I-Palbociclib CAS 571190-30-2 Ukuhlanzeka >99.5% (HPLC) Isithombe Esifakiwe Sefekthri ye-API

I-Palbociclib CAS 571190-30-2 Purity >99.5% (HPLC) API Factory

Incazelo emfushane:

Igama Lekhemikhali: Palbociclib

I-CAS: 571190-30-2

Ubumsulwa: >99.5% (HPLC)

Ukubukeka: Impushana Emhlophe noma Engamhlophe

I-API Ekwelapheni Umdlavuza Webele

Ikhwalithi Ephezulu, Ukukhiqizwa Kwezohwebo

E-Mail: alvin@ruifuchem.com

Thumela i-imeyili kithi

Imininingwane Yomkhiqizo

Imikhiqizo Ehlobene

Omaka bomkhiqizo

Incazelo:

I-Ruifu Chemical Supply Palbociclib Related Intermediate:
I-Palbociclib CAS 571190-30-2
5-Bromo-2,4-Dichloropyrimidine CAS 36082-50-5
5-Bromo-2-Chloro-N-Cyclopentylpyrimidin-4-Amine CAS 733039-20-8
tert-Butyl 4-(6-Nitropyridin-3-yl)piperazine-1-Carboxylate CAS 571189-16-7
tert-Butyl 4-(6-Amino-3-Pyridyl)piperazine-1-Carboxylate CAS 571188-59-5
6-Bromo-2-Chloro-8-Cyclopentyl-5-Methylpyrido-[2,3-d]pyrimidin-7(8H)-one CAS 1016636-76-2
2-Chloro-8-Cyclopentyl-5-Methyl-8H-Pyrido[2,3-d]pyrimidin-7-one CAS 1013916-37-4

Chemical Properties:

Igama Lekhemikhali	I-Palbociclib
Omqondofana	PD-0332991;Otava-Bb 1115529;Ibrance
Inombolo ye-CAS	571190-30-2
Isimo Sesitoko	Esitokweni, Isikali Sokukhiqiza Sifinyelela Kumathani
I-Molecular Formula	I-C24H29N7O2
Isisindo samangqamuzana	447.54
Ibhrendi	I-Ruifu Chemical

Imininingwane:

Into	Imininingwane
Ukubukeka	Impushana Emhlophe noma Engamhlophe
1H NMR Spectrum	Ihambisana Nesakhiwo
I-HPLC	Ihambisana Nesakhiwo
Izinto Ezihlobene
Ukungcola Ngamunye	<0.50%
Ukungcola Okuphelele	<1.00%
Ukulahlekelwa Ekumisweni	<0.50%
Izinsalela ekushiseni	<0.10%
Izinsimbi Ezisindayo	<10ppm
Ukuhlanzeka / Indlela Yokuhlaziya	>99.5% (HPLC)
Izinga Lokuhlola	I-Enterprise Standard
Ukusetshenziswa	I-API, Ekwelapheni Umdlavuza Webele

Iphakheji nesitoreji:

Iphakheji: Ibhodlela, isikhwama se-Aluminium foil, 25kg/Cardboard Drum, noma ngokwemfuneko yekhasimende

Isimo Sesitoreji:Gcina ezitsheni ezivaliwe endaweni epholile neyomile;Vikela ekukhanyeni nakumswakama

Izinzuzo:

I-FAQ:

Isicelo:

I-Palbociclib (i-CAS: 571190-30-2) iyi-inhibitor etholakala ngomlomo ye-cyclin-dependent kinase (CDK) enomsebenzi ongaba khona we-antineoplastic.I-Palbociclib ivimbela ngokukhethayo i-cyclin-dependent kinase 4 (CDK4) kanye ne-6 (CDK6), ngaleyo ndlela ivimbele i-retinoblastoma (Rb) iphrotheni phosphorylation ekuqaleni kwesigaba se-G1 okuholela ekuboshweni komjikelezo weseli.Lokhu kucindezela ukuphindaphinda kwe-DNA futhi kunciphisa ukwanda kwamaseli e-tumor.I-Palbociclib ingummeleli wokuqala wesigaba esisha somuthi we-cyclin-dependent kinase inhibitors.Lo mphumela ukhawulela ukwanda kwamaseli (ukukhula kwamaseli nokuhlukana).Isetshenziswa njenge-antineoplastic ejenti kumdlavuza webele othuthukile noma we-metastatic.