I-Paroxetine Hydrochloride Hemihydrate CAS 110429-35-1 Assay 97.5~102.0% Factory
I-Ruifu Chemical Supply With High Purity
I-Paroxetine Hydrochloride Hemihydrate CAS 110429-35-1
I-N-Methyl Paroxetine CAS 110429-36-2
Igama Lekhemikhali | I-Paroxetine Hydrochloride Hemihydrate |
Omqondofana | (3S,4R)-(-)-3-[(1,3-Benzodioxol-5-yloxy)methyl]-4-(4-fluorophenyl)piperidine Hydrochloride Hemihydrate;Paxil;I-Seroxat;I-BRL29060 Hydrochloride Hemihydrate;I-BRL29060A Hemihydrate;I-Paroxetine-D4 HCl |
Inombolo ye-CAS | 110429-35-1 |
Inombolo yeCAT | I-RF-PI1946 |
Isimo Sesitoko | Esitokweni, Isikali Sokukhiqiza Sifinyelela Kumathani |
I-Molecular Formula | C19H20FNO3·HCl·1/2H2O |
Isisindo samangqamuzana | 374.84 |
I-Melting Point | 140.0 ~ 143.0℃ |
Ukuzungezisa Okuthile [α]20/D | -88.0° ukuya -92.0° (C=1, MeOH, Calcd.on anh.substance) |
Ukuncibilika | Ayincibiliki Emanzini;I-Soluble kakhulu ku-Dimethylformamide, i-Methanol;Incibilika ku-Ethanol |
Ibhrendi | I-Ruifu Chemical |
Okuqukethwe | Imininingwane | Imiphumela |
Ukubukeka | I-Crystalline Powder Emhlophe noma Cishe Emhlophe | Vumelanisa |
Ukuhlonza A | I-spectrum yokumuncwa kwe-infrared kufanele ihambisane ne-spectrum yereferensi | Vumelanisa |
Ukuhlonza B | Indawo ephakeme kakhulu kanye nesikhathi sokugcina sesixazululo sokuhlola kufanele sihambisane nesixazululo sereferensi | Vumelanisa |
Ukuhlonza C | Amanzi (nge-KF) | Vumelanisa |
Identification D | Ukusabela kwe-Chlorides | Vumelanisa |
Ukungcola D | ≤0.20% | Akekho |
Ukungcola G | ≤0.001% | |
Izinto Ezihlobene | Ukungcola A: ≤0.30% | 0.03% |
Ukungcola Okungacacisiwe: Ngokungcola ngakunye, ≤0.10% | 0.06% | |
Ukungcola okuphelele: ≤0.50% | 0.10% | |
Izinsimbi Ezisindayo | ≤0.002% | <0.002% |
Amanzi (nge-KF) | 2.20%~2.70% | 2.46% |
I-Sulfated Ash | ≤0.10% | <0.10% |
Isivivinyo | 97.5%~102.0% (Into Engenamanzi) | 100.2% |
Izincibilikisi Ezisele | ||
I-Methanol | ≤0.30% | 0.001% |
I-acetone | ≤0.50% | 0.001% |
Isopropanol | ≤0.50% | 0.04% |
I-Dichloromethane | ≤0.06% | Lutho |
I-Toluene | ≤0.089% | 0.003% |
Isiphetho: Ukuhambisana ne-EP7.0. |
Iphakheji: Ibhodlela, isikhwama se-Aluminium foil, 25kg/Cardboard Drum, noma ngokwemfuneko yekhasimende
Isimo Sesitoreji:Gcina ezitsheni ezivaliwe endaweni epholile neyomile;Vikela ekukhanyeni nakumswakama
I-Paroxetine Hydrochloride Hemihydrate (i-CAS: 110429-35-1) ingenye yezinto ezinamandla kakhulu futhi ezikhethiwe ze-serotonin reuptake inhibitors (SSRI);i-antidepressant.Iphuma ku-phenylpiperidine, inamandla kakhulu futhi ikhetha i-ST (i-serotonin transporter/5-HT) inhibitor yokuthatha.Isebenza ngokubophezela ku-ST (i-serotonin transporter/SERT) enobungane obuphezulu (Ki = 05 nM).I-Antidepressant kanye ne-anxiolytic in vivo.I-Paroxetine hydrochloride ingasetshenziswa ukwelapha ukudangala, okuwumuthi omusha oqeda ukucindezeleka.Ingase futhi isetshenziselwe ukwelapha i-panic attack, i-generalized anxiety disorder, social disorder disorder, obsessive-compulsive disorder (OCD), ukuqwasha, i-premenstrual syndrome, ukuphuma isidoda ngaphambi kwesikhathi kanye nezinye izifo, ngomphumela omuhle wokwelapha kanye nokusabela okuncane okubi.Yelapha zonke izinhlobo zokucindezeleka.Kubandakanya ukudangala nokukhathazeka nokudangala okusebenzayo.Izimpawu ezivamile zokucindezeleka: ukukhathala, ukuphazamiseka kokulala, ukungabi nesithakazelo nokuzijabulisa emisebenzini yansuku zonke, ukulahlekelwa ukudla.Ngemuva kokuthi umphumela wokwelapha usunelisekile, ungavimbela ukuphindaphinda kokucindezeleka.