I-N-Acetyl-L-Tyrosine CAS 537-55-3 (Ac-Tyr-OH; NALT) Isivivinyo 99.0~101.0 Ifektri
I-Shanghai Ruifu Chemical Co., Ltd. ingumkhiqizi ohamba phambili kanye nomphakeli we-N-Acetyl-L-Tyrosine (Ac-Tyr-OH; NALT) (CAS: 537-55-3) enekhwalithi ephezulu.I-Ruifu Chemical ihlinzeka ngochungechunge lwama-amino acid nokuphuma kokunye.Umkhiqizo wekhwalithi ephezulu, intengo enengqondo, insizakalo enhle kakhulu futhi esheshayo yangemva kokuthengisa kuyizibopho ze-Ruifu Chemical kumakhasimende.Singahlinzeka nge-COA, ukulethwa komhlaba wonke, amanani amancane kanye nenqwaba etholakalayo.Uma unentshisekelo ku-N-Acetyl-L-Tyrosine,Please contact: alvin@ruifuchem.com
| Igama Lekhemikhali | I-N-Acetyl-L-Tyrosine |
| Omqondofana | I-Ac-Tyr-OH;I-Ac-L-Tyr-OH;N-Ac-L-Tyr;I-NALT;I-Ac-Tyrosine;i-acetyltyrosine;I-N-Acetyltyrosine;I-Acetyl-Laevo-Tyrosine;I-LN-Acetyltyrosine;(2S)-2-(Acetylamino)-3-(4-Hydroxyphenyl)Propanoate;(S)-2-Acetamido-3-(4-Hydroxyphenyl)propanoic Acid;I-N-Acetyl-(S)-2-Amino-3-(4-Hydroxyphenyl)propionic Acid;(2S)-2-(Acetylamino)-3-(4-Hydroxyphenyl)propanoic Acid |
| Isimo Sesitoko | Esitokweni, Amandla Okukhiqiza Amathani angama-30 ngonyaka |
| Inombolo ye-CAS | 537-55-3 |
| I-Molecular Formula | I-C11H13NO4 |
| Isisindo samangqamuzana | 223.23 g/mol |
| I-Melting Point | 150.0 ukuze 154.0 ℃ |
| Ukuminyana | 1.304 |
| Ukuncibilika kwamanzi | Incibilika Emanzini, Icishe Ikhanye |
| Isikhathi Sokugcina. | Ivalwe Komile, Isitolo Emazingeni Okushisa Egumbi |
| I-COA ne-MSDS | Iyatholakala |
| Ukwahlukanisa | Ama-Amino Acid & Derivatives |
| Ibhrendi | I-Ruifu Chemical |
| Amakhodi Wengozi | Xi - Iyacasula | F | 10 |
| Izitatimende Zobungozi | 41-36/37/38 | I-TSCA | Yebo |
| Izitatimende Zokuphepha | 26-39-36 | Ikhodi ye-HS | 2922491990 |
| I-WGK Germany | 3 |
| Izinto | Amazinga Wokuhlola | Imiphumela |
| Ukubukeka | Amakristalu Amhlophe noma I-Crystalline Powder | Kuyavumelana |
| Ukuhlonza | I-Infrared Absorption Spectrum | Kuyavumelana |
| Ukuzungezisa Okuthile [α]20/D | +46.5° ukuya +49.0°(C=2 ku-H2O) | +47.2° |
| Isimo Sesixazululo (I-Transmittance) | ≥96.0% | 98.3% |
| I-Chloride (Cl) | ≤0.020% | <0.020% |
| I-Sulfate (SO4) | ≤0.020% | <0.020% |
| I-Ammonium (NH4) | ≤0.020% | <0.020% |
| Insimbi (Fe) | ≤30ppm | <30ppm |
| Izinsimbi Ezisindayo (Pb) | ≤10ppm | <10ppm |
| I-Arsenic (As2O3) | ≤2.0ppm | <2.0ppm |
| I-Tyrosine | ≤1.00% | Kuyavumelana |
| Ukulahlekelwa Ekumisweni | ≤0.50% | 0.25% |
| Izinsalela ekushiseni (Sulfated) | ≤0.10% | 0.07% |
| Isivivinyo | 99.0 kuya ku-101.0% | 99.5% |
| Inani le-pH | 2.0 kuye ku-3.0 | 2.3 |
| Isiphetho | Ihlangabezana Nezinga le-AJI97, USP35 | |
| Ukusetshenziswa Okuyinhloko | Izithasiselo Zokudla;Izithasiselo Zokudla;Pharmaceutical Intermediates | |
I-N-Acetyl-L-Tyrosine (Ac-Tyr-OH; NALT) (CAS: 537-55-3) AJI97 Indlela Yokuhlola
I-N-Acetyl-L-Tyrosine, uma yomisiwe, iqukethe amaphesenti angekho ngaphansi kuka-99.0 futhi hhayi ngaphezu kwamaphesenti angu-101.0 we-N-Acetyl-L-Tyrosine (C11H13NO4).
