I-Palbociclib Intermediate CAS 1013916-37-4 Ubumsulwa >99.0% (HPLC) Isithombe Esifakiwe Sefekthri Sekhwalithi Ephakeme

I-Palbociclib Intermediate CAS 1013916-37-4 Ubumsulwa >99.0% (HPLC) Factory High Quality

Incazelo emfushane:

Igama Lekhemikhali: 2-Chloro-8-Cyclopentyl-5-Methyl-8H-Pyrido[2,3-d]pyrimidin-7-one

I-CAS: 1013916-37-4

Ubumsulwa: >99.0% (HPLC)

Ukubukeka: Impushana Ephuzi Epholile

I-Intermediate of of Palbociclib (CAS: 571190-30-2)

Ikhwalithi Ephezulu, Ukukhiqizwa Kwezohwebo

E-Mail: alvin@ruifuchem.com

Thumela i-imeyili kithi

Imininingwane Yomkhiqizo

Imikhiqizo Ehlobene

Omaka bomkhiqizo

Incazelo:

I-Ruifu Chemical Supply Palbociclib Related Intermediate:
I-Palbociclib CAS 571190-30-2
5-Bromo-2,4-Dichloropyrimidine CAS 36082-50-5
5-Bromo-2-Chloro-N-Cyclopentylpyrimidin-4-Amine CAS 733039-20-8
tert-Butyl 4-(6-Nitropyridin-3-yl)piperazine-1-Carboxylate CAS 571189-16-7
tert-Butyl 4-(6-Amino-3-Pyridyl)piperazine-1-Carboxylate CAS 571188-59-5
6-Bromo-2-Chloro-8-Cyclopentyl-5-Methylpyrido-[2,3-d]pyrimidin-7(8H)-one CAS 1016636-76-2
2-Chloro-8-Cyclopentyl-5-Methyl-8H-Pyrido[2,3-d]pyrimidin-7-one CAS 1013916-37-4

Chemical Properties:

Igama Lekhemikhali	2-Chloro-8-Cyclopentyl-5-Methyl-8H-Pyrido[2,3-d]pyrimidin-7-one
Omqondofana	2-Chloro-8-Cyclopentyl-5-Methylpyrido[2,3-d]pyrimidin-7(8H)-one;I-Palbociclib Intermediate 2
Inombolo ye-CAS	1013916-37-4
Inombolo yeCAT	I-RF-PI1847
Isimo Sesitoko	Esitokweni, Isikali Sokukhiqiza Sifinyelela Kumathani
I-Molecular Formula	I-C13H14ClN3O
Isisindo samangqamuzana	263.72
Ukuncibilika kwamanzi	Incibilika Kancane Emanzini
Ibhrendi	I-Ruifu Chemical

Imininingwane:

Into	Imininingwane
Ukubukeka	Impushana Ephuzi Equlekile
Ukuhlanzeka / Indlela Yokuhlaziya	>99.0% (HPLC)
Umswakama (KF)	<0.50%
Izinsalela ekushiseni	<0.20%
Ukungcola Okuphelele	<1.00%
Izinga Lokuhlola	I-Enterprise Standard
Ukusetshenziswa	I-Intermediate of Palbociclib (CAS: 571190-30-2)

Iphakheji nesitoreji:

Iphakheji: Ibhodlela, isikhwama se-Aluminium foil, 25kg/Cardboard Drum, noma ngokwemfuneko yekhasimende

Isimo Sesitoreji:Gcina ezitsheni ezivaliwe endaweni epholile neyomile;Vikela ekukhanyeni nakumswakama

Izinzuzo:

I-FAQ:

Isicelo:

I-2-Chloro-8-cyclopentyl-5-methyl-8H-pyrido[2,3-d]pyrimidin-7-one (CAS: 1013916-37-4) isetshenziswa njengendawo ephakathi yemithi ye-Palbociclib (CAS: 571190-30 -2).I-Palbociclib umuthi wokwelapha umdlavuza webele we-ER-positive kanye ne-HER2-negative owenziwe.Kuyi-inhibitor ekhethiwe ye-cyclin-dependent kinases CDK4 kanye ne-CDK6.Palbociclib kwakuyi-CDK4/6 inhibitor yokuqala ukugunyazwa njengokwelashwa komdlavuza kunoma iyiphi inhlangano, futhi kusukela ngo-December 2017 inqunywe izikhathi ezingaphezu kwezingu-90,000.