphuma kusixazululo sesitoko esiyisampula kanye nesixazululo esijwayelekile sangaphakathi
Isistimu yeChromatographic
(Bona i-Chromatography <621>, Ukufaneleka Kwesistimu.)
Imodi: LC
Umtshina: UV 214 nm
Ikholomu: 3.9-mm × 30-cm;ukupakisha L1
Izinga lokugeleza: 1.5 mL/min
Usayizi womjovo: 5 µL
Ukufaneleka kwesistimu
[QAPHELA-Izikhathi zokugcinwa okuhlobene kwe-acetylcysteine ne-L-phenylalanine cishe zingu-0.5 kanye no-1.0, ngokulandelana.]
Izidingo zokufaneleka
Isixazululo: I-NLT 6 phakathi kwe-acetylcysteine ne-L-phenylalanine
Ukuchezuka okujwayelekile okuhlobene: NMT 2.0%
Ukuhlaziya
Amasampula: Isixazululo esijwayelekile kanye nesixazululo esiyisampula
Bala iphesenti le-acetylcysteine (C5H9NO3S) engxenyeni ye-Acetylcysteine ethathiwe:
Umphumela = (RU/RS) × (CS/CU) × 100
I-RU = isilinganiso sokuphendula esiphezulu se-acetylcysteine ku-L-phenylalanine kusukela kusixazululo seSampuli
I-RS = isilinganiso esiphezulu sempendulo ye-acetylcysteine kuya ku-L-phenylalanine kusukela kusixazululo Esijwayelekile
CS = ukugxila kwe-USP Acetylcysteine RS kusixazululo Esijwayelekile (mg/mL)
I-CU = ukuhlushwa kwe-acetylcysteine esixazululweni sesampula (mg/mL)
Indlela yokwamukela: 98.0% -102.0% ngokomisiwe
UKUNGCOLA
ISALELA EKUSHISENI <281>: NMT 0.5%
IZINSIMBI EZINZIMA, Indlela II <231>
[ISIXWAYISO-Qinisekisa umzimba ngoba ukuqhuma kungase kwenzeke.]
Ukuhlaziya: Ngendlela eyehlayo, manzisa isampula ngo-2 mL we-nitric acid, futhi uqhubeke njengoba kuqondiswe ekulungiseleleni Ukuhlolwa.
Indlela yokwamukela: NMT 10 ppm
IZIVIVINYO EZITHILE
UKUZUNGUZA KOMBONISO, Ukuzungezisa Okuqondile <781S>
I-Buffer: Xuba u-29.5 mL we-1 N sodium hydroxide, 50 mL we-1 M monobasic potassium phosphate, namanzi anele ukwenza u-100 mL.Lungisa i-pH engu-7.0 ± 0.1 ngokungeza esinye sanoma yisiphi isisombululo, njengoba kudingekile.
Isixazululo esiyisampula: Ku-25-mL ye-volumetric flask, hlanganisa u-1.25 g ne-1 mL yesisombululo se-edetate disodium (1 ku-100), engeza u-7.5mL wesisombululo se-sodium hydroxide (1 ku-25), bese uxuba ukuze uncibilike.Nciphisa nge-Buffer kuvolumu.
Imibandela yokwamukela: +21° ukuya +27°
i-pH <791>: 2.0-2.8 kusixazululo (1 ku-100)
UKULAHLEKELWA EKOMISENI <731>: Yomisa isampula ngokucindezela okungaba ngu-50 mm we-mer cury ku-70° amahora angu-4: ilahlekelwa yi-NMT 1.0% yesisindo sayo.
IZIDINGO EZENGEZIWE
UKUPAKASHWA KANYE NESIGCINI: Londoloza ezitsheni eziqinile, futhi ugcine endaweni yokushisa elawulwayo yegumbi.
I-USP REFERENCE AMAZINGA <11>
USP Acetylcysteine RS
USP L-Phenylalanine RS
Indlela Yokuthenga?Sicela uxhumaneDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
Iminyaka engu-15 Yokuhlangenwe nakho?Sinesipiliyoni seminyaka engaphezu kwe-15 ekwakhiweni nasekuthumeleni kwamanye amazwe uhla olubanzi lwezinga eliphezulu lokuxhumanisa imithi noma amakhemikhali amahle.
Izimakethe Eziyinhloko?Thengisa emakethe yasekhaya, eNyakatho Melika, eYurophu, eNdiya, eKorea, eJapane, e-Australia, njll.