Incazelo: Amakristalu amhlophe noma i-crystalline powder, ukunambitheka kwe-asidi enamandla
Incibilika ngokukhululekile emanzini.
Ukunyibilika (H2O, g/100g): 17.5 (20℃), 72.4 (40℃), 158 (60℃)
Ukuhlonza: Qhathanisa i-spectrum yokumuncwa kwe-infrared yesampula naleyo yezinga lendlela ye-potassium bromide disc.
Ukuzungezisa Okuthile [α]20/D: Isampula elomisiwe, C=4, H2O
Isimo Sesixazululo (Ukudluliswa): 0.5g ku-10ml ye-H2O, i-spectrophotometer, 430nm, 10mm ubukhulu beseli.
I-Chloride (Cl): 0.7g, A-1, ref: 0.40ml ka-0.01mol/L HCl
I-Ammonium (NH4): B-1
I-Sulfate (SO4): 1.2g, (1), ref: 0.50ml ka-0.005mol/L H2SO4
I-ayoni (Fe): 0.5g, ref: 1.5ml ye-Iron Std.(0.01mg/ml)
Izinsimbi Ezisindayo (Pb): 2.0g, (3), ref: 2.0ml ye-Pb Std.(0.01mg/ml)
I-Arsenic (As2O3): 1.0g, (1), ref: 2.0ml ye-As2O3 Std.
Ukulahlekelwa Ekumisweni: ku-105 ℃ amahora angu-3
Izinsalela Ekushiseni (I-Sulfated): Ukuhlolwa kwe-AJI 13
I-Assay: Isampula eyomisiwe, 300mg, (1), 40ml H2O, (2), 0.1mol/L NaOH, 1ml=22.323mg C11H13NO4
I-Tyrosine: I-chromatography ewuketshezi.Isimo sokusebenza: Umtshina: I-photometer yokumuncwa kwe-UV (214nm);Ikholomu: ODS, 4.6mm x 150mm;Izinga Lokushisa Lekholomu: Izinga lokushisa legumbi.Izinga lokugeleza: 1ml / min;Isigaba seselula: 0.04mol/L isisombululo se-monopotassium phosphate (pH 4.35): I-Methanol (193:3)
pH: 1.25g ku-50ml we-H2O
Umkhawulo wokulondoloza onconyiwe nesimo: Iziqukathi ezigciniwe eziqinile ezingeni lokushisa elilawulwayo legumbi (iminyaka emi-2).
I-N-Acetyl-L-Tyrosine (Ac-Tyr-OH; NALT) (CAS: 537-55-3) Indlela Yokuhlola ye-USP35
INCAZELO
I-N-Acetyltyrosine iqukethe i-NLT 98.5% kanye ne-NMT 101.0% ye-C11H13NO4, njenge-N-Acetyl-L-Tyrosine, ibalwe ngokomisiwe.
UKUKHOMBA
A. UKUMUMVA OKUTHI INFRARED <197K>
B. UKUZUNGUZA KOMBONISO, Ukuzungezisa Okuqondile <781S>
Isixazululo sesampula: 10 mg/mL
Imibandela yokwamukela: I-NLT +46.0° ne-NMT +49.0°, inqunywa kokuthi 20°
C. Inani le-RF lendawo eyinhloko yesisombululo Sesampuli ekuhlolweni Kokungcola Kwezinto Eziphilayo lihambisana nalelo Lesixazululo Esijwayelekile 1.
ISIVIVINYO
INQUBO
Isixazululo sesampula: Chaza cishe u-180 mg we-N-Acetyltyrosine, ukalwe, ku-50 mL wamanzi angenayo i-carbon dioxide.
Isistimu ye-Titrimetric
(Bheka i-Titrimetry <541>)
Imodi: I-titration eqondile
I-Titrant: 0.1 N i-sodium hydroxide VS
Ukutholwa kwendawo yokugcina: I-Potentiometric
Ukulingana: I-mL ngayinye ye-0.1 N sodium hydroxide VS ilingana no-22.32 mg we-C11H13NO4.
