I-Omeprazole Sulfide CAS 73590-85-9 Purity >99.0% (HPLC) Factory
I-Ruifu Chemical Supply Omeprazole Iphakathi Nokuhlanzeka Okuphezulu
I-Omeprazole CAS 73590-58-6
I-Omeprazole Hydroxy Compound CAS 86604-78-6
I-Omeprazole Chloride Compound CAS 86604-75-3
I-Omeprazole Sulfide CAS 73590-85-9
2-Mercapto-5-Methoxybenzimidazole CAS 37052-78-1
I-2-Cyano-3-Methylpyridine CAS 20970-75-6
2,3,5-Trimethylpyridine CAS 695-98-7
Igama Lekhemikhali | I-Omeprazole sulfide |
Omqondofana | Ufiprazole;I-Omeprazole Sulfur Ether;I-Esomeprazol EP Ukungcola C;I-Omeprazole EP Ukungcola C;5-Methoxy-2-[[(4-Methoxy-3,5-Dimethyl-2-Pyridyl)methyl]thio]benzimidazole;5-Methoxy-2-{[(4-Methoxy-3,5-Dimethyl-2-Pyridinyl)methyl]thio}-1H-Benzimidazole |
Inombolo ye-CAS | 73590-85-9 |
Inombolo yeCAT | I-RF-PI1914 |
Isimo Sesitoko | Esitokweni, Isikali Sokukhiqiza Sifinyelela Kumathani |
I-Molecular Formula | I-C17H19N3O2S |
Isisindo samangqamuzana | 329.42 |
I-Melting Point | 122.0 ukuze 126.0 ℃ |
Ukuncibilika | I-Soluble ku-Methanol |
Ukuminyana | 1.28±0.10 g/cm3 |
Ibhrendi | I-Ruifu Chemical |
Into | Imininingwane |
Ukubukeka | Impushana emhlophe ukuya kokumhlophe noma amakristalu |
Ukuhlanzeka / Indlela Yokuhlaziya | >99.0% (HPLC) |
Ukulahlekelwa Ekumisweni | <1.00% |
Izinsalela ekushiseni | <0.20% |
Izinsimbi Ezisindayo (njenge-Pb) | <20ppm |
Ukungcola Okukodwa | <0.50% |
Ukungcola Okuphelele | <1.00% |
I-Infrared Spectrum | Ivumelana Nesakhiwo |
I-Proton NMR Spectrum | Ivumelana Nesakhiwo |
Izinga Lokuhlola | I-Enterprise Standard |
Ukusetshenziswa | Okumaphakathi kwe-Omeprazole / Esomeprazole |
Iphakheji: Ibhodlela, isikhwama se-Aluminium foil, 25kg/Cardboard Drum, noma ngokwemfuneko yekhasimende
Isimo Sesitoreji:Gcina ezitsheni ezivaliwe endaweni epholile neyomile;Vikela ekukhanyeni nakumswakama
I-Omeprazole Sulfide (CAS: 73590-85-9) iyisiphakathi esisetshenziswa ekukhiqizeni i-gastric proton pump inhibitors, i-Omeprazole (CAS: 73590-58-6) ne-Esomeprazole (CAS: 119141-88-7), i-Esomeprazole Sodium ( I-CAS: 161796-78-7).Njengomkhiqizo wokuwohloka, kubikwa ukuthi iyi-inhibitor esebenza ngokuqondile ye-cytochrome P450 2C19 kuma-microsomes esibindi somuntu esihlanganisiwe (IC50 = 9.7 μM).I-Omeprazole sulfide iyi-metabolite ye-Omeprazole.I-Esomeprazole Sodium uhlobo lukasawoti we-sodium lwe-esomeprazole.Kuyisidakamizwa esilwa nesilonda esisetshenziswa kakhulu, esasungulwa ngempumelelo yinkampani yaseSweden i-Astra Zeneca kuqala.Kungokwe-proton pump inhibitor.I-proton pump inhibitor iyisinqumo esiyinhloko sokwelapha isilonda se-peptic, isifo se-reflux ye-gastro-esophageal kanye nezinye izifo ezihlobene ne-asidi.Njengamanje i-PPI evame ukusetshenziswa emtholampilo ihlanganisa izinhlobo ezinhlanu: i-Omeprazole, i-Lansoprazole, i-Rabeprazole, i-Pantoprazole ne-Esomeprazole.Njenge-PPI yokuqala, ukusebenza ngempumelelo komuthi we-omeprazole ekwelapheni izifo ezihlobene ne-asidi kuye kwaqashelwa kabanzi.I-Esomeprazole iyi-S-isomer ye-Omeprazole, enganciphisa ukukhishwa kwe-asidi yesisu ngendlela ethile yokukhomba.Yisivimbeli esiqondile se-proton pump inhibitor kuseli ye-parietal.Ngenxa yenzuzo ye-metabolic ye-esomeprazole, inokutholakala okuphezulu kwe-bioavailability kanye ne-pharmacokinetics engaguquki kunozakwabo, i-Omeprazole Sodium, okwandisa umuthi ofinyelela empompini ye-proton.Indima yayo yokulawula i-asidi yesisu ingcono kakhulu kunamanye ama-proton pump inhibitors njengeLansoprazole, iPantoprazole, neRabeprazole.