Izinzuzo?Ikhwalithi ephezulu, intengo ethengekayo, izinsizakalo ezichwepheshile nokusekelwa kobuchwepheshe, ukulethwa okusheshayo.
IkhwalithiIsiqiniseko?Isistimu yokulawula ikhwalithi eqinile.Imishini yobuchwepheshe yokuhlaziya ifaka i-NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, NOMA, KF, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, njll.
Amasampula?Imikhiqizo eminingi inikeza amasampula wamahhala wokuhlolwa kwekhwalithi, izindleko zokuthumela kufanele zikhokhelwe amakhasimende.
Ukuhlolwa Kwemboni?Wamukelekile ekucwaningweni kwemboni.Sicela wenze i-aphoyintimenti kusengaphambili.
I-MOQ?Ayikho i-MOQ.I-oda elincane liyamukeleka.
Isikhathi sokuthumela? Uma kungaphakathi kwesitoko, ukulethwa kwezinsuku ezintathu kuqinisekisiwe.
Ezokuthutha?By Express (FedEx, DHL), by Air, by Sea.
Amadokhumenti?Ngemuva kwenkonzo yokuthengisa: I-COA, i-MOA, i-ROS, i-MSDS, njll.
Custom Synthesis?Ingahlinzeka ngezinsizakalo zokwenziwa ngokwezifiso ukuze zilingane kangcono nezidingo zakho zocwaningo.
Imigomo Yokukhokha?I-invoyisi ye-Proforma izothunyelwa kuqala ngemva kokuqinisekiswa kwe-oda, kufakwe nemininingwane yethu yasebhange.Inkokhelo nge-T/T (Telex Transfer), PayPal, Western Union, njll.
Umsebenzi nokusetshenziswa kwe-N-Acetyl-L-Cysteine (Ac-Cys-OH; NAC) (CAS: 616-91-1) powder
1. I-N-Acetyl-L-Cysteine, eyaziwa nangokuthi i-N-Acetylcysteine noma i-Acetylcysteine (NAC), iyisidakamizwa sokwenza imithi kanye nesengezo sokudla okunempilo esisetshenziswa ngokuyinhloko njenge-ejenti ye-mucolytic nasekulawuleni ukweqisa kwe-paracetamol (acetaminophen).Okunye ukusetshenziswa kufaka ukugcwala kwe-sulfate ezimeni, njenge-autism, lapho i-cysteine kanye nama-amino acid esibabule ahlobene angase aphele.
2. I-N-Acetyl-L-Cysteine iphuma ku-cysteine lapho iqembu le-acetyl lixhunywe ku-athomu ye-nitrogen.Le nhlanganisela ithengiswa njengesengezo sokudla esivame ukubiza imiphumela ye-antioxidant nesibindi.Isetshenziswa njengomuthi wokukhwehlela ngoba iphula izibopho ze-disulfide kumafinyila futhi iwuketshezi, okwenza kube lula ukukhwehlela.Futhi yilesi senzo sokuphula izibopho ze-disulfide esenza kube usizo ekunciphiseni amafinyila aminyene ngokungavamile ezigulini ezine-cystic kanye ne-pulmonary fibrosis.
3. I-Acetylcysteine iyi-agent ye-mucolytic enomphumela onamandla we-mucolytic.Iqembu le-sulfhydryl eliqukethwe ku-molecule linganqamula isibopho se-disulfide ochungechungeni lwe-glycoprotein polypeptide esikhwehlela, ngaleyo ndlela linciphise ukubukeka kwesikhwehlela, futhi lenze isikhwehlela sibe uketshezi futhi kube lula ukukhwehlela.Lo mkhiqizo ungaphinda uphule imicu ye-DNA ku-sputum e-purulent, ngakho-ke awukwazi nje ukuqeda isikhwehlela esimhlophe esinamathelayo, kodwa futhi nesikhwehlela esinama-purulent.Ezigulini ama-expectorants azo ajwayelekile angasebenzi, lo mkhiqizo usengasebenza.
4. Isetshenziswa njengomuthi wokuncibilikisa i-phlegm.Isetshenziswa ocwaningweni lwe-biochemical kanye nemithi njengekhambi le-phlegm kanye nobuthi be-acetaminophen.I-biochemical reagent, umuthi, lo mkhiqizo usetshenziswa njenge-expectorant, wathi i-phlegm kulula ukuyihlanza.