UKUNGCOLA
Ukungcola Okungaphili
UKUSHISA OKUSELELE <281>: NMT 0.1%
I-CHLORIDE NE-SULFATE, I-Chloride <221> NMT 200 ppm.Ingxenye engu-0.7-g ibonisa ukuthi ayisekho i-chloride ehambisana no-0.40 mL ka-0.01 N hydrochloric acid.
I-CHLORIDE NE-SULFATE, i-Sulfate <221> NMT 200 ppm.Ingxenye engu-1.2-g ayibonisi i-sulfate engaphezu kwe-0.25 mL ka-0.020 N sulfuric acid.
I-IRON <241>: NMT 20ppm
IZINSIMBI EZISINDAYO, Indlela I <231>: NMT 10ppm
Ukungcola Okuphilayo
INQUBO
I-Adsorbent: 0.25-mm ungqimba lwengxube yejeli yesilica yechromatographic
Isixazululo sesitoko esijwayelekile 1: 8 mg/mL se-USP N-Acetyl-L-tyrosine RS kwingxube yamanzi, i-glacial acetic acid, notshwala (3:3:94)
Isixazululo 1 esijwayelekile: Nciphisa isixazululo sesitoko Esijwayelekile 1 ngotshwala ukuze uthole isixazululo esinokugxila okwaziwayo okungaba ngu-0.4 mg/mL
Isixazululo esijwayelekile esingu-2: 0.8 mg/mL ye-USP L-Tyrosine RS encibilikisiwe engxubeni ye-glacial acetic acid namanzi (1:1), futhi ehlanjululwe ngotshwala
Isixazululo esiyisampula: Dlulisa u-0.8 g we-N-Acetyltyrosine ku-10-mL ye-volumetric flask, ncibilikisa ngo-6 mL wengxube ye-glacial acetic acid namanzi (1:1), bese uxubisa ngotshwala ngevolumu.
Ivolumu yohlelo lokusebenza: 5 µL
Ukuthuthukisa uhlelo lokuncibilikisa: Ingxube ye-ammonia ne-2-propanol (3:7)
I-reagent yokufutha: Chaza u-0.2 g we-ninhydrin ku-100 mL wengxube ye-butanol no-2 N acetic acid (95:5).
Ukufaneleka kwesistimu
Izidingo zokufaneleka: Ichromatogram yesisombululo sokufaneleka Kwesistimu ibonisa izindawo ezimbili ezihlukene ngokusobala.
Ukuhlaziya: Qhubeka njengoba kuqondiswe ku-Chromatography <621> Thin-Layer Chromatography.Ngemva kokumisa ipuleti emoyeni, phinda inqubo yokuthuthukisa.Ngemva kokumisa emoyeni okwesibili, fafaza nge-Spray reagent, bese ushisa phakathi kuka-100° no-105° cishe imizuzu eyi-15.
Imibandela yokwamukela: Noma iyiphi indawo yesibili yesisombululo Sesampuli ayinkulu noma iqine kakhulu kunendawo eyinhloko Yesixazululo Esijwayelekile1, ngaphandle kwendawo ehambisana ne-tyrosine, engenkulu noma iqine kakhulu kunendawo eyinhloko evela kusixazululo Esijwayelekile 2.
Ukungcola komuntu ngamunye: NMT 0.5%
Umkhawulo we-tyrosine: NMT 1.0%
IZIVIVINYO EZITHILE
I-LASSON DRYING <731>: Yomisa isampula ku-105℃ amahora angu-3: ilahlekelwa yi-NMT 0.1% yesisindo sayo.
IZIDINGO EZENGEZIWE
UKUPAKASHWA KANYE NESIGCINI: Londoloza ezitsheni ezivalwe kahle, futhi ugcine endaweni elawulwayo ekamelweni lokushisa.
I-USP REFERENCE AMAZINGA <11>
I-USP N-Acetyl-L-tyrosine RS
I-USP L-Tyrosine RS
Iphakheji: Ibhodlela eliFluorinated, isikhwama se-Aluminium foil, 25kg/Cardboard Drum, noma ngokwezidingo zekhasimende.
Isimo Sesitoreji:Gcina ezitsheni ezivaliwe endaweni epholile, eyomile futhi engenamoya kude nezinto ezingahambelani.Vikela ekukhanyeni nakumswakama.Gwema ama-oxidizing agents aqinile.
Indlela Yokuthenga?Sicela uxhumaneDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
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Izimakethe Eziyinhloko?Thengisa emakethe yasekhaya, eNyakatho Melika, eYurophu, eNdiya, eKorea, eJapane, e-Australia, njll.
