I-Paroxetine Hydrochloride Hemihydrate CAS 110429-35-1 Assay 97.5~102.0% Factory

Incazelo emfushane:

Igama: I-Paroxetine Hydrochloride Hemihydrate

I-CAS: 110429-35-1

I-Assay (Into Engenamanzi): 97.5~102.0%

Ukubukeka: I-Crystalline Powder Emhlophe noma Cishe Emhlophe

Ikhwalithi ephezulu ye-API, Ukukhiqiza Kwezentengiso

E-Mail: alvin@ruifuchem.com


Imininingwane Yomkhiqizo

Imikhiqizo Ehlobene

Omaka bomkhiqizo

Incazelo:

Chemical Properties:

Igama Lekhemikhali I-Paroxetine Hydrochloride Hemihydrate
Omqondofana (3S,4R)-(-)-3-[(1,3-Benzodioxol-5-yloxy)methyl]-4-(4-fluorophenyl)piperidine Hydrochloride Hemihydrate;Paxil;I-Seroxat;I-BRL29060 Hydrochloride Hemihydrate;I-BRL29060A Hemihydrate;I-Paroxetine-D4 HCl
Inombolo ye-CAS 110429-35-1
Inombolo yeCAT I-RF-PI1946
Isimo Sesitoko Esitokweni, Isikali Sokukhiqiza Sifinyelela Kumathani
I-Molecular Formula C19H20FNO3·HCl·1/2H2O
Isisindo samangqamuzana 374.84
I-Melting Point 140.0 ~ 143.0℃
Ukuzungezisa Okuthile [α]20/D -88.0° ukuya -92.0° (C=1, MeOH, Calcd.on anh.substance)
Ukuncibilika Ayincibiliki Emanzini;I-Soluble kakhulu ku-Dimethylformamide, i-Methanol;Incibilika ku-Ethanol
Ibhrendi I-Ruifu Chemical

Imininingwane:

Okuqukethwe Imininingwane Imiphumela
Ukubukeka
I-Crystalline Powder Emhlophe noma Cishe Emhlophe Vumelanisa
Ukuhlonza A
I-spectrum yokumuncwa kwe-infrared kufanele ihambisane ne-spectrum yereferensi Vumelanisa
Ukuhlonza B Indawo ephakeme kakhulu kanye nesikhathi sokugcina sesixazululo sokuhlola kufanele sihambisane nesixazululo sereferensi Vumelanisa
Ukuhlonza C Amanzi (nge-KF) Vumelanisa
Identification D Ukusabela kwe-Chlorides Vumelanisa
Ukungcola D
≤0.20% Akekho
Ukungcola G ≤0.001%  
Izinto Ezihlobene
Ukungcola A: ≤0.30% 0.03%
Ukungcola Okungacacisiwe: Ngokungcola ngakunye, ≤0.10% 0.06%
Ukungcola okuphelele: ≤0.50% 0.10%
Izinsimbi Ezisindayo ≤0.002% <0.002%
Amanzi (nge-KF) 2.20%~2.70% 2.46%
I-Sulfated Ash ≤0.10% <0.10%
Isivivinyo 97.5%~102.0% (Into Engenamanzi) 100.2%
Izincibilikisi Ezisele
I-Methanol ≤0.30% 0.001%
I-acetone ≤0.50% 0.001%
Isopropanol ≤0.50% 0.04%
I-Dichloromethane ≤0.06% Lutho
I-Toluene ≤0.089% 0.003%
Isiphetho: Ukuhambisana ne-EP7.0.

Iphakheji nesitoreji:

Iphakheji: Ibhodlela, isikhwama se-Aluminium foil, 25kg/Cardboard Drum, noma ngokwemfuneko yekhasimende

Isimo Sesitoreji:Gcina ezitsheni ezivaliwe endaweni epholile neyomile;Vikela ekukhanyeni nakumswakama

Izinzuzo:

1

I-FAQ:

Isicelo:

I-Paroxetine Hydrochloride Hemihydrate (i-CAS: 110429-35-1) ingenye yezinto ezinamandla kakhulu futhi ezikhethiwe ze-serotonin reuptake inhibitors (SSRI);i-antidepressant.Iphuma ku-phenylpiperidine, inamandla kakhulu futhi ikhetha i-ST (i-serotonin transporter/5-HT) inhibitor yokuthatha.Isebenza ngokubophezela ku-ST (i-serotonin transporter/SERT) enobungane obuphezulu (Ki = 05 nM).I-Antidepressant kanye ne-anxiolytic in vivo.I-Paroxetine hydrochloride ingasetshenziswa ukwelapha ukudangala, okuwumuthi omusha oqeda ukucindezeleka.Ingase futhi isetshenziselwe ukwelapha i-panic attack, i-generalized anxiety disorder, social disorder disorder, obsessive-compulsive disorder (OCD), ukuqwasha, i-premenstrual syndrome, ukuphuma isidoda ngaphambi kwesikhathi kanye nezinye izifo, ngomphumela omuhle wokwelapha kanye nokusabela okuncane okubi.Yelapha zonke izinhlobo zokucindezeleka.Kubandakanya ukudangala nokukhathazeka nokudangala okusebenzayo.Izimpawu ezivamile zokucindezeleka: ukukhathala, ukuphazamiseka kokulala, ukungabi nesithakazelo nokuzijabulisa emisebenzini yansuku zonke, ukulahlekelwa ukudla.Ngemuva kokuthi umphumela wokwelapha usunelisekile, ungavimbela ukuphindaphinda kokucindezeleka.

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