5. Imiphumela engemihle evamile ihlanganisa isicanucanu nokuhlanza lapho uthathwa ngomlomo. Isikhumba singase sibe bomvu futhi silume nganoma iyiphi indlela.Kungase kwenzeke futhi uhlobo olungavikelekile lwe-anaphylaxis.Kubonakala kuphephile ekukhulelweni.Nge-overdose ye-paracetamol, isebenza ngokukhuphula izinga le-glutathione, i-antioxidant enganciphisa imikhiqizo eyingozi ye-paracetamol.Uma ihogelwa, isebenza njenge-mucolytic ngokunciphisa ukushuba kwe-mucus.
6. I-Acetylcysteine yaqala ukugunyazwa ngo-1960 futhi yaqala ukusetshenziswa kwezokwelapha ngo-1968. Isohlwini lwe-World Health Organization Lwemithi Ebalulekile, olubala imithi ephephile nesebenza ngempumelelo kakhulu edingekayo ohlelweni lwezempilo.Itholakala njengemithi ejwayelekile futhi ayibizi.
7. I-N-Acetyl-L-Cysteine iwuhlobo lwe-acetylated lwe-L-cysteine olumuncwa kahle futhi lusetshenziswe.Futhi iyi-antioxidant ewusizo ngokumelene namagciwane.I-N-Acetyl-l-Cysteine isetshenziswe njengesivikelo sesibindi kanye nokuhlakaza amafinyila wamaphaphu kanye ne-bronchial.
8. I-N-Acetyl-L-Cysteine ingakhuphula amazinga e-glutathione kumaseli.
9. I-N-Acetyl-L-Cysteine iyi-amino acid ebalulekile ngokwemibandela, eyodwa kuphela kwama-amino acid amathathu anesulfure, amanye kuyi-taurine (engakhiqizwa ku-L-cysteine) kanye ne-L-methionine lapho i-L-cysteine ingakwazi khona. kukhiqizwa emzimbeni ngenqubo enezinyathelo eziningi.
10. I-N-Acetyl-L-Cysteine ingasebenza njenge-antioxidant, ingase ivimbele izifo zesibindi, futhi ingasiza ekuqiniseni ububanzi bomuntu ngamunye bezinwele ezikhona uma kuthathwa njalo.
11. Isicelo emikhakheni yezokwelapha Njenge-ejenti yohlelo lokuphefumula, ingasetshenziswa njengomuthi wokuncibilikisa izigubhu zephlegm.iyakwazi ukwelapha i-bronchitis.ngaphezu kwalokho, i-N-Acetyl-L-Cysteine ingasetshenziswa njenge-antidote lapho ubuthi be-acetaminophen.
12. Ukusetshenziswa emikhakheni yezimonyo i-N-Acetyl-L-Cysteine ibe nomthelela omkhulu ekuhlanzeni ama-radicals angenayo i-oxygen namanye ama-oxide futhi ibambezele inqubo yokuguga, futhi ingaphazamisa ukukhiqizwa kwe-melanin, futhi iyasiza ekuqedeni ama-freckle esikhumbeni.
13. Ukufakwa ekudleni kwezilwane i-N-Acetyl-L-Cysteine ingasetshenziswa njengesengezo sokudla.
14. Izimonyo ezisetshenziselwa ikakhulukazi amanzi obuhle, uketshezi lwe-perm, ukhilimu wokunakekela isikhumba ongamelana nelanga.Inomsebenzi wokuvimbela ukuguga kwezinto eziphilayo.I-N-Acetyl-l-Cysteine ingavimbela ngempumelelo futhi yelaphe ukulimala kwemisebe.I-N-acetyl Cysteine ingakwazi ukususa i-melanin yesikhumba ngokwayo, iguqule isimo sesikhumba ngokwaso, isikhumba sibe mhlophe ngokwemvelo.Iwuhlobo lwezimonyo ezilungile zemvelo ezimhlophe.
15. Isengezo sokudla.Isetshenziselwa isinkwa, ukukhuthaza ukwakheka kwe-gluten nokukhuthaza ukuvutshelwa, isikhunta, ukuvimbela ukuguga.Isetshenziswa kumajusi emvelo ukuvimbela uvithamini C ukuthi angangeni oxidizing kanye nokuvimbela amajusi ukuthi angashintshi abe nsundu.
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