Izinzuzo?Ikhwalithi ephezulu, intengo ethengekayo, izinsizakalo ezichwepheshile nokusekelwa kobuchwepheshe, ukulethwa okusheshayo.
IkhwalithiIsiqiniseko?Isistimu yokulawula ikhwalithi eqinile.Imishini yobuchwepheshe yokuhlaziya ifaka i-NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, NOMA, KF, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, njll.
Amasampula?Imikhiqizo eminingi inikeza amasampula wamahhala wokuhlolwa kwekhwalithi, izindleko zokuthumela kufanele zikhokhelwe amakhasimende.
Ukuhlolwa Kwemboni?Wamukelekile ekucwaningweni kwemboni.Sicela wenze i-aphoyintimenti kusengaphambili.
I-MOQ?Ayikho i-MOQ.I-oda elincane liyamukeleka.
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Amadokhumenti?Ngemuva kwenkonzo yokuthengisa: I-COA, i-MOA, i-ROS, i-MSDS, njll.
Custom Synthesis?Ingahlinzeka ngezinsizakalo zokwenziwa ngokwezifiso ukuze zilingane kangcono nezidingo zakho zocwaningo.
Imigomo Yokukhokha?I-invoyisi ye-Proforma izothunyelwa kuqala ngemva kokuqinisekiswa kwe-oda, kufakwe nemininingwane yethu yasebhange.Inkokhelo nge-T/T (Telex Transfer), PayPal, Western Union, njll.
Umsebenzi & Ukusetshenziswa kwe-N-Acetyl-L-Tyrosine (Ac-Tyr-OH; NALT) (CAS: 537-55-3) powder
1. I-N-Acetyl-L-Tyrosine iwumphumela we-acetyl we-amino acid, i-L-tyrosine.Incibilika ngokukhululekile emanzini uma iqhathaniswa ne-L-tyrosine futhi ivame ukusetshenziswa njengesengezo sokudla okunomsoco kwabazali.I-N-Acetyl-L-Tyrosine , uhlobo oluzinzile noluncibilika kakhulu lwe-tyrosine, lufakwe kwamanye amafomu atholakalayo okwamanje okuthengisa ama-amino acid afana ne-TrophAmine ne-Aminosyn-II.
2. I-N-Acetyl-L-Tyrosine ihileleke ekukhiqizeni i-catecholamine.Ingasetshenziswa njengengxenye yemidiya yesiko lamaseli ku-biomanufacture yezohwebo zamaphrotheni ahlanganisayo zokwelapha kanye namasosha omzimba e-monoclonal.
3. I-N-Acetyl-L-Tyrosine iyi-amino acid ebalulekile, okuwuhlobo lomsoco obalulekile womzimba womuntu nesilwane, ukukhula nokuthuthukiswa kudlala indima ebalulekile, ingasetshenziswa kabanzi ekudleni, kwezemithi njll.
4. I-N-Acetyl-L-Tyrosine idlala ingxenye edingekayo ekuhlanganisweni kwe-dopamine namanye amahomoni emzimbeni wakho.Ingakhuphula amazinga we-neurotransmitters i-dopamine, i-norepinephrine ne-epinephrine.Kuyasiza ukusekela amazinga aphezulu okugxila nokusebenza kwengqondo.Kungandisa inkumbulo yokusebenza kanye nemizwa yenhlalakahle.
5. I-N-Acetyl-L-Tyrosine ishintshiwe kusukela ku-Tyrosine evamile ngoba iqukethe ukungezwa kwe-acetic acid.Lokhu empeleni kusiza ukukhulisa i-bioavailability ye-compound ukuze imunceke kangcono emgudwini wegazi.
6. I-N-Acetyl-L-Tyrosine iwuhlobo olutholakala kakhulu lwe-L-Tyrosine lokwelapha okwandulela imizwa ephansi i-N-Acetyl-L-Tyrosine ingasetshenziswa ngemithamo ephansi kune-L-Tyrosine.I-L-Tyrosine evamile ayizinzile futhi ayincibiliki emanzini, okungase kuphumele ekuncishisweni kwe-bioavailability.
7. I-N-Acetyl-L-Tyrosine ithuthukisa ukunyibilika nokuzinza ikwenze kube uhlobo olumuncwa ngokushesha kakhulu futhi olutholakala nge-bioavailable lwe-amino acid L-Tyrosine engajwayele ukuphumela ngaphandle komchamo